Live data from Hacker News

Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

mdedge.com

41–50 of 122 posts

Re: Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

#41

Earlier quoted context omitted.

Please refrain from simply quoting the article, adding nothing to the conversation. It’s a blatant attempt at upvote harvesting from the TLDR crowd, and doesn’t belong on HN

The article is behind a paywall and I thought this snippet properly summarized it.

Hi Miguel. It wasn’t behind a paywall for me. Thanks for clarifying - and I apologise for being snarky.

Re: Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

#43

Earlier quoted context omitted.

If you are out there and suffer daily 'stage fright' or serious social anxiety - propranolol is the drug for you. That weird fear that sweeps over you before a conversation - just doesn't happen. Need to talk in front of 50 people in 25 minutes? No problem. If you are crippled by social anxiety - this pill will turn you into Bradley Cooper in Limitless.

Maybe I’m an outlier, but it had absolutely no effect on me for public speaking or social situations. I was prescribed a lot of it, tried for years and even still have some sitting around. I envy those who get the effects you describe.

It didn't help me either. Never trust anyone saying something is a miracle drug. They are storytellers, not scientists.

Re: Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

#45
I bet this discovery is related to another recent discovery: "Blocking IgSF9b in pathologically anxious mice has an anxiolytic effect and normalises anxiety behaviour in these animals." (see https://www.mpg.de/12620765/anxiety-protein-amygdala)

Re: Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

#48
I'm really curious where social anxiety comes from. I get it though not crippling most of the time. But for example public speaking I can logically see that I publicly speak any time I'm at dinner with friends or voice my thoughts in a meeting so it's strange to me that officially speaking would have so different a feeling but it does.

Re: Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

#49

Is there some way to see this without the paywall? I realize I’m just one data point, but as someone with anxiety, I studied up on the use of propranolol in fear extinction and was able to get my doctor to prescribe it around 5 years ago. It had absolutely no positive effect on me. I may as well have been taking aspirin. It did, however seem to have some negative effects on my memory. If I met someone while on it, I…

https://outline.com/VRzuMJ

Re: Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

#50

Earlier quoted context omitted.

The article is behind a paywall and I thought this snippet properly summarized it.

> The article is behind a paywall I didn't see one.

I had access at first. On reload it redirected to a paywall.

https://outline.com/VRzuMJ

Post reply on HN