By contrast, traditionally in science you're coming in with a hypothesis ahead of time about what variables predict what target. The goal is to come up with a model that is consistent with your hypothesis (and possibly some existing theory), and which can be applied generally, and which should need no tuning. For example, the very simple model for Beer's Law-- absorbance vs concentration. That is a law that will apply in every other circumstance, but if modern ML methods had been applied, the scientist might have chosen the model with a slightly better score but which includes nonsense variables in addition to concentration.
All that to say, it seems to me the problem stems from scientists' lack of hypotheses at the outset of a project, and/or the understandable desire to get the best bang for their buck out of an experiment by measuring dozens of variables at once and hoping the magic of ML can find a hypothesis for them.
Hope that made sense.