Earlier quoted context omitted.
You're confusing sex and gender.
the people who change genders disagree
XX and XY doesn't change though.
New study provides evidence that we need different drugs for men and women
31–40 of 71 posts
Re: New study provides evidence that we need different drugs for men and women
#32The mechanism of action of analgesic drugs is very simple and well-understood. Considering the fact that the very same painkillers that humans use are effective on drastically different organisms, such as snails or crustaceans, I find it extremely unlikely that gender plays any significant role in their effectiveness. To be honest, it feels like this study was politically motivated.
> The mechanism of action of analgesic drugs is very simple and well-understood.
https://academic.oup.com/bjaed/article/14/4/153/293533 (2013)
the exact mechanism of action of paracetamol [ie acetamophen] remains to be determined. There is evidence for a number of central mechanisms, including effects on prostaglandin production, and on serotonergic, opioid, nitric oxide (NO), and cannabinoid pathways, and it is likely that a combination of interrelated pathways are in fact involved.
That's the most widely-used analgesic in the world, and its mechanism is evidently neither simple nor well-understood.
Re: New study provides evidence that we need different drugs for men and women
#33So slowly, it seems we are going back to the primitive healer's approach where they did not had a specific drug for a specific disease, but rather they made a individual combination of drugs (and other methods) for every individuals problems.
Because, of course men and women are different so it should not be surprising that they react differently to drugs, but also men or women in itself are very different, depending on their genes obviously, but also their age, their routines, their diet etc.
So good to hear, that we are going one more step away, from the generalistic approach. Which was a cheap way, thats why it did produced results as well, but maybe not the best results.
Re: New study provides evidence that we need different drugs for men and women
#34No! We're all the same and must get EXACTLY the same treatment, no matter gender or ethnicity.
Re: New study provides evidence that we need different drugs for men and women
#35The article starts out with saying that drug development begins with studies on male rats and mice, but then goes on to describe difference the biological pathways for pain in men and women. That creates some obvious question. How similar is the pain pathways between humans and rats, and is it more similar than between women and men?
There should basically be 6 sources of differences. Animal M vs Human M, Animal F vs human F, Animal M vs Human F, Animal F vs Human M, Animal F vs Animal M, and last Human M vs Human F.
A difference in any of those could potential cause a wrong conclusion in a study. The question I hope researcher has is which of those are more likely to have a significant difference in pain research
Re: New study provides evidence that we need different drugs for men and women
#36Good luck transgender
Re: New study provides evidence that we need different drugs for men and women
#37And women also display different cardiac symptoms from men https://outline.com/aYwSJV
Re: New study provides evidence that we need different drugs for men and women
#38I'd ask everyone who came to this article with the assumption that someone would object to or get offended by this finding, to actually observe if anyone does.
Right above you, someone getting offended that there aren’t enough trans people in the study. I thought that was an interesting coincidence. https://pasteboard.co/I6fhTWy.jpg
That account has a long history of obvious concern trolling.
Re: New study provides evidence that we need different drugs for men and women
#39So slowly, it seems we are going back to the primitive healer's approach where they did not had a specific drug for a specific disease, but rather they made a individual combination of drugs (and other methods) for every individuals problems. Because, of course men and women are different so it should not be surprising that they react differently to drugs, but also men or women in itself are very different, depending…
Yes. Ayurveda does treat every individual differently and does customized medicine on case-by-case basis after observing the patient carefully asking questions that provide root cause and then make a medicine that only works for that individual for that issue alone. No side effects. Modern medicine treats every one equal and prints a list of side effects on drugs as if they are nothing. But it is the body's way of saying it is not happy with whatever external chemical he has taken is not for that body! Finally it's a good step which modern medicine is ignoring for ages even after advised by a few before.
Re: New study provides evidence that we need different drugs for men and women
#40Link to another recent study related to pain differences between men and women (Male-Specific Conditioned Pain Hypersensitivity in Mice and Humans) https://www.cell.com/current-biology/fulltext/S0960-9822(18)...