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Recovering Emotions After 24 Years on Antidepressants

madinamerica.com

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Re: Recovering Emotions After 24 Years on Antidepressants

#141
post #51

Earlier quoted context omitted.

> I hope big pharma comes up with something else than benzos and SSRIs for anxiety, so that I can be relieved from the task of living my life spiting anxiety 70% of the day. Have you tried psilocybin mushrooms or DMT? I'd been on meds for years treating depression and anxiety. A few mushroom and DMT experiences have basically cured my depression and anxiety and opened up a whole new way of looking at things.

Yeah, I have used psilocybin mushrooms, DMT, and MDMA (and marihuana as well) before I went to seek professional help (or, rather, after I was disappointed with a previous professional endeavour and discredited the psych scientific community as a whole). After that, I tried the psychiatrist route (got a prescription) and eventually tried chronic gaming and alcoholism. None of that helped. Until I once more went via t…

It's sometimes not enough to simply use psychedelics. A lot has to do with the way you use them, with what intention, in what context, with whom, and how you follow up on and integrate your experience.

Plenty (most?) people take psychedelics without any kind of therapeutic or constructive intention -- they take them to party, to escape, as an antidote for boredom, etc. It's not surprising that such use of these powerful substances could have undesirable or even very negative effects -- though sometimes even such arguably reckless use still produces positive results.

Use of psychedelics in therapeutic and healing contexts tends to be very different. The intention tends to be very different, with a focus on healing or on a specific illness, symptom, or problem that the individual suffers from. There is often serious preparation for the journey, ranging from ways of purifying oneself (for psychedelic use in shamanic or other sacred contexts), to sessions of therapy (when this has been done in Western medical contexts).

The actual trips themselves also tend to be handled quite differently in healing/therapeutic contexts from recreational ones. In recreational contexts, people often do it at parties, with the lights on, or maybe watching movies, or maybe sometimes outside in nature. In therapeutic/healing context, the lights tend to be very low or off, sometimes blindfolds are used, and the focus internal. Music is often carefully selected to guide the journey. Sometimes people are asked to look at photos of loved one they've brought with them for this purpose. If things go wrong, trained support is available, and instructions are given on how to the experience in a constructive way, while in recreational settings the support is minimal and usually untrained, if it exists at all.

After the experience, the recreational user is usually on their own in terms of integrating and making sense of the experience, while in medical contexts there are often followup therapy sessions with trained professionals who can help in making sense of and constructively using whatever was uncovered during the trip, and perhaps the scheduling of further experiences with modified dosage, if needed.

I have no idea how your own psychedelic experiences were, but if they were more of the recreational kind, I am not very surprised that you didn't get much out of them.

Re: Recovering Emotions After 24 Years on Antidepressants

#142
post #139

Earlier quoted context omitted.

The thing you're missing is that it is learned insecurity that is associated with the biochemical changes, and that by doing the work to unlearn the insecurity as the author did you can reverse the biochemical changes. You can't make the statement that the biochemical changes are the cause of the insecurity, only that they are associated with it. And that's very important, because an "if-then" statement does not impl…

Some people can change to some degree, some can’t. Some people for example can recover from PTSD with time and talk therapy, and if you insist on others doing that they’ll end up killing themselves. Not taking medication is just as much of a fallacious “one-size-fits-all” solution as insisting that everyone take medication.

Parent was originally dismissing the complexity of the situation mentally and emotionally by insisting that there's just a simple biochemical thing that needs to be changed, like adding more gasoline or oil to a car engine to make it run longer. The reality is way more complex than that.

Change is really fucking hard and there's no silver bullet solution.

Re: Recovering Emotions After 24 Years on Antidepressants

#143

Earlier quoted context omitted.

> I see medication as the nuclear option. It's important to have it in reserve, since it can work, but you should try everything else first For many people this isn't an option - medication is required to even get them to a stable enough baseline for other treatment options to be effective. Views like this are very unhelpful and help to perpetuate shame, which can prevent people that need help from seeking it because…

> Views like this are very unhelpful and help to perpetuate shame No, my view is a hard-earned perspective that I've gained through personally having the system fail me. I lost a decade of my life to the medication-first mentality and I resent your implication that trying to help others avoid the same outcome is in any way dangerous. I do concede that drugs work for some people, but views like yours that lead to over…

> I resent your implication that trying to help others avoid the same outcome is in any way dangerous.

I resent bad medical advice offered on a public forum. An absolute position in anything is always bad advice when the facts are not known. Parents let their children down, I'm not suddenly going to eschew all parenting because of it.

> What we need is well-rounded advice that allows patients to make informed decisions about their road to recovery. Medication is one possible path, but it's not the only path and it's not without it's downsides.

I think we're actually on the same page, then. Recovery is complicated and we all need to do our best supporting everyone in whatever unique journey leads to their recovery. Medication and therapy (along with family, meditation etc.) are all critical to the process and you don't always get the choice of one without the other. I'm sorry that medication and mental health professionals let you down.

I grew up a little differently than most. Drug-dealing parents, foster care, hoarding, crime & violence, and much worse. I escaped it during the late 90s because I learned to do things other people couldn't (build websites), but I brought my trauma with me as an adult until - as the VP of a start-up that raised over $300MM - lost my shit and then disappeared for 2 years on a "spiritual journey" that included seeing over three dozen mental health professionals.

If it hadn't been for a chance recreational encounter with MDMA the day before my dad died of a sudden heart attack (which precipitated me losing my shit), I would have withdrew into drugs & alcohol instead of seeking the help I needed. I'm especially glad I didn't listen to all the people around me that offered bad advice ("you're fine, look how successful you are") because they couldn't possibly have known the extent of my problems.

Re: Recovering Emotions After 24 Years on Antidepressants

#144
I have had an anxiety problem for a long while now and like the author have recently stopped taking medication for it. I've developed enough techniques from a combination of therapies like mindfulness and CBT and have enough support in place to check this is working that my doctor agrees with this approach. Additionally, I felt the problems caused by the side effects of my medication outweighed the benefits gained by taking it. Finally, I realized that for me exercise simply isn't optional. I have at times in my life been extremely fit and these times have always corresponded to the periods I've handled my anxiety best.

I find the article somewhat troubling in that the author seems to imply that antidepressants are a big pharma conspiracy and are difficult to stop. I personally have had side effects - insomnia, sexual dysfunction, the "fog" the author mentions, although I wouldn't describe it as zombie-like. There are other possible side effects as well, like inducing the liver to release enzymes into the blood stream that imitate fatty liver/liver failure in blood tests, significant weight gain etc. However, I have not had all of these on all tablets - on some, yes, on others, nothing at all. Regarding stopping, the worst case was venlafaxine. I've heard people describe the experience as "brain zaps". It feels a little bit like an electric shock in the brain and is fairly unpleasant (this is with tapering down properly under medical supervision). However, on no antidepressant have I ever felt the need to take the tablet, or to take more of it than the prescribed dose and I have never felt taking a lower dose while stopping to be problematic - it does not resemble fighting addiction at all (I've known people who were addicts and for some of them their addiction killed them, so I have some basis to make this comparison).

Ultimately however, taking antidepressants is a trade off between how bad the side effects are (and I stress that in some cases there were none) and the benefit from the tablet (in some cases, none as well) versus the impact the problem (depression/anxiety/...) is having on your day to day life. In my case and I suspect in the author's case as well, at the time I started taking the tablets the benefits outweighed the side effects and allowed me to be a somewhat functioning member of society. By taking antidepressants I was able access other treatments such as CBT and benefit a little from them, as well as hold down a job. Also, it has to be said that when I first started having problems with my disorder I didn't have anywhere near the same emotional maturity or understanding of myself as I do today. I feel that this understanding has a significant effect on my ability to use things like mindfulness and CBT alone, without any other help - I am benefiting far more from it now. I also wonder if the author would have been so successful with meditation if they had used this and only this technique 24 years ago.

I suspect in many cases finding what works takes time and is a process that can't really be avoided. I'm uncomfortable because the author is implying it can be and moreover that antidepressants should always be avoided. I disagree. I'm glad the author found something that helps and I'd also recommend mindfulness, but I feel that sometimes people need help and antidepressants are one option and that people shouldn't discount them based on articles like this - instead they should have a thorough conversation with a medical professional (if necessary, more than one) about their options.

Re: Recovering Emotions After 24 Years on Antidepressants

#145
post #92

Earlier quoted context omitted.

I am quoting from your link: "The serotonin hypothesis of depression has not been clearly substantiated. Indeed, dogged by unreliable clinical biochemical findings and the difficulty of relating changes in serotonin activity to mood state, the serotonin hypothesis eventually achieved “conspiracy theory” status, whose avowed purpose was to enable industry to market selective serotonin reuptake inhibitors (SSRIs) to a…

Johann Hari covers a lot of the history of antidepressants in "Lost Connections." Per the studies he covers in the book, most of the benefits are placebo effect. The remainder is somewhat of a mystery. Whether you give someone a medication that increases the level of serotonin in their system (i.e. an SSRI), or that decreases the level of serotonin, the effect will the be same. Replace the drugs targeting serotonin w…

Although this is largely correct, there was pushback when that book was published, mostly to do with Hari setting up straw men: https://www.theguardian.com/science/brain-flapping/2018/jan/...

"Now, if your baby dies at 10am, your doctor can diagnose you with a mental illness at 10.01am and start drugging you straight away."

While this is meant as an attack on the modern absence of the “grief exception”, where grief reactions are used to rule out depressive symptoms, it’s at best a staggering exaggeration, at worst an active fabrication to support a narrative. Grief is complex and the medical community is still not agreed on how to deal with it, but the idea that you can be diagnosed with a mental health issue after showing symptoms for one minute is ludicrous. People typically require weeks of symptoms to be officially diagnosed, to suggest otherwise can only damage the perception of medical professionals.

It's a nuanced critique that's worth reading - it's in agreement with a good deal of what Hari writes rather than just being a hatchet job. My take from it (as someone with an MA Honours in experimental psychology and a neuroscience MSc) is that in those parts of the book Hari is criticising outdated practices and opinions in the field that hardly exist any more, if at all.

Having said that, the pharmaceutical industry does have a lot to answer for...

Re: Recovering Emotions After 24 Years on Antidepressants

#146
post #47

This article is absolute bullshit and quite frankly dangerous. It seems to me this woman was emotionally vulnerable and taken in by a snake oil huckster masquerading as a doctor. > Shortly after I started seeing him, my new doctor had me read the book Anatomy of an Epidemic by Robert Whitaker. Robert Whitaker's theses in that book have repeatedly been scientifically disproven. It's anti-science drivel. > The pharmace…

It's not so much that neurotransmitter levels are just lower than they should be - reuptake inhibitors fix that problem very quickly.... A more nuanced modern understanding that we have now is that the increased levels of neurotransmitters in the brain signal the neurons to form more synapses, and this increase in grey matter in key brain regions, over months, is what has been repeatedly shown to improve the conditio…

This sounds a lot like an indirect form of the same mechanism as TMS.

Re: Recovering Emotions After 24 Years on Antidepressants

#147
> I was taking 500 mg of Nefazadone in the evening

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https://en.wikipedia.org/wiki/Nefazodone

Nefazodone is available as 50 mg, 100 mg, 150 mg, 200 mg, and 250 mg tablets for oral ingestion.

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Why would she take such a big dosage of antidepressants? Could she try to reduce the dosage?

Re: Recovering Emotions After 24 Years on Antidepressants

#148
post #87

I'm a bit worried how many people on social media and Internet in general (also here) are fighting some personal war against antidepressants. This is not helping and may cause a lot of suffering to some people. We're in some wacky second generation New Age where everything illogical is the the obvious solution, just for the sake of breaking with the old. There's really many people for whom literally no amount of talk…

As someone who spent a good amount of time on an SSRI, I get where they're coming from. The people who prescribed them to me seemed to think I was fine, and saw no reason I should try to get off them despite personality changes and what I would term "an inability to experience". It was as though I was only able to observe my own life from the outside. The problem with SSRIs isn't that they can't be useful, it's that…

Unfortunately, unless the Dr prescribing them has taken them, it is very hard to appreciate exactly what they are doing to you. There are very subtle effects that are very important to being a happy human that these drugs remove. The data supporting their effectiveness over the absence of them is dubious as well. That isn't to say they don't work, just that over large enough cohorts, the wins and the losses seem to cancel out.

Re: Recovering Emotions After 24 Years on Antidepressants

#149
post #49

Earlier quoted context omitted.

While psilocybin and DMT are being actively researched, I would shy away from recommending people try and use schedule I drugs until they're legalised or at least scheduled differently.

"Schedule 1", as if that means a thing. Bootlicker.

Personal attacks and name-calling will get you banned here. Please don't do this again.

https://news.ycombinator.com/newsguidelines.html

Re: Recovering Emotions After 24 Years on Antidepressants

#150

Earlier quoted context omitted.

What was insane was me being prescribed Paxil as a teenager by a family practice doc with no psychiatric experience or consult, without any therapy, and with only a 20-question questionnaire. What was even crazier was what happened when I quit it cold turkey several months later. The whole experience makes me very skeptical of anyone telling me medication can help me because of how awful my life became.

You really trust your data point of 1.

Please don't be a jerk on HN.
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