How Sitting For Long Periods Affects Your Metabolism
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How Sitting For Long Periods Affects Your Metabolism
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Re: How Sitting For Long Periods Affects Your Metabolism
#2I wonder if intensity matters. What would the response be if instead of treadmill one lifted weights with high intensity.
Re: How Sitting For Long Periods Affects Your Metabolism
#3This report triggered several of my alarm bells, so I investigated further. I had a look at the quoted study.
"RESULTS: No differences between trials ( P > 0.05) were found in the overall plasma triglyceride, glucose, or insulin responses during the HFGTT. "
It takes some balls to dismiss a study based on one sentence in the abstract, but this is an admission of a common and fatal mistake, so I'm going to do exactly that.
They're claiming there is no difference between groups because they were unable to show that, if there was an inherent difference, the chance they'd see these results is at most 5%. There's an easy way to obtain such a result: small sample size. And, indeed, they only compared 2 groups of 5 people.
There is a proper way to show two groups are the same, and it's called "equivalence testing." It has the same kind of statistical requirements that normal testing does. What they did instead is totally statically invalid.
There's not a soft way to put it: this study proves nothing. Let it be an example in training your defenses against bad science.
Re: How Sitting For Long Periods Affects Your Metabolism
#4This report triggered several of my alarm bells, so I investigated further. I had a look at the quoted study. "RESULTS: No differences between trials ( P > 0.05) were found in the overall plasma triglyceride, glucose, or insulin responses during the HFGTT. " It takes some balls to dismiss a study based on one sentence in the abstract, but this is an admission of a common and fatal mistake, so I'm going to do exactly…
The results themselves are not wrong per se. Reaching this conclusion from those results, however, is frankly insulting and should make all authors of the paper ashamed.
> These data indicate that physical inactivity (e.g., sitting ~13.5 hrs/day and Also note that the researchers _immediately_ re-fed the group who participated in the intense exercise:
> The additional energy expenditure from the exercise session was estimated via indirect calorimetry. This energy was then replaced with additional caloric intake with the post-exercise dinner (Clif® Builder’s®; ~40%/30%/30% of calories from carbohydrate, fat, and protein, respectively).
This is especially bad because it isn't mentioned anywhere in the abstract (I checked the full-text).
Shit science.
Re: How Sitting For Long Periods Affects Your Metabolism
#5This report triggered several of my alarm bells, so I investigated further. I had a look at the quoted study. "RESULTS: No differences between trials ( P > 0.05) were found in the overall plasma triglyceride, glucose, or insulin responses during the HFGTT. " It takes some balls to dismiss a study based on one sentence in the abstract, but this is an admission of a common and fatal mistake, so I'm going to do exactly…
I also wanted to dig into this. The null hypothesis and burden-of-proofs change between p tests and equivalence testing, right?
P tests: null hypothesis is that there is nothing different, burden of proof to suggest there is a difference.
Equivalence testing: null hypothesis is that there is something different, burden of proof to suggest there is no difference.
But maybe this is just a misapplied p-test? So while the "RESULTS" section of the paper is fine:
No differences between trials ( P > 0.05) were found in the overall plasma triglyceride, glucose, or insulin responses during the HFGTT.
The "CONCLUSION" section is where they invert the statistics of their own study and literally suggest a p-test-able difference despite their results section literally concluding a p-test-able non-difference:
These data indicate that physical inactivity (e.g., sitting ~13.5 hrs/day and
Re: How Sitting For Long Periods Affects Your Metabolism
#6This report triggered several of my alarm bells, so I investigated further. I had a look at the quoted study. "RESULTS: No differences between trials ( P > 0.05) were found in the overall plasma triglyceride, glucose, or insulin responses during the HFGTT. " It takes some balls to dismiss a study based on one sentence in the abstract, but this is an admission of a common and fatal mistake, so I'm going to do exactly…
Excellent analysis!
For those interested, here's the study the article quotes: https://www.ncbi.nlm.nih.gov/pubmed/30763169
Re: How Sitting For Long Periods Affects Your Metabolism
#7This report triggered several of my alarm bells, so I investigated further. I had a look at the quoted study. "RESULTS: No differences between trials ( P > 0.05) were found in the overall plasma triglyceride, glucose, or insulin responses during the HFGTT. " It takes some balls to dismiss a study based on one sentence in the abstract, but this is an admission of a common and fatal mistake, so I'm going to do exactly…
Can you explain this common mistake further?
> They're claiming there is no difference between groups because they were unable to show that, if there was an inherent difference, the chance they'd see these results is at most 5%.
It seems to me that they're claiming that they failed to reject the null hypothesis, the end. I.e. according to this statistic, there was no significant difference in the means between all groups in the ANOVA. This was a small sample size, but the analysis seems to include multiple trials for each participant.
This seems like a standard use of ANOVA to me. So how can you say that the alpha value is wrong just based on this one sentence from the abstract? It seems to me that you'd have to know the domain, know what effect to expect, and so on
Re: How Sitting For Long Periods Affects Your Metabolism
#8I wonder if intensity matters. What would the response be if instead of treadmill one lifted weights with high intensity.
It depends on the fitness level of the subjects. The more fit they are, the less low intensity exercise (treadmill) is effective.
More info here: https://roguehealthandfitness.com/importance-exercise-intens...
Re: How Sitting For Long Periods Affects Your Metabolism
#9This report triggered several of my alarm bells, so I investigated further. I had a look at the quoted study. "RESULTS: No differences between trials ( P > 0.05) were found in the overall plasma triglyceride, glucose, or insulin responses during the HFGTT. " It takes some balls to dismiss a study based on one sentence in the abstract, but this is an admission of a common and fatal mistake, so I'm going to do exactly…
Can you explain this common mistake further? > They're claiming there is no difference between groups because they were unable to show that, if there was an inherent difference, the chance they'd see these results is at most 5%. It seems to me that they're claiming that they failed to reject the null hypothesis, the end. I.e. according to this statistic, there was no significant difference in the means between all gr…
Not OP, but [0]:
> If the data do not contradict the null hypothesis, then only a weak conclusion can be made: namely, that the observed data set provides no strong evidence against the null hypothesis. In this case, because the null hypothesis could be true or false, in some contexts this is interpreted as meaning that the data give insufficient evidence to make any conclusion; in other contexts it is interpreted as meaning that there is no evidence to support changing from a currently useful regime to a different one.
Also, keep in mind that in this study, the intervention (the difference between both groups) was, basically: perform an intense 1-hour bout of exercise and immediately replenish all calories spent.
The null hypothesis is, thus:
"In sedentary people, performing an intense bout of exercise and immediately replenishing spent calories doesn't affect next day metabolism."
Being unable to reject that statement doesn't immediately confirm it in statistical terms, but even if that were the case, it is such a lousy statement to begin with, that any headlines coming out of it are outright misinformation. Both groups were equally sedentary and that might have nothing to do with any observed effects.
Re: How Sitting For Long Periods Affects Your Metabolism
#10This report triggered several of my alarm bells, so I investigated further. I had a look at the quoted study. "RESULTS: No differences between trials ( P > 0.05) were found in the overall plasma triglyceride, glucose, or insulin responses during the HFGTT. " It takes some balls to dismiss a study based on one sentence in the abstract, but this is an admission of a common and fatal mistake, so I'm going to do exactly…
Makes you wonder what they're selling.
Get a few sites to pick up a bogus scientific study article supporting a new product they're releasing is a thing.