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Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

mdedge.com

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Re: Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

#2
> The researchers next conducted a randomized, double-blind clinical trial in 45 individuals with arachnophobia. Fifteen received 40 mg of propranolol after spending 2 minutes in proximity to a large tarantula, 15 got placebo, and another 15 received propranolol without exposure to a tarantula. One week later, all patients who received propranolol with spider exposure were able to approach and actually pet the tarantula.

Re: Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

#4

Incredible, amazing, wonderful -- and a bit scary. Imagine this being used to erase more complex memories, like that person you dated for two weeks that broke your heart.

The way I understood the article is that the knowledge is not removed. Just the learned anxiety related to the knowledge.

Re: Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

#5

Incredible, amazing, wonderful -- and a bit scary. Imagine this being used to erase more complex memories, like that person you dated for two weeks that broke your heart.

No knowledge is lost, just the emotional reaction.

Re: Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

#6

Incredible, amazing, wonderful -- and a bit scary. Imagine this being used to erase more complex memories, like that person you dated for two weeks that broke your heart.

I really wish people would RTFA before commenting.

Re: Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

#7

> The researchers next conducted a randomized, double-blind clinical trial in 45 individuals with arachnophobia. Fifteen received 40 mg of propranolol after spending 2 minutes in proximity to a large tarantula, 15 got placebo, and another 15 received propranolol without exposure to a tarantula. One week later, all patients who received propranolol with spider exposure were able to approach and actually pet the tarant…

Please refrain from simply quoting the article, adding nothing to the conversation. It’s a blatant attempt at upvote harvesting from the TLDR crowd, and doesn’t belong on HN

Re: Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

#10
> The propranolol must be given within roughly an hour before to 1 hour after therapeutic reactivation of the fear memory to be effective. [...] when subjects were rechallenged 12 hours after taking propranolol the previous day – that is, after a night’s sleep – the fear memory was gone

Oh wow, I'd be keen to give it a go:

1. Standing next to an edge of a tall building.

2. In a tightly enclosed space.

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