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Herpes Virus Reactivation in Astronauts During Spaceflight

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Re: Herpes Virus Reactivation in Astronauts During Spaceflight

#91

Post by bojo »

freeflight wrote: post #68
nabla9 wrote: post #22

Earlier quoted context omitted.

I would humbly suggest submarine crews as control group. Canned air, tight space, weird sleep cycles, noise and artificial light. Submarine crews are even more isolated because they can't contact families while underway.

I'd imagine this whole "being strapped to a ton of explosives and using them to fly" moment is a tad bit more extreme and stressful than a submarine dive. After that, they both have similar constant stress factors, but imho the launch alone is probably way more than what anybody on a submarine would go through.

The crew quarters are literally between the missile launch tubes, which sure they aren’t exploding under you, but still.

Re: Herpes Virus Reactivation in Astronauts During Spaceflight

#92

Post by tomcam »

degenerate wrote: post #29
fixermark wrote: post #2

Interesting to me personally because I'd never heard before that HSV-1 reactivation was stress-linked.

If you ever had chicken pox, high stress can re-activate the dormant virus, and it reactivates as "shingles". There is a vaccine that came out a few years ago to suppress it from happening.

Had chicken pox in my 30s. Not good. The shingles vaccine isn’t expensive, thank heaven. It’s a quarter century later and my mom got shingles at about this age…

Re: Herpes Virus Reactivation in Astronauts During Spaceflight

#93

Post by steve1977 »

taneq wrote: post #67
nabla9 wrote: post #22

Earlier quoted context omitted.

I would humbly suggest submarine crews as control group. Canned air, tight space, weird sleep cycles, noise and artificial light. Submarine crews are even more isolated because they can't contact families while underway.

Also airline crews? They get to do their high-pressure job in lower-than-normal air pressure, they get shaken around in a tin can and their sleep schedules are shot to hell.

But they can at least leave their cabins every couple of hours for a a couple of hours or days.

Re: Herpes Virus Reactivation in Astronauts During Spaceflight

#94

Post by rincebrain »

degenerate wrote: post #29
fixermark wrote: post #2

Interesting to me personally because I'd never heard before that HSV-1 reactivation was stress-linked.

If you ever had chicken pox, high stress can re-activate the dormant virus, and it reactivates as "shingles". There is a vaccine that came out a few years ago to suppress it from happening.

AFAICT both the options for shingles vaccination are just variants on the chickenpox vaccine - one being more directly just a high dose of it.

This doesn't undermine anything you say, I'm just bemused at the lag time between the chickenpox vaccine (1984) and Zostavax (2006).

Re: Herpes Virus Reactivation in Astronauts During Spaceflight

#95

Post by SketchySeaBeast »

serf wrote: post #57
SketchySeaBeast wrote: post #53

Earlier quoted context omitted.

> I highly doubt that HSV-1 is anywhere near 60% in the pool of astronaut candidates. Disease presence is correlated: if you have one, you probably have another. Since lots of other diseases would already be disqualifying, adding HSV-1 to the checklist won't strike off very many potential astronauts. Dude, I've had cold sores since I was a child. There's no relationship between HSV-1 and other diseases.

>Dude, I've had cold sores since I was a child. There's no relationship between HSV-1 and other diseases. Repeated (chronic) bacterial or viral wounding doesn't result in increased cancer risks? I find that hard to believe.

>I highly doubt that HSV-1 is anywhere near 60% in the pool of astronaut candidates. Disease presence is correlated: if you have one, you probably have another. Since lots of other diseases would already be disqualifying, adding HSV-1 to the checklist won't strike off very many potential astronauts.

I took exception to the claim that having cold sores meant you were otherwise "diseased". Can it have long term effects? Yes, but I don't believe an increased long term cancer risk means you're not able to become an astronaut.

Re: Herpes Virus Reactivation in Astronauts During Spaceflight

#96

Post by craftyguy »

zeckalpha wrote: post #73
freeflight wrote: post #68

Earlier quoted context omitted.

I'd imagine this whole "being strapped to a ton of explosives and using them to fly" moment is a tad bit more extreme and stressful than a submarine dive. After that, they both have similar constant stress factors, but imho the launch alone is probably way more than what anybody on a submarine would go through.

Nuclear submarines?

I suspect that far more rockets have undergone rapid, unplanned disassembly than nuclear submarines. And when they do, the death rate is very high.

Re: Herpes Virus Reactivation in Astronauts During Spaceflight

#97

Post by iyereglory »

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Re: Herpes Virus Reactivation in Astronauts During Spaceflight

#98

Post by SketchySeaBeast »

morothy wrote: post #69
ekianjo wrote: post #61

Earlier quoted context omitted.

so are you saying that you have data to show correlation between HSV 1 and other diseases? Please share.

Herpes and Alzheimer's https://www.theatlantic.com/science/archive/2018/07/herpes-v... more on HN: https://hn.algolia.com/?query=herpes%20alzheimer&sort=byPopu...

HHV–6 is pointed out as causing the same issue - according to wikipedia HHV-6B is in pretty much every person.
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