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New pill can deliver insulin

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Re: New pill can deliver insulin

#101
Is diabetes curable with gene therapy? I'm surprised we can cure hemophilia with gene therapy but not diabetes. Is it impossible to get your pancreas to create insulin naturally because it's missing something vital?

[1] https://www.nih.gov/news-events/nih-research-matters/gene-th...

Re: New pill can deliver insulin

#102
Breakthrough like this needs to be designed so that people can afford it. It just becomes burdensome (and depressing) for people who may need it and find the cost out of reach.

On the other hand, given that treating diabetes is more costly to the society in general (although more profitable for the pharma companies), shouldn't there be more research to ensure people don't get into the trap of becoming diabetic? One reason people become Type 2 diabetic is that they are completely unaware that their lifestyle and food they are eating are slowly creeping in to make them suffer with this disease. Healthy people only know about them becoming diabetic because the cycle to get your blood sugar measured (A1C Hemoglobin) is too far in between (annual checkups). If a person is more aware of his/her blood sugar levels at shorter intervals, then a proactive approach can be made so that the person can do changes that will help prevent diabetes.

Re: New pill can deliver insulin

#103
post #75
post #26

Earlier quoted context omitted.

> I don't know a single diabetic who cares about injections and blood sugar tests. I'm diabetic and the sole reason I don't check my blood sugar (unless I think something is drastically out of whack) is that it takes me upwards of 30 minutes to do a finger prick for testing. My anxiety skyrockets and nothing I do can tell me that it's not going to be excruciating. Most of the time I end up having my wife do it, which…

I was on a CGM (Dexcom) for about 3 months until my new insurance would not cover it. Even though it's convenient, it comes with its own set of problems - having to restock every month (with copays) got tiring and somewhat expensive compared to strips. I also had false low reads a number of times. And the amount of wasted plastic (the applicator gun) is concerning if you are environmentally conscious. As for lancets,…

I third the FastClix. My biggest problem is that they charge about 10x the cost of the cheap lancets. I also reuse them to keep the cost down.

Re: New pill can deliver insulin

#104

Breakthrough like this needs to be designed so that people can afford it. It just becomes burdensome (and depressing) for people who may need it and find the cost out of reach. On the other hand, given that treating diabetes is more costly to the society in general (although more profitable for the pharma companies), shouldn't there be more research to ensure people don't get into the trap of becoming diabetic? One r…

BigPharma is a business and has no incentive to prevent or cure disease but to make sure the patient remains a customer

Re: New pill can deliver insulin

#105
post #34
post #16

Earlier quoted context omitted.

What doctors and researchers get wrong about diabetes is that pin-pricks and injections are not even remotely bad. I don't know a single diabetic who cares about injections and blood sugar tests. You get used to that within the first week of diagnosis. No, the unpleasant part of being diabetic is having to live every second of your life as an act of weighing how what you're currently doing is going to affect your blo…

Yeah. I've been T1D since I was 13 (now 30) and I can't even imagine what it's like to live without it. It's literally a constant thread in my mind, every waking moment, and a few times a week while I sleep. I carry glucose tablets and a few granola bars on me, and you're right about carrying insulin. Am I likely to eat on this trip, or can I leave it at home so it doesn't spoil? I once failed to bring my insulin on…

Also a T1D here. I once had my test meter go bad on an international trip; by the time I realized it wasn't working I was on a deserted island that was an about a 4-hour boat ride away from the nearest pharmacy, which was closed.

Talk about stress levels going through the roof!

Re: New pill can deliver insulin

#106
post #93
post #85

Earlier quoted context omitted.

You mean diabetes type 2. It's tiring to keep getting suggestions of how to change diet when my body absolutely needs insulin from an external source. Further, while people may be able to reverse type 2, they still need insulin until they actually get there. So research into insulin delivery is relevant to all diabetics. Also there are many ways of reducing carbohydrate intake. The diet you write about is just one of…

It is not just about carbohydrates.It is the healing by natural minerals vitamins from fruits and vegetables which cannot be replaced by supplements. There is a long science with research papers which cannot be explained here.

You’re retarded. Type I diabetics literally lack the machinery to produce insulin. When their disease is fully progressed there is nothing that produces to heal.

Go away retard.

Re: New pill can deliver insulin

#107
post #16

Earlier quoted context omitted.

What doctors and researchers get wrong about diabetes is that pin-pricks and injections are not even remotely bad. I don't know a single diabetic who cares about injections and blood sugar tests. You get used to that within the first week of diagnosis. No, the unpleasant part of being diabetic is having to live every second of your life as an act of weighing how what you're currently doing is going to affect your blo…

I am type 1.5 and disagree with both parts of your post. While learning to use them routinely only takes a few days, needles and lancets do bother people for anxiety reasons, but also for physiological reasons. Lancet areas develop callouses, can have blood flow issues and in more advanced stages of diabetics can risk infections/damage. Injection sites go bad over time or appear to; right now I am dealing with an iss…

"Hypoglycemia has the advantage of being treated with glucose tablets, which don’t spoil and can be stashed everywhere."

Umm... glucose tablets do in fact spoil. I've never seen an unopened bottle spoil, but once they are opened they can spoil over time mostly from the humidity. I found this out the hard way.

Re: New pill can deliver insulin

#108

Earlier quoted context omitted.

I am type 1.5 and disagree with both parts of your post. While learning to use them routinely only takes a few days, needles and lancets do bother people for anxiety reasons, but also for physiological reasons. Lancet areas develop callouses, can have blood flow issues and in more advanced stages of diabetics can risk infections/damage. Injection sites go bad over time or appear to; right now I am dealing with an iss…

"Hypoglycemia has the advantage of being treated with glucose tablets, which don’t spoil and can be stashed everywhere." Umm... glucose tablets do in fact spoil. I've never seen an unopened bottle spoil, but once they are opened they can spoil over time mostly from the humidity. I found this out the hard way.

Sure, I replace them periodically. They don’t spoil quickly, though, in the sense that insulin spoils just from being outside too long. You don’t have to curtail your physical activity to avoid hypoglycemia because glucose is portable and durable.

Re: New pill can deliver insulin

#109

Is diabetes curable with gene therapy? I'm surprised we can cure hemophilia with gene therapy but not diabetes. Is it impossible to get your pancreas to create insulin naturally because it's missing something vital? [1] https://www.nih.gov/news-events/nih-research-matters/gene-th...

type 1 diabetes is an autoimmune disease where your immune system kills the beta cells that live on the pancreas. you can get donar beta cells that will work but your immune system will just kill them off again. This only works with immunosuppresents which will cause 10x more issues than just taking insulin.

Re: New pill can deliver insulin

#110
post #26
post #16

Earlier quoted context omitted.

What doctors and researchers get wrong about diabetes is that pin-pricks and injections are not even remotely bad. I don't know a single diabetic who cares about injections and blood sugar tests. You get used to that within the first week of diagnosis. No, the unpleasant part of being diabetic is having to live every second of your life as an act of weighing how what you're currently doing is going to affect your blo…

> I don't know a single diabetic who cares about injections and blood sugar tests. I'm diabetic and the sole reason I don't check my blood sugar (unless I think something is drastically out of whack) is that it takes me upwards of 30 minutes to do a finger prick for testing. My anxiety skyrockets and nothing I do can tell me that it's not going to be excruciating. Most of the time I end up having my wife do it, which…

Have you talked with a mental health professional about your anxiety? They may be able to help you with techniques to reduce it.
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