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Consumption of a dark roast coffee blend reduces DNA damage in humans

ncbi.nlm.nih.gov

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Re: Consumption of a dark roast coffee blend reduces DNA damage in humans

#2
Quick googling indicates that tea has similar effect https://www.ncbi.nlm.nih.gov/pubmed/24585444 (very small study but effect size is good), another study is https://academic.oup.com/jn/article/138/8/1567S/4750818

What are the common ingredients in coffee and tea except caffeine?

EDIT:

It seems like black tea also, although I can't make sense of the biological jargon. https://pubs.acs.org/doi/abs/10.1021/jf010875c

Re: Consumption of a dark roast coffee blend reduces DNA damage in humans

#3
>Our results indicate that regular consumption of a dark roast coffee blend has a beneficial protective effect on human DNA integrity in both, men and women.

What they established was that drinking water damages DNA. When they drank coffee there wasn't as much damage. It's a stretch to say that coffee is providing a protective effect though.

Without denigrating anyone, it's a bad study.

What was the chemical breakdown of the water? Was it tap water? Distilled? Bottled? Spring? etc.

A better designed study would have groups drinking different kinds of water. Was the fact that the water was boiled (in the coffee) providing the protective effect? i.e removing toxins etc, did the kettle they use have a filter that processed the water, whereas the water was drunk straight from a tap etc.

Coffee is great though!

Re: Consumption of a dark roast coffee blend reduces DNA damage in humans

#4
post #3

>Our results indicate that regular consumption of a dark roast coffee blend has a beneficial protective effect on human DNA integrity in both, men and women. What they established was that drinking water damages DNA. When they drank coffee there wasn't as much damage. It's a stretch to say that coffee is providing a protective effect though. Without denigrating anyone, it's a bad study. What was the chemical breakdow…

[deleted]

Re: Consumption of a dark roast coffee blend reduces DNA damage in humans

#6
post #2

Quick googling indicates that tea has similar effect https://www.ncbi.nlm.nih.gov/pubmed/24585444 (very small study but effect size is good), another study is https://academic.oup.com/jn/article/138/8/1567S/4750818 What are the common ingredients in coffee and tea except caffeine? EDIT: It seems like black tea also, although I can't make sense of the biological jargon. https://pubs.acs.org/doi/abs/10.1021/jf010875c

Both contain tannins. I am not suggesting that these are the cause of the benefits observed in the study.

Re: Consumption of a dark roast coffee blend reduces DNA damage in humans

#7
post #2

Quick googling indicates that tea has similar effect https://www.ncbi.nlm.nih.gov/pubmed/24585444 (very small study but effect size is good), another study is https://academic.oup.com/jn/article/138/8/1567S/4750818 What are the common ingredients in coffee and tea except caffeine? EDIT: It seems like black tea also, although I can't make sense of the biological jargon. https://pubs.acs.org/doi/abs/10.1021/jf010875c

Both contain tannins. I am not suggesting that these are the cause of the benefits observed in the study.

Beer contains tannins also. Not that I need any extra excuse..

Re: Consumption of a dark roast coffee blend reduces DNA damage in humans

#8
post #3

>Our results indicate that regular consumption of a dark roast coffee blend has a beneficial protective effect on human DNA integrity in both, men and women. What they established was that drinking water damages DNA. When they drank coffee there wasn't as much damage. It's a stretch to say that coffee is providing a protective effect though. Without denigrating anyone, it's a bad study. What was the chemical breakdow…

Coffee contains water. If water is harmful, coffee will be just as harmful unless it has protective effects.

In any case, you can't say they "established that drinking water damages DNA" and then go on to argue that they should establish it with another study about water.

Re: Consumption of a dark roast coffee blend reduces DNA damage in humans

#9
post #8
post #3

>Our results indicate that regular consumption of a dark roast coffee blend has a beneficial protective effect on human DNA integrity in both, men and women. What they established was that drinking water damages DNA. When they drank coffee there wasn't as much damage. It's a stretch to say that coffee is providing a protective effect though. Without denigrating anyone, it's a bad study. What was the chemical breakdow…

Coffee contains water. If water is harmful, coffee will be just as harmful unless it has protective effects. In any case, you can't say they "established that drinking water damages DNA" and then go on to argue that they should establish it with another study about water.

It's not clear to me that the control group drank 500ml of boiled water.

If they're drinking cold tap water, it could be that the act of boiling the water yields the desired effect. If they're drinking bottled water (and if the instructions said "drink 500ml of water", this would be my first inclination) then maybe the DNA damage is being caused by plastic that's leaching into the water as opposed to any preventative effect in coffee.

Re: Consumption of a dark roast coffee blend reduces DNA damage in humans

#10

If we had even 1 honest meta-analysis for every 10 trials like this, well, we'd know more than we do now. Small trials with inconsistent/poor designs are the bane of medical science. That said, I drink dark roast so this study must be true.

Here is nice meta study of coffee and cancer risk (dna damage and cancer are probably linked).

https://www.nature.com/articles/srep33711

> coffee intake was associated with reduced risk of oral, pharynx, liver, colon, prostate, endometrial cancer and melanoma and increased lung cancer risk.

(Heh. Smokers drink nearly twice as much coffee as non-smokers. Smoking increases caffeine metabolism. I think this explains the lung cancer risk)

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