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Israeli scientists develop tissue implants that won't be rejected

israel21c.org

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Re: Israeli scientists develop tissue implants that won't be rejected

#3
post #2

The title is about "organs", but the article apparently refers to tissue transplants? No small feat, don't get me wrong, but isn't it a little misleading?

you're right, there is a difference between organs. Tissue make up organs just like amino acids would make proteins.

Here is a clear explanation:

The difference between cells, tissues and organs. A group of cells working together is defined as a tissue and several tissues working together comprise an organ*

source: https://www.merckmanuals.com/home/fundamentals/the-human-bod...

Re: Israeli scientists develop tissue implants that won't be rejected

#4
The title is totally misleading.

- The 'implants' are not organs.

- The cells being implanted are from the recipient, so they naturally won't be rejected.

If the headline were true at all, we'd be reading about this in one of the big journals.

Edit: changed transplant to implant

Re: Israeli scientists develop tissue implants that won't be rejected

#5
post #2

The title is about "organs", but the article apparently refers to tissue transplants? No small feat, don't get me wrong, but isn't it a little misleading?

Well they do talk about using the implanted tissue to regenerate organs, which is pretty cool. But it still doesn't seem to render the headline accurate.

Re: Israeli scientists develop tissue implants that won't be rejected

#6
post #4

The title is totally misleading. - The 'implants' are not organs. - The cells being implanted are from the recipient, so they naturally won't be rejected. If the headline were true at all, we'd be reading about this in one of the big journals. Edit: changed transplant to implant

>- The cells being implanted are from the recipient, so they naturally won't be rejected.

Well, they appear to have engineered a patient's own cells into stem cells which were then re-implanted into a patient(s).

>“We were able to create a personalized hydrogel from the materials of the biopsy, to differentiate fatty tissue cells into different cell types and to engineer cardiac, spinal cord, cortical and other tissue implants to treat different diseases,” said lead researcher Prof. Tal Dvir

>The researchers extracted a small biopsy of fatty tissue from patients, then separated its cellular and a-cellular materials. While the cells were reprogrammed to become induced pluripotent stem cells — able to make cells from all three basic body layers, so they can potentially produce any cell or tissue the body needs to repair itself — the extracellular material was processed to become a personalized hydrogel.

Re: Israeli scientists develop tissue implants that won't be rejected

#9
It seems to me that the main advancement here is that the native extracellular matrix is being re-seeded with differentiated stem cells, as opposed to ordinary tissue engineering which uses a manufactured ECM or tissue transplants, which do not involve making stem cells.

There’s still a long way to go before organs can be engineered, even with this tech. We will need much finer control over the delivery of differentiating signal factors for pluripotent stem cells as well as ECM structure.

Re: Israeli scientists develop tissue implants that won't be rejected

#10
Israel is capable of conducting bleeding edge science in many fields. Their results are not published or reported on at the rate and level that would be justified.

You have most certainly come across and used things that has an Israeli origin without knowing.

One product, that sadly Google bought for a huge amount of money, is Waze, developed by Israelis.

Keep up the good work!

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