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Compass Pathways has set itself up to be the first legal provider of psilocybin

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Re: Compass Pathways has set itself up to be the first legal provider of psilocybin

#61

Post by CharlesW »

creaghpatr wrote: post #52
basseq wrote: post #35

This is an interesting article for HN. It's spun as a negative, using terms like "threatening", "monopoly", "controversial", and "retribution". You could write it the other way, where an immigrant-founded[1] startup is disrupting the mental health industry. Frankly, most of this seems like par for the course. Of course the company is seeking to push their product to market and commercial viability--and the potential…

Is it a good or bad thing that it is immigrant-founded?

Not the OC, but I'm guessing they mentioned it as a likely contributor to the "hand-wringing".

Re: Compass Pathways has set itself up to be the first legal provider of psilocybin

#62

Post by atomical »

basseq wrote: post #35

This is an interesting article for HN. It's spun as a negative, using terms like "threatening", "monopoly", "controversial", and "retribution". You could write it the other way, where an immigrant-founded[1] startup is disrupting the mental health industry. Frankly, most of this seems like par for the course. Of course the company is seeking to push their product to market and commercial viability--and the potential…

There has to be a profit motive to get something to market. There have been 18 years of small studies on Ketamine for TRD with little progress.

Re: Compass Pathways has set itself up to be the first legal provider of psilocybin

#63

Post by mountainplus »

Very well written and extensive longform!

I found the link at the end also very interesting.

https://files.csp.org/open.pdf ("STATEMENT ON OPEN SCIENCE AND OPEN PRAXIS WITH PSILOCYBIN, MDMA, AND SIMILAR SUBSTANCES")

It is not something I have heard about before but is something that is very calming to read and know.

Re: Compass Pathways has set itself up to be the first legal provider of psilocybin

#64

Post by ada1981 »

atomical wrote: post #62
basseq wrote: post #35

This is an interesting article for HN. It's spun as a negative, using terms like "threatening", "monopoly", "controversial", and "retribution". You could write it the other way, where an immigrant-founded[1] startup is disrupting the mental health industry. Frankly, most of this seems like par for the course. Of course the company is seeking to push their product to market and commercial viability--and the potential…

There has to be a profit motive to get something to market. There have been 18 years of small studies on Ketamine for TRD with little progress.

Unless you look at the other psychedelic with breakthrough status - MDMA, which Rick Doblin has brought through clinical trials as a non-profit.

Doblin has no profit motive and is stoked with his $70k a year salary. His goal is changing culture, that is his motive.

Re: Compass Pathways has set itself up to be the first legal provider of psilocybin

#65

Post by elcomet »

RankingMember wrote: post #53
elcomet wrote: post #25

Earlier quoted context omitted.

I removed the addictive part. This substance can have dangerous side-effects and bring you to the hospital, so it doesn't need to be addictive to hurt yourself.

> You are harming your family and friends by harming yourself. What of drinking alcohol? Eating too much food? Riding a bike without a helmet? Taking an antidepressant with known potentially dangerous side effects? Going outside without a jumpsuit made out of Nerf foam? At what point do you get to live your life for yourself instead of avoiding doing things you think others might not want you to do?

Of course. The point is that there is a scale of dangerousness. What are the odds of getting an accident riding a bike vs taking drugs like these ?

I think jumpsuits should be forbidden for the same reason, but that's just a personal opinion.

Re: Compass Pathways has set itself up to be the first legal provider of psilocybin

#66

Post by ada1981 »

atomical wrote: post #56
nyolfen wrote: post #2

if they're trying to monopolize psilocybin, they probably should have chosen something that isn't replicable by a teenager with access to a pressure cooker and a pasture

If psilocybin has some success in early clinical trials then companies will begin work on metabolites and similar compounds that purportedly have less side effects. That is what is happening with Ketamine right now.

What people seem to miss is that it’s the psychedelic experience itself that holds the healing potential.

We most likely won’t see a pill derived from mushrooms that cures depression but doesn’t get you high.

The altered state of conciousness is the thing.

Re: Compass Pathways has set itself up to be the first legal provider of psilocybin

#67

Post by CharlesW »

dsfyu404ed wrote: post #57
creaghpatr wrote: post #52

Earlier quoted context omitted.

Is it a good or bad thing that it is immigrant-founded?

You'll be hard pressed to find people in the US who think that someone (legally) immigrating to the US and starting a business is a bad thing.

You'd think, especially with U.S. population growth and fertility rates being so low.

In reality, the current administration is actively working to reduce legal immigration as well.[1][2] Although the policies are opposed by most, it's not difficult to find people who support reducing legal immigration as well.

[1] https://en.wikipedia.org/wiki/Immigration_policy_of_Donald_T...

[2] https://www.cato.org/blog/house-gop-bill-cuts-legal-immigrat...

Re: Compass Pathways has set itself up to be the first legal provider of psilocybin

#68

Post by perfmode »

atomical wrote: post #62
basseq wrote: post #35

This is an interesting article for HN. It's spun as a negative, using terms like "threatening", "monopoly", "controversial", and "retribution". You could write it the other way, where an immigrant-founded[1] startup is disrupting the mental health industry. Frankly, most of this seems like par for the course. Of course the company is seeking to push their product to market and commercial viability--and the potential…

There has to be a profit motive to get something to market. There have been 18 years of small studies on Ketamine for TRD with little progress.

Believe it or not, some people just want to make the world a better place.

Profit motive _can_ help to motivate people if there is a lack of motivation. However, it is not true that there _must_ be profit motive.

Right now, there is no lack of motivation to get this stuff out there. It is the questionable government prohibition that is holding things back.

Re: Compass Pathways has set itself up to be the first legal provider of psilocybin

#69

Post by dragonwriter »

dsfyu404ed wrote: post #57
creaghpatr wrote: post #52

Earlier quoted context omitted.

Is it a good or bad thing that it is immigrant-founded?

You'll be hard pressed to find people in the US who think that someone (legally) immigrating to the US and starting a business is a bad thing.

> You'll be hard pressed to find people in the US who think that someone (legally) immigrating to the US and starting a business is a bad thing.

Then why do we keep hearing about Republicans introducing measures to reduce permitted legal immigration, especially outside of the employer-need-driven categories? Those politicians, or at least the audience they are catering to, certainly seems to think that people coming to the US for purposes other than to reduce existing firms labor costs are a bad thing.

Re: Compass Pathways has set itself up to be the first legal provider of psilocybin

#70

Post by jschwartzi »

atomical wrote: post #16
jessaustin wrote: post #3

This is a natural product. One can grow it in the basement of one's home. One can gather it where it grows wild. (Ask me how I know!) No user of this product has ever harmed anyone else as a result of using it. Any restrictions at all on this product could only ever be tyrannical. Let's not abide tyranny, ok?

The blind spot here is that no one really understands how it works or the long term implications. It may have a use for patients with treatment resistant medical conditions where the alternatives have failed or side-effects are intolerable. Why should healthy adults take this substance? Many of the so-called experts interviewed in Michel Pollan's new book took psilocybin and believed the experience revealed the inner…

I think it's disingenuous to argue from the stance that magical thinking is bad and should be prevented, and thus that the drug is bad and should be eliminated. I think you'd be surprised just how many functional people have magical beliefs and especially how many scientists and engineers do. The notion that a pattern of thought is dangerous and should be outlawed has probably done more harm to the world than "meta-magical thinking."
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