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New pill can deliver insulin

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91–100 of 260 posts

Re: New pill can deliver insulin

#91
post #21

Inhalable insulin was a total failure, even though it worked. I don't expect this to succeed where inhalable insulin failed.

First time I heard about inhalable insulin! Indeed it's unclear what the pills could offer over this.

Re: New pill can deliver insulin

#92
post #16
post #4

> Once ingested, water dissolves a disk of sugar, using a spring to release a tiny needle made up almost entirely of freeze-dried insulin. The needle is injected into the stomach — which the patient can’t feel, owing to a lack of pain receptors in the stomach. Once the injection has occurred, the needle can break down in the digestive tract. That's some pretty impressive ingenuity. Also sounds kinda terrifying if the…

What doctors and researchers get wrong about diabetes is that pin-pricks and injections are not even remotely bad. I don't know a single diabetic who cares about injections and blood sugar tests. You get used to that within the first week of diagnosis. No, the unpleasant part of being diabetic is having to live every second of your life as an act of weighing how what you're currently doing is going to affect your blo…

I’m not diabetic but just reading your comment is making me feel queasy and on edge.

Re: New pill can deliver insulin

#93
post #85
post #67

Plant based diet can reverse diabetes ( I and II ). For type I milk products need to be stopped. Take 1% of your bodyweight as fruits. Take 1 % of your body weight as Raw ( uncooked ) vegetables. Take 10% of that vegetable quota as green leafy vegetables. Based on China Study by Colin Campbell. e.g. weight 150 pounds 1.5 pounds fruits before 1 pm 1.5 pounds raw vegetables for the day If you are still hungry you can e…

You mean diabetes type 2. It's tiring to keep getting suggestions of how to change diet when my body absolutely needs insulin from an external source. Further, while people may be able to reverse type 2, they still need insulin until they actually get there. So research into insulin delivery is relevant to all diabetics. Also there are many ways of reducing carbohydrate intake. The diet you write about is just one of…

It is not just about carbohydrates.It is the healing by natural minerals vitamins from fruits and vegetables which cannot be replaced by supplements. There is a long science with research papers which cannot be explained here.

Re: New pill can deliver insulin

#94
post #75
post #26

Earlier quoted context omitted.

> I don't know a single diabetic who cares about injections and blood sugar tests. I'm diabetic and the sole reason I don't check my blood sugar (unless I think something is drastically out of whack) is that it takes me upwards of 30 minutes to do a finger prick for testing. My anxiety skyrockets and nothing I do can tell me that it's not going to be excruciating. Most of the time I end up having my wife do it, which…

I was on a CGM (Dexcom) for about 3 months until my new insurance would not cover it. Even though it's convenient, it comes with its own set of problems - having to restock every month (with copays) got tiring and somewhat expensive compared to strips. I also had false low reads a number of times. And the amount of wasted plastic (the applicator gun) is concerning if you are environmentally conscious. As for lancets,…

I second the AccuCheck fastclix. The needles are silicon coated so they don't tear tissues -- so very little pain. I hated using the other brands of lancets. The needles are encased in a cartridge, so you can throw them away in a trash can and don't have to worry about anyone getting a stick or punching through a trash bag.

Re: New pill can deliver insulin

#95
post #17

For the case of T2D, eating fewer carbs may be more effective than later reducing it with expensive insulin and fancy MIT pills. I often hear good stuff about these guys: https://www.virtahealth.com/ (no affiliation) edit: clarify that Virta is treating T2D primarily.

It's a good point too that taking insulin is associated with greater risk of obesity and further worsening of T2D in the long term. So dietary interventions (which are experiencing great success -- both Virta and also the work of Dr. Jason Fung et co at Intensive Dietary Management) -- often produce much better outcomes for type two than insulin (naturally no one should go off insulin without being under the guidance of a doctor of course)

Re: New pill can deliver insulin

#96
post #16

Earlier quoted context omitted.

What doctors and researchers get wrong about diabetes is that pin-pricks and injections are not even remotely bad. I don't know a single diabetic who cares about injections and blood sugar tests. You get used to that within the first week of diagnosis. No, the unpleasant part of being diabetic is having to live every second of your life as an act of weighing how what you're currently doing is going to affect your blo…

I am type 1.5 and disagree with both parts of your post. While learning to use them routinely only takes a few days, needles and lancets do bother people for anxiety reasons, but also for physiological reasons. Lancet areas develop callouses, can have blood flow issues and in more advanced stages of diabetics can risk infections/damage. Injection sites go bad over time or appear to; right now I am dealing with an iss…

teaching other diabetics to be so preoccupied is dangerous to them because it increases the temptation to give up on the daily routines

^^ Sorry, this makes no sense at all. Maintaining a routine is one way to express a preoccupation with diabetes management!

Re: New pill can deliver insulin

#97
post #96

Earlier quoted context omitted.

I am type 1.5 and disagree with both parts of your post. While learning to use them routinely only takes a few days, needles and lancets do bother people for anxiety reasons, but also for physiological reasons. Lancet areas develop callouses, can have blood flow issues and in more advanced stages of diabetics can risk infections/damage. Injection sites go bad over time or appear to; right now I am dealing with an iss…

teaching other diabetics to be so preoccupied is dangerous to them because it increases the temptation to give up on the daily routines ^^ Sorry, this makes no sense at all. Maintaining a routine is one way to express a preoccupation with diabetes management!

I mean: there are a few things you need to do each day to manage diabetes. These are important. What you don’t need to do is worry about it between those times. If you convince someone they need to do too much to manage the disease, they’re more likely to give up on the whole thing.

Re: New pill can deliver insulin

#98
post #4

> Once ingested, water dissolves a disk of sugar, using a spring to release a tiny needle made up almost entirely of freeze-dried insulin. The needle is injected into the stomach — which the patient can’t feel, owing to a lack of pain receptors in the stomach. Once the injection has occurred, the needle can break down in the digestive tract. That's some pretty impressive ingenuity. Also sounds kinda terrifying if the…

I test my insulin willingly with no diabetes. One hard squat hurts way more Than either of those activities. I have actually teared up from hard lifts. Needles are just a nuisance. The real downside to beetus is having to think about it constantly, IMO. (And managing it for kids, who don’t have perspective on blood/needles)

~meditation or similar mental massaging seems to be key at one point. Avoiding the damages of constant stress is important.

Re: New pill can deliver insulin

#100
post #28

Earlier quoted context omitted.

Per a quick google <15% of type 2 diabetics use insulin. I would say this effects more type 1 diabetics than anything. Or are you trying to say peoples lifestyles are leading them to an autoimmune disease?

I'm saying Novo Nordisk produces insulin, and in doing so causes downward pressure on insulin prices thanks to basic economics. (When the supply of a good increases at the same level of demand, price falls.) This is true for both type 1 and type 2 diabetics. In Novo's case, they have two kinds of long-acting insulin analogue taken 1-2 times per day for both T1 and T2; they have to my knowledge the only ultra-long-act…

There are really 2 major makers of insulin Norvo and Elli and another that isnt near as popular, Apidra. Each insurance company has a 'preferred' where you only have 1 choice.

So, with that I dont feel like there really is any competition. A good step forward might be to disallow insurance companies from having 'preferred' brands.

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