I sometimes use a local resolver bound to localhost that blocks ads by pointing to a custom root.
If someone aiming to be on the TRR list sets up a remote resolver that blocks ads (or replaces them with blank images) perhaps using the same technique, it could allow Firefox users to get ad blocking by default, by using DOH.
I wonder if that would violate Mozilla's requirements?
Are ads considered "content"?
There is of course precedent for blocking undesirable content via DNS as a "service".
Third party DNS service, for example the famous one that starts with "O", has been used to block certain content, e,g, at schools.
This was offered as a fee-based service.
If I remember correctly they also offered "free" service which was subject to redirection of NXDOMAIN to paid placement "search" results/ads.