On the other side, there is a definite shift towards "backendless" applications, where frontend talks directly to the DB, either via autogenerated ReST or GraphQL APIs or via proprietary tools like Cloud Firestore. This is good for MVPs.
Frameworks like React & Angular give you decent building blocks to create SPAs, but the learning curve & effort required to create ambitious applications is very high.
There is a proliferation of "Low Code" frameworks which allow you to design drag & drop UIs & connect them with APIs. But, it feels like going back to "RAD" tools for the late 90s which led to a lot of spaghetti code. Also, some of these are prohibitively expensive.
One noteworthy change is UI design products which are trying to produce the code from UI Mockups. Relatively primitive at this stage. A breakthrough here can definitely be a big productivity booster.
Another productivity booster is Cross-Platform frameworks. It's already here, tried & tested. We know the trade-offs well. It requires a huge amount of effort to create & maintain a cross-platform framework. Big companies are already tackling this.
Considering this background, what do you think will be a breakthrough innovation in programming which will enable programmers to deliver ambitious web/mobile apps at a very high speed.