Earlier quoted context omitted.
The 777 is still doing pretty well, isn’t it? I’ve never been in an A380, but I’ve flown the 747 and 787 and there was no real difference in the experience.
I'm surprised to hear you say that, since I find the two very different. 747s are much noisier (unless you're up top) and have less humidity & cabin pressure, making them materially less comfortable on long flights. Also, most airlines are now buying 787s and A350s instead of 777s.
How does increased cabin pressure make for increased comfort? Once your ears equalize, the only difference should be less oxygen available, which I’d think would make you feel better (albeit stupider).