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A Blue Pill Is Stopping HIV, World-First Study Shows

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Re: A Blue Pill Is Stopping HIV, World-First Study Shows

#5
post #3

Graph seems to be comparing 6 months of 2018 with full years before that which would vastly overstate the decline.

This is misleading to the point that I would consider this lying to the audience. It's just wrong to convey the data in this way. The note below the graph does not make this OK.

If anybody is interested in the actual data, I think the data is pulled from "NSW HIV Surveillance Data Reports": https://www.health.nsw.gov.au/endinghiv/Pages/tools-and-data...

Re: A Blue Pill Is Stopping HIV, World-First Study Shows

#6
post #4

Developed by Gilead, the same company that created the Hep-C cure Sovaldi. Some kick-ass work there.

Have been googling Solvadi. Wow, curable hepatitis c is a big achievemt. But it‘s insanely expensive. It has to be taken daily for at least 12 weeks, with each pill costing 400€! The chance of curing is at 90%.

Re: A Blue Pill Is Stopping HIV, World-First Study Shows

#7
post #6
post #4

Developed by Gilead, the same company that created the Hep-C cure Sovaldi. Some kick-ass work there.

Have been googling Solvadi. Wow, curable hepatitis c is a big achievemt. But it‘s insanely expensive. It has to be taken daily for at least 12 weeks, with each pill costing 400€! The chance of curing is at 90%.

That sounds pretty inexpensive. It looks like the previous standard of care cost $10-15,000 and wasn't generally curative. Meanwhile, the long-term cost of a progressing hep-c infection is quite high.

Re: A Blue Pill Is Stopping HIV, World-First Study Shows

#8
The effectiveness of the tenofovir and emtricitabine combination is hard to overstate. Other studies show almost 100% prevention of infection; to my knowledge there have only been two recorded infections in people who were reliably taking PReP, both of which were due to unusual, rare mutations.

This sort of thing is a step change for vulnerable populations; hopefully it ends up being widely accessible. The combination of this and aggressive testing and treatment reigimes means that there’s a real possibility of getting close to zero new HIV infections in Western countries.

Re: A Blue Pill Is Stopping HIV, World-First Study Shows

#9
For me the biggest surprise in the article is that there are 180,000 men in the United States on Prep. Given a back of the envelope calculation of 4.8m out gay men in America (3% of population) that means adoption is itself around 3%.

Somehow I imagined truvada was more widey adopted but perhaps it is just heavily marketed on the east coast.

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