The pill causes a lot of problems later in life; something only discovered recently, since it is a relatively new creation. It also changes mate preferences, and what that means for the future is unknown.
> The pill causes a lot of problems later in life; something only discovered recently, since it is a relatively new creation. Could you be specific here (ideally with links)?
Does the contraceptive pill alter mate choice in humans? https://www.ncbi.nlm.nih.gov/pubmed/19818527
Oral contraceptive use in women changes preferences for male facial masculinity and is associated with partner facial masculinity https://www.ncbi.nlm.nih.gov/pubmed/23528282
Edit: Oops, I posted studies linked to mate choice and not issues later in life as you requested. Arguably, choosing the wrong mate could be considered an issue in the long term, but I assume you referred specifically to medical ones.