61–70 of 106 posts
Doing my best to summarize the effects of 5-HTP and its' corresponding pubmed research: https://nutripeek.com/detail/5-htp
Do you know anything about how EGCG affects absorption of 5-HTP? I've read in several places that 5-HTP is more effective when consumed with EGCG (green tea extract), but I'm not sure if this is just urban legend or if it has any real–world effects.
People in this thread are repeating the myth that exercise is a treatment for depression, when all the evidence we have shows that it probably isn't. The article links to an old version of the NICE guidance. The new version of that is here: https://www.nice.org.uk/guidance/cg90 It's important to note that exercise isn't being touted as a treatment for depression, but as something that may help people with sub-clinica…
People commonly use the term "depression" in a way that does not exactly match the true medical definition. People say "i'm depressed" when they should really say "i'm feeling sad today". People say exercise is a treatment, when they should say it makes them feel better. I fear your pursuit for the exact terms might prevent some people from trying a thing that would help them.
[1] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989833/
[2] - https://www.health.harvard.edu/depression/is-your-antidepres...
So many people (including doctors) seem to be set on the idea that serotonin makes you happy and therefore is the solution to depression. This is only half true, and not in the way that most think. Serotonin (if high) makes you numb [1]. But that might be the lesser of two evils when it comes to depression [2], which is why it’s become popular as a mechanism to treat it. It not a solution, it’s just masking the under…
So many people (including doctors) seem to be set on the idea that serotonin makes you happy and therefore is the solution to depression. This is only half true, and not in the way that most think. Serotonin (if high) makes you numb [1]. But that might be the lesser of two evils when it comes to depression [2], which is why it’s become popular as a mechanism to treat it. It not a solution, it’s just masking the under…
So many people (including doctors) seem to be set on the idea that serotonin makes you happy and therefore is the solution to depression. This is only half true, and not in the way that most think. Serotonin (if high) makes you numb [1]. But that might be the lesser of two evils when it comes to depression [2], which is why it’s become popular as a mechanism to treat it. It not a solution, it’s just masking the under…
I do wonder though if it does make you numb if that isn't always bad. For some people depression might be related to an excess of sensitivity or some past trauma. Numbing that a bit might help them move past it and might be beneficial to their healing. Of course this might not be the case for people whose depression has some other source and it might not be the case for continuing treatment. It's possible that some people might benefit from taking certain drugs for a period of time but not forever.
It's all quite complex, individual, and not yet anywhere close to fully understood.
So many people (including doctors) seem to be set on the idea that serotonin makes you happy and therefore is the solution to depression. This is only half true, and not in the way that most think. Serotonin (if high) makes you numb [1]. But that might be the lesser of two evils when it comes to depression [2], which is why it’s become popular as a mechanism to treat it. It not a solution, it’s just masking the under…
That does beg the interesting question that if you don't feel depressed, are you really depressed?
Interesting review of non-drug approaches to depression and mood: - Alterations in thought (meditation) - Exposure to bright light (outdoors) - Exercise - tryptophan supplementation taken WITHOUT food for greater uptake - α-Lactalbumin found in Milk but not really a great option Definitely can speak to the exposure to light, and exercise ones. Nothing lifts my mood more than going for a run outside, in the heat of th…
Earlier quoted context omitted.
Didn't read the article but surprised 5-HTP not mentioned?
Tryptophan itself as a component of food is mentioned however, as well as tryptophan supplementation. I'd consider 5-htp and L-tryptophan to be under that "tryptophan supplementation" umbrella. The difference between 5htp and l-tryptophan is that the former doesn't require a transport molecule to get past the blood-brain barrier, so it [citation needed] converts to serotonin quicker, whereas with l-tryptophan there's…
I have a seasonal depression diagnosis and lifting weights has been by far the best treatment for me. Meditation, light therapy, and vitamins/nootropics are all good on their own, they each sort of take away some of the symptoms, but I wouldn't say the depression isn't still there. But weightlifting is incredible. I feel amazing after a heavy session - deadlifting and benching especially give me a kind of euphoria. G…
[1] - https://jamanetwork.com/journals/jamapsychiatry/article-abst...