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Study: Artificial sweeteners toxic to digestive gut bacteria

cnbc.com

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Re: Study: Artificial sweeteners toxic to digestive gut bacteria

#111

Earlier quoted context omitted.

Perhaps. This is subjective. But I could hardly tell the difference.

The taste difference will never let it pass as candy on its own. It has to be used in foods where other flavors can dominate it, and only let the sweetness through. It's not like it's bad, though. It's just not what sucrose-eaters are accustomed to.

I actually enjoy eating pure erythritol with a tablespoon.

Re: Study: Artificial sweeteners toxic to digestive gut bacteria

#112
post #66

Earlier quoted context omitted.

Paranoid mistrust, cancer fears, and fart-driven explosive diarrhea had already winnowed my list of non-sucrose sweeteners down to just erythritol, pure stevia powder, and very small amounts of xylitol. I'll have to look into lactulose and palatinose.... And it looks like lactulose is out for the diarrhea reason, and isomaltulose--Palatinose is a trademarked name for it--looks practically identical to slow-motion suc…

I've found that stevia sweeteners with inulin (not insulin) seen to be beneficial for my gut bacteria. Actually seems to help with "loose days". Sweetleaf is generally what I use.

Inulin may "help with loose days" much more than you probably think. It may actually help to systematically decrease your appetite and insulin resistance, decrease ghrelin (the "hunger hormone") and increase leptin (the "fullness hormone") if you eat it every day. I can recommend Dr. Raphael Kellman's "The microbiome diet" book for more info, it is easy and exciting to read and has a fair amount references to scientific research in it, it may happen that you will never have to worry about calories again after you read it.

Re: Study: Artificial sweeteners toxic to digestive gut bacteria

#113
I am concerned by the absence of a dose-response until above a threshold concentration for all substances tested. Perhaps osmotic effects, displacement, and chemical competition for receptors, all of which may be in-vitro effects, may explain the curves. Is the threshold relevant to in-vivo concentrations? No idea.

The reason toxicity is expressed as an LD50 is to account for the dose-response of toxins. If toxins behaved as purported in this experiment, we could use a simple concentration number instead: no effect, no effect, no effect, dead.

Also, it looks like all the substances that showed toxic induction did so around the same concentration. Very suspicious for chemically disparate substances with, presumably, different mechanisms of action.

“How can we all have died at the same time? ...(thinks)...The salmon mousse!”

Re: Study: Artificial sweeteners toxic to digestive gut bacteria

#114

The article doesn't say which sweeteners did they study and this is a very bad style. Fortunately it links to an article on EurekAlert which in its turn links to the actual scientific paper (doi.org/10.3390/molecules23102454). It says aspartame, sucralose, saccharine, neotame, advantame and acesulfame potassium-k (ace-k) (BTW at least saccharine and ace-k are already known to be carcinogenic AFAIK) were tested agains…

BTW at least saccharine and ace-k are already known to be carcinogenic AFAIK It would appear that the US FDA and European FSA disagree with you on that subject. Concerning saccharin: In a December 14, 2010 release, the EPA stated that saccharin is no longer considered a potential hazard to human health Wikipedia link: https://en.wikipedia.org/wiki/Saccharin Concerning Acesulfame potassium Critics say acesulfame potas…

Thank you for a lot of interesting information. "Bacterial sensing underlies artificial sweetener-induced growth of gut Lactobacillus" seemed the most interesting to me, funny thing is it's about SUCRAM - a sweetener I've never heard about before now. Where can I possibly buy some? What kind of a chemical substance it even is? Does it have a more scientific name?

Re: Study: Artificial sweeteners toxic to digestive gut bacteria

#115

Earlier quoted context omitted.

There have been studies done where patients were given lots of fruit and it did not cause a laxative effect. https://nutritionfacts.org/2017/02/23/can-you-eat-too-much-f... > Seventeen people were made to eat 20 servings a day of fruit. Despite the extraordinarily high fructose content of this diet, presumably about 200 g/d—eight cans of soda worth, the investigators reported no adverse effects (and possible benefit…

That article says nothing about a laxative effect.

Exactly.

Re: Study: Artificial sweeteners toxic to digestive gut bacteria

#116

Earlier quoted context omitted.

You might be right, I was inferring that the 16 packets was for human levels, but after reading it over again I am not sure that is the case.

A mouse is like 20g. No way are they shoving 16g's of splenda into one.

Well, they wouldn't be using all the filler in any splenda packet, would they? 12mg * 16 mixed into a liquid seems a bit more probable, if still unpleasant.

Re: Study: Artificial sweeteners toxic to digestive gut bacteria

#117
post #78

Seems like everything has artificial sweeteners nowadays. It's a trend that I noticed only in the last couple of years. And not just fizzy drinks like Sprite or Pepsi - which have sugar and sweetener! - but breakfast cereals, yoghurts, ketchup-like sauces... all have "no added sugar" on the package, you dig a bit deeper and they are full of sweeteners. Chewing gum and other "healthy sweet" products like that have use…

> breakfast cereals, yoghurts, ketchup-like sauces If you're trying to avoid both sugar and sweeteners, those aren't the kinds of foods you're going to be eating... Unless you're referring to plain oats and plain yoghurt, which surely must be available unsweetened and unadulterated.

I’m always surprised at what people eat when they’re deliberately trying to be healthy. Things like Nutrigrain bars and GoGurt. Really makes me realize what a failure our labeling laws our when both can be sold as anything other than dessert.

Re: Study: Artificial sweeteners toxic to digestive gut bacteria

#118

Earlier quoted context omitted.

That article says nothing about a laxative effect.

Exactly.

You failed to provide evidence that fruit exhibits no laxative effect. That study didn't report a laxative effect because it wasn't testing for a laxative effect.

Re: Study: Artificial sweeteners toxic to digestive gut bacteria

#119
I was big on artificial sweeteners (I refuse to eat any sugar), mainly erythritol and monkfruit, but some science(1) says that just their taste profile can trick your body into thinking it's consuming a real sugar with the associated glucose/insulin response and this could be one reason as to why non-nutritive sweeteners can throw your blood and insulin response profiles out of whack, which may be a reason as to why individuals who consume artificial sweeteners suffer the same maladies as those who consume high levels of sugar.

If the science on this issue becomes conclusively affirmative, then it's sort of the nail in the coffin for artificial sweeteners, because it doesn't matter what the compositional makeup of the sweetener is, it's our own bodies own responses to the taste/smell that are giving us the ill effects.

I would definitely like to be dissuaded as to believing this is not the case, though, as it's caused my to ignore my sweet tooth for far too long! :)

For those who are interested in and/or consume artificial sweeteners, I think this link is definitely worth a read:

[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661066/

Re: Study: Artificial sweeteners toxic to digestive gut bacteria

#120

Earlier quoted context omitted.

BTW at least saccharine and ace-k are already known to be carcinogenic AFAIK It would appear that the US FDA and European FSA disagree with you on that subject. Concerning saccharin: In a December 14, 2010 release, the EPA stated that saccharin is no longer considered a potential hazard to human health Wikipedia link: https://en.wikipedia.org/wiki/Saccharin Concerning Acesulfame potassium Critics say acesulfame potas…

Thank you for a lot of interesting information. "Bacterial sensing underlies artificial sweetener-induced growth of gut Lactobacillus" seemed the most interesting to me, funny thing is it's about SUCRAM - a sweetener I've never heard about before now. Where can I possibly buy some? What kind of a chemical substance it even is? Does it have a more scientific name?

Doubt if you'd want to ingest it. It's a saccharin-based animal feed enhancer.

URL: http://alliednutrition.com/wp-content/uploads/2015/09/AN-Suc...

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