Sure, the high salt concentration kills sea life for a couple hundred meters around where the waste comes out, but compared to the total size of the ocean, I'd imagine the affected area would be TINY. Once you get to a larger area it'd be totally diluted by the normal salinity seawater. Why don't you just build a pipeline to put the dead spot a couple miles away from shore, far away from economically important beache…
That is what I intuitively thought, until I learnt that salinity in the Persian Gulf (a huge body of water connected to the ocean) is up significantly due to desalination. Salinity has risen 50% over the last two decades. See e.g. https://financialtribune.com/articles/people-environment/434...
The two competing theories seem to be 1. desalination and 2. climate change causing excessive evaporation.