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Guy Says He's the First Person to Attempt Editing His DNA with CRISPR

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Re: Guy Says He's the First Person to Attempt Editing His DNA with CRISPR

#3
2017 but also here's a bit of follow up on Josiah:

>So when Zayner saw Ascendance Biomedical’s CEO injecting himself on a live-stream earlier this month, you might say there was an uneasy flicker of recognition.

>Ascendance Bio soon fell apart in almost comical fashion. The company’s own biohackers—who created the treatment but who were not being paid—revolted and the CEO locked himself in a lab. Even before all that, the company had another man inject himself with an untested HIV treatment on Facebook Live. And just days after the pants-less herpes treatment stunt, another biohacker who shared lab space with Ascendance posted a video detailing a self-created gene therapy for lactose intolerance. The stakes in biohacking seem to be getting higher and higher.

>“Honestly, I kind of blame myself,” Zayner told me recently. He’s been in a soul-searching mood; he recently had a kid and the backlash to the CRISPR stunt in October had been getting to him. “There’s no doubt in my mind that somebody is going to end up hurt eventually,” he said.

https://www.theatlantic.com/science/archive/2018/02/biohacki...

Re: Guy Says He's the First Person to Attempt Editing His DNA with CRISPR

#4
"I want to live in a world where people get drunk and instead of giving themselves tattoos, they’re like, ‘I’m drunk, I’m going to CRISPR myself."

Ok, scary thought already. But, casting aside all the safety concerns, how many attributes would someone in general want to change as an adult? You can't change your height, you can't change your hair color, you can't change your eyes. Is a myostatin-inhibitor going to be the "killer app" of DIY Crispr, so we can all look like a Belgian Blue cow?

Re: Guy Says He's the First Person to Attempt Editing His DNA with CRISPR

#5
Regardless of how well this particular case works, I'm in favor of people being able to modify their bodies as they see fit. If he wants to become more muscular, morbidly obese, or ten feet tall, that's his right.

Unfortunately, I could see things like this becoming illegal solely because they help people play sports too well.

Re: Guy Says He's the First Person to Attempt Editing His DNA with CRISPR

#7
This shouldn't be legal. If people fuck themselves up the worst case isn't just them dying, they can accidently unleash a virus. Pretty unlikely, but just the smallest possibility is still too much when the outcome can be so bad.

It's not unreasonable that tinkering with dna will unleash some dormant retrovirus.

Re: Guy Says He's the First Person to Attempt Editing His DNA with CRISPR

#9
Transmissible CRISPR gene edits are not impossible (Paywall link below). Vectors for these edits probably aren't limited to injection. Which makes me wonder if the obsession over 3D printed firearms ought to share a bit of worryshare with do-it-youself genome editing.

https://www.genomeweb.com/gene-silencinggene-editing/paper-o...

Re: Guy Says He's the First Person to Attempt Editing His DNA with CRISPR

#10

Regardless of how well this particular case works, I'm in favor of people being able to modify their bodies as they see fit. If he wants to become more muscular, morbidly obese, or ten feet tall, that's his right. Unfortunately, I could see things like this becoming illegal solely because they help people play sports too well.

I agree, but there are externalities. Medical care resulting from personal choices should be paid by the risk-taking individual (or the research firm, if it's a sponsored experiment), rather than society or other people in the insurance pool.
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