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New study provides evidence that we need different drugs for men and women

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Re: New study provides evidence that we need different drugs for men and women

#21

Post by garmaine »

xeeeeeeeeeeenu wrote: post #15

The mechanism of action of analgesic drugs is very simple and well-understood. Considering the fact that the very same painkillers that humans use are effective on drastically different organisms, such as snails or crustaceans, I find it extremely unlikely that gender plays any significant role in their effectiveness. To be honest, it feels like this study was politically motivated.

Since ibuprofen impairs testosterone production, a key sex differentiating hormone, I'd not be surprised at all if there is a gender correlation in effectiveness or side effects.

Re: New study provides evidence that we need different drugs for men and women

#22

Post by tomlock »

Swizec wrote: post #18
tomlock wrote: post #12

I'd ask everyone who came to this article with the assumption that someone would object to or get offended by this finding, to actually observe if anyone does.

Right above you, someone getting offended that there aren’t enough trans people in the study. I thought that was an interesting coincidence. https://pasteboard.co/I6fhTWy.jpg

Seems like a reasonable comment to me, and not an objection to the finding.

Re: New study provides evidence that we need different drugs for men and women

#23

Post by tropdrop »

xeeeeeeeeeeenu wrote: post #15

The mechanism of action of analgesic drugs is very simple and well-understood. Considering the fact that the very same painkillers that humans use are effective on drastically different organisms, such as snails or crustaceans, I find it extremely unlikely that gender plays any significant role in their effectiveness. To be honest, it feels like this study was politically motivated.

The study is not disproving the efficacy of analgesic drugs of most organisms - only suggesting that not all pain mechanisms are well understood, which is a reasonable suggestion. Further, given our (US) current opioid epidemic and death count, I find the implication that "we don't need to study other pain-relieving drugs" dubious.

Finally, do note that most analgesics have harmful side effects (acetaminophen - liver, NSAID - stomach bleeding). Does that mean they do not work as pain killers? No. But when a large portion of 50% of the population needs to take them for several days for 1 week of every month, we have every market incentive to look for other pain-relieving solutions.

Just for a personal example, my mother's period pain warranted a prolonged combination of NSAIDs and acetaminophen all her life, for 1 week of every month. Had the pills been more effective, she might have needed fewer of them in a sitting, and may not be dealing with the stomach bleeding she has now.

Re: New study provides evidence that we need different drugs for men and women

#25

Post by Simon_says »

It will be good to figure out which drugs work for which genders so people suffering from pain will know which gender to identify as for the most effective pain relief. If we find that some drugs are more effective on animal models, we can encourage otherkin.

Re: New study provides evidence that we need different drugs for men and women

#26

Post by adrianN »

Simon_says wrote: post #25

It will be good to figure out which drugs work for which genders so people suffering from pain will know which gender to identify as for the most effective pain relief. If we find that some drugs are more effective on animal models, we can encourage otherkin.

You're confusing sex and gender.

Re: New study provides evidence that we need different drugs for men and women

#27

Post by Frqy3 »

m463 wrote: post #3

I was told that the clinical studies of birth control pills were done on male subjects.

Not testing on women, and particularly avoiding pregnant women, is how to end up with another thalidomide case.

Sure, you wouldn't want pregnant women to be amongst your first field test subjects. But you do want them to be included as part of the carefully monitored testing period, rather than wait until the drug goes commercial and there is not the same focus on looking for and collecting data on side effects.

Re: New study provides evidence that we need different drugs for men and women

#28

Post by Simon_says »

adrianN wrote: post #26
Simon_says wrote: post #25

It will be good to figure out which drugs work for which genders so people suffering from pain will know which gender to identify as for the most effective pain relief. If we find that some drugs are more effective on animal models, we can encourage otherkin.

You're confusing sex and gender.

But I identify as someone who doesn't confuse sex and gender.

Re: New study provides evidence that we need different drugs for men and women

#29

Post by anon12345690 »

adrianN wrote: post #26
Simon_says wrote: post #25

It will be good to figure out which drugs work for which genders so people suffering from pain will know which gender to identify as for the most effective pain relief. If we find that some drugs are more effective on animal models, we can encourage otherkin.

You're confusing sex and gender.

the people who change genders disagree

Re: New study provides evidence that we need different drugs for men and women

#30

Post by anon12345690 »

jonnybgood wrote: post #11
djsumdog wrote: post #9

Earlier quoted context omitted.

I realize this is meant as a joke, but in all seriousness, this does go against some of the absurdist grain of what we're seeing today. No one should be bullied or made fun of for their beliefs, but the idea that biological sex is some type of subjective personal choice is ideological; even religious. Papers like this could seriously face censorship in the future, and it's something we need to address and take seriou…

> No one should be bullied or made fun of for their beliefs, but the idea that biological sex is some type of subjective personal choice is ideological; even religious. You’re confusing sex with gender.

the people who change gender disagree, there are tons of trans people and supporters who dont believe in biological sex
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