A bone-marrow transplant treated a patient’s leukemia – and his schizophrenia • Hacker News Board

Re: A bone-marrow transplant treated a patient’s leukemia – and his schizophrenia

#11

Post by solveit » Mon, Oct 01, 2018, 12:27 AM UTC

WalterSear wrote: post #9

Jugglerofworlds wrote: post #5

I've long suspected that my depression & OCD were caused by some immune response. It all started very suddenly when I had a very bad illness. Unfortunately I have yet to find a doctor that believes me and is willing to do anything other than giving me the standard medications.

I treat my treatment resistant depression by inducing 101+ fever for half an hour each day. I started when I had to stop an allergy to the EMSAM patch. There are also medications that you might not have heard of. If you want, I can write more when I'm not on mobile.

How do you induce a fever?

Re: A bone-marrow transplant treated a patient’s leukemia – and his schizophrenia

#12

Post by CynicalDio » Mon, Oct 01, 2018, 1:03 AM UTC

WalterSear wrote: post #9

Jugglerofworlds wrote: post #5

I've long suspected that my depression & OCD were caused by some immune response. It all started very suddenly when I had a very bad illness. Unfortunately I have yet to find a doctor that believes me and is willing to do anything other than giving me the standard medications.

I treat my treatment resistant depression by inducing 101+ fever for half an hour each day. I started when I had to stop an allergy to the EMSAM patch. There are also medications that you might not have heard of. If you want, I can write more when I'm not on mobile.

What are these alternative meds?

Re: A bone-marrow transplant treated a patient’s leukemia – and his schizophrenia

#13

Post by torpfactory » Mon, Oct 01, 2018, 1:39 AM UTC

Just a friendly reminder not to get medical advice from anonymous strangers on the internet. There are some pretty serious interventions described in the comments below as things you could try at home.

Re: A bone-marrow transplant treated a patient’s leukemia – and his schizophrenia

#14

Post by olliej » Mon, Oct 01, 2018, 1:52 AM UTC

torpfactory wrote: post #13

Just a friendly reminder not to get medical advice from anonymous strangers on the internet. There are some pretty serious interventions described in the comments below as things you could try at home.

Also don’t use webmd :)

See an actual clinician

Re: A bone-marrow transplant treated a patient’s leukemia – and his schizophrenia

#15

Post by Arete31415 » Mon, Oct 01, 2018, 2:08 AM UTC

Jugglerofworlds wrote: post #5

I've long suspected that my depression & OCD were caused by some immune response. It all started very suddenly when I had a very bad illness. Unfortunately I have yet to find a doctor that believes me and is willing to do anything other than giving me the standard medications.

Another one person data point:

I've had OCD since childhood, and even when I was a kid I noticed that sometimes my symptoms would flare up for a few days, right before I came down with the flu.

As an adult, I contracted Lyme Disease, and one lingering symptom was that my OCD got a lot worse. After 1 month of IV antibiotics (rocephin), my OCD went from a "10" down to maybe a 7 in severity.

Re: A bone-marrow transplant treated a patient’s leukemia – and his schizophrenia

#16

Post by baccheion » Mon, Oct 01, 2018, 2:29 AM UTC

Jugglerofworlds wrote: post #5

I've long suspected that my depression & OCD were caused by some immune response. It all started very suddenly when I had a very bad illness. Unfortunately I have yet to find a doctor that believes me and is willing to do anything other than giving me the standard medications.

There is an autoimmune theory of schizophrenia. Excess histamine can also cause OCD-like symptoms.

Look into megadose vitamin D3 (+ K2 MK-4 + magnesium). Memantine + selank. Lowering inflammation.

Re: A bone-marrow transplant treated a patient’s leukemia – and his schizophrenia

#17

Post by raincom » Mon, Oct 01, 2018, 2:41 AM UTC

Jugglerofworlds wrote: post #5

I've long suspected that my depression & OCD were caused by some immune response. It all started very suddenly when I had a very bad illness. Unfortunately I have yet to find a doctor that believes me and is willing to do anything other than giving me the standard medications.

You need to find a doctor like late Oliver Sacks and Ramachandran. Basically, a research oriented doctor.

Re: A bone-marrow transplant treated a patient’s leukemia – and his schizophrenia

#18

Post by Jugglerofworlds » Mon, Oct 01, 2018, 3:12 AM UTC

loceng wrote: post #10

Jugglerofworlds wrote: post #5

I've long suspected that my depression & OCD were caused by some immune response. It all started very suddenly when I had a very bad illness. Unfortunately I have yet to find a doctor that believes me and is willing to do anything other than giving me the standard medications.

Have a way to contact you directly?

Sure, you can email me at jugglerofworlds123@gmail.com

Re: A bone-marrow transplant treated a patient’s leukemia – and his schizophrenia

#19

Post by Jugglerofworlds » Mon, Oct 01, 2018, 3:16 AM UTC

baccheion wrote: post #16

Jugglerofworlds wrote: post #5

I've long suspected that my depression & OCD were caused by some immune response. It all started very suddenly when I had a very bad illness. Unfortunately I have yet to find a doctor that believes me and is willing to do anything other than giving me the standard medications.

There is an autoimmune theory of schizophrenia. Excess histamine can also cause OCD-like symptoms. Look into megadose vitamin D3 (+ K2 MK-4 + magnesium). Memantine + selank. Lowering inflammation.

I tried prescription memantine, both the generic and XR formulations. The brain fog startup side effect never went away for me, so I had to quit. I've never found a supplement that has actually done anything.

Re: A bone-marrow transplant treated a patient’s leukemia – and his schizophrenia

#20

Post by Jugglerofworlds » Mon, Oct 01, 2018, 3:27 AM UTC

Nasrudith wrote: post #8

Jugglerofworlds wrote: post #5

I've long suspected that my depression & OCD were caused by some immune response. It all started very suddenly when I had a very bad illness. Unfortunately I have yet to find a doctor that believes me and is willing to do anything other than giving me the standard medications.

Technically mental trauma could have done so as well - which you probably heard dozens of times. Even if a doctor believed you I am not sure what they could do that wouldn't be extremely ill advised. Immunosuppressants would be tough to justify even if it was a certain cure instead of a highly tentative one. I know it is a frustrating situation to be in. Like I know that oral general anesthesia would help me for bloo…

Yes, there are likely multiple factors here, both physical and learned behaviors. I've had some access to cutting edge treatments since I live in Boston, which is probably the #1 place in the world for psychiatry research. Over the years I've cobbled together a regimen that sort of works, but it's basically a band-aid solution and I can tell that it's not 100% effective.

Nowadays I feel normal ish about 15% of the time, meh about 50%, and somewhat depressed 35%. I've tried multiple medications from pretty much every category of medications, including many off-label treatments.