I posted about fusing Neanderthal brains to spiking neural networks here once. A HN poster threatened to get the Pope to stop me. https://news.ycombinator.com/item?id=18425194 You have no idea how much more powerful neurology is over machine learning.
(As for your fusing neural organoids to computers, there was a sci-fi story I read years ago that used this theme. There were human-level AIs that needed some integrated organic grey matter to perform some of their higher level functions. Wish I could remember what it was - although that description probably covers half a dozen stories by now.)