Pivotal CRISPR patent battle won by Broad Institute
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Re: Pivotal CRISPR patent battle won by Broad Institute
#2What would a world with commercialized CRISPR technology look like? Will they just sit in the back and collect fees like the MP3 patent owners? Or will they spin-off and became the Google of DNA editing?
Re: Pivotal CRISPR patent battle won by Broad Institute
#3What would a world with commercialized CRISPR technology look like? Will they just sit in the back and collect fees like the MP3 patent owners? Or will they spin-off and became the Google of DNA editing?
we’re about to find out. Editas Pharmaceuticals is, i believe, the sole commercial licensee by the Broad for CRISPR/Cas-9, and they are scheduled to begin human trials for a rare form of blindness in October.
Re: Pivotal CRISPR patent battle won by Broad Institute
#4What would a world with commercialized CRISPR technology look like? Will they just sit in the back and collect fees like the MP3 patent owners? Or will they spin-off and became the Google of DNA editing?
It's good to keep in mind that CRISPR is but one technique to do gene splicing, it's not the concept itself. Different ways will be discovered now that it's proven to be viable.
Re: Pivotal CRISPR patent battle won by Broad Institute
#5I'm wondering, is there a hacker news for biohacking related stuff?
I have the feeling that there is a lot of progress being made in gene therapy technology these days. Having a friend who's life would be enhanced by gene therapy, I'm highly interested!
Re: Pivotal CRISPR patent battle won by Broad Institute
#6I'm wondering, is there a hacker news for biohacking related stuff? I have the feeling that there is a lot of progress being made in gene therapy technology these days. Having a friend who's life would be enhanced by gene therapy, I'm highly interested!
Closest I know of is Fierce Biotech https://www.fiercebiotech.com/
Re: Pivotal CRISPR patent battle won by Broad Institute
#7I'm wondering, is there a hacker news for biohacking related stuff? I have the feeling that there is a lot of progress being made in gene therapy technology these days. Having a friend who's life would be enhanced by gene therapy, I'm highly interested!
Closest I know of is Fierce Biotech https://www.fiercebiotech.com/
thanks a lot!
Re: Pivotal CRISPR patent battle won by Broad Institute
#8Sucks for UC, but I'm sure if the situations had been reversed they would've fought as hard for the patent as the Broad has.
Re: Pivotal CRISPR patent battle won by Broad Institute
#9What would a world with commercialized CRISPR technology look like? Will they just sit in the back and collect fees like the MP3 patent owners? Or will they spin-off and became the Google of DNA editing?
It's good to keep in mind that CRISPR is but one technique to do gene splicing, it's not the concept itself. Different ways will be discovered now that it's proven to be viable.
I think we've known it would be useful for a long time, we have had general editing capabilities for a long time, they have just been less precise/customizable. So I don't think a new one will be easily found.
Re: Pivotal CRISPR patent battle won by Broad Institute
#10I'm wondering, is there a hacker news for biohacking related stuff? I have the feeling that there is a lot of progress being made in gene therapy technology these days. Having a friend who's life would be enhanced by gene therapy, I'm highly interested!
Gene therapy has had some recent successes [0], but it is worth noting that many of the ongoing and recent clinical gene therapy trials don’t necessarily involve genome editing: go to clinicaltrials.gov, search ‘gene therapy’ and get 3741 results. Search ‘CRISPR’ or ‘TALEN’ and get ~21 results.
Edit: I should say that most of the gene therapy clinical trials don’t involve genome editing yet. Though it seems to me that, at least for some diseases, viral vectors that deliver DNA to cells without integrating DNA into the host cell genome (where the dna instead persists inside the cells episomally, and is maybe lost from the cells after some number of divisions) will have advantages over integrating vectors/genome editing-based approaches. That way, you don’t have to worry about the off-target effects of genome editing, and you have a treatment that doesn’t result in permanent changes to the genome.