Earlier quoted context omitted.
How well does the inverse works - running VMs in OpenBSD to use Windows, Linux? Is it for example possible to run Virtualbox with good performance in OpenBSD? I'm tempted at using OpenBSD as OS, but need to run things like MS Office. A VM is probably the easiest way to do that.
There is an OpenBSD-specific hypervisor (vmm) in recent releases. I cannot comment on whether it is suitable for running VMs at this time.
QEMU is available in packages/ports, though; while almost certainly slow, it's a start. VirtualBox on Linux requires a kernel module, so unless someone manages to port that to OpenBSD (which would translate to adding it to OpenBSD's kernel, which doesn't support loadable kernel modules anymore), that one probably ain't an option.