http://news.bbc.co.uk/2/hi/health/8492918.stm
Tldr:- Didn’t find any specific gene linkage. Less stress, low cholesterol and the other standard healthy metrics seems to make a difference.
Having Alzheimer’s at 38 (2015)
31–40 of 145 posts
Re: Having Alzheimer’s at 38 (2015)
#32Reading this will rightfully scare the bejeezus out of us. The question is, what can we do? Alzheimer is sometimes referred to as diabetes type 3. Cutting out sugar and eating a low carb diet is a good precaution. It likely wouldn't have helped Jo, but it might save quite a few of us from this scary outcome.
You really need to cite such a claim. Thanks.
The term 'type 3 diabetes' has been around for at least a decade and has been written about in some of the most mainstream publications around. It's hardly a term that needs to be cited. If you were to use Google, you could find well cited articles like this.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769828/
Or, here's some more current research being done at the Mayo clinic.
https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-mi...
Re: Having Alzheimer’s at 38 (2015)
#33There is a link between Alzheimer and fungal infections in the brain and a compromised blood/brain barrier.
Re: Having Alzheimer’s at 38 (2015)
#34Diseases which affect your brain are quite bizarre in terms of quantifying the effects. I have some lesion damage from multiple sclerosis, but there's very little information available on what effects, if any I'd be able to identify. It's quite a bizarre experience to have physical damage that manifests in such a way that the entire outcome is subjective (was not putting clothes in the dryer an effect of Alzheimers?…
The Brain has a fair amount of redundancy and adaptability, but you use that to deal wide a huge range of issues. So, up to a point you simply get worse side effects from aging, concussions, drug use etc. Making a list of symptoms hard to generalize.
Yep. For MS in particular you can get very specific damage that can't be mitigated by other parts of the brain, but in general the amount of malleability hides a lot of impact until later.
Re: Having Alzheimer’s at 38 (2015)
#35My Mother started experiencing dementia at 57 and it has been difficult to see such a brilliant, adventurous worldly woman change. She is still the person whom she was but now she is a creature of habit and does the same thing and the same time everyday of the week. Leaving her neighborhood and visiting new places including restaurants and parks makes her uncomfortable. She used to love traveling to places like Kenya, Portugal and Indonesia but now she just wants to stay local. She was quite a sculptor too but gave that up to raise five children and now that all of us are out of the house she doesn’t have the capacity to peruse her old passion any longer. Moreover our conversations have progressively become shorter and shorter over the years and lost a lot of depth. As her son it’s very difficult to deal with. Moreover I’m in constant fear I will be afflicted too as my grandmother had Alzheimer’s as well. Maybe AI or some other tool will be utilized to develop medications and treatments to halt and reverse the disease in the future, fingers crossed.
Re: Having Alzheimer’s at 38 (2015)
#36Earlier quoted context omitted.
> Alzheimer is sometimes referred to as diabetes type 3. Just because it is referred to that way doesn't mean that it is actually the case. The hypothesis that AD=Diabetes has been around for at least ten years [1]. If it were true, I would have expected to see some results by now about how diabetes interventions can slow the advance of AD, if not prevent and/or reverse it entirely. AFAICT there have been no such res…
We're only now just waking up to the reality that type-2 diabetes can be reversed w/ carbohydrate restriction, even though the data to support that has been around for decades. I don't think a decade is an unusual latency for the medical institution to lay idle on.
>We're only now just waking up to the reality that type-2 diabetes can be reversed w/ carbohydrate restriction
I don’t think this is a new/recent revelation at all (and in fairness, I cut the next part of your quote that acknowledges decades old research).
And while not all cases of type 2 can be reversed (most can) but maybe more importantly 100% of cases can be prevented through diet/exercise.
Re: Having Alzheimer’s at 38 (2015)
#37Earlier quoted context omitted.
You really need to cite such a claim. Thanks.
The term 'type 3 diabetes' has been around for at least a decade and has been written about in some of the most mainstream publications around. It's hardly a term that needs to be cited. If you were to use Google, you could find well cited articles like this. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769828/ Or, here's some more current research being done at the Mayo clinic. https://newsnetwork.mayoclinic.org/di…
I've now googled it and learned it's a controversial term not embraced by the medical community. Thanks.
Re: Having Alzheimer’s at 38 (2015)
#38My wife's family has a different disease running through it, though one with very similar outcomes. Huntington's.
It's genetic and dominant (so a parent having it means 50/50 for the children). Average age of onset is 38. Symptoms are a mixture of Alzheimer's and Parkinson's (both dementia and motor control issues).
Her uncle was diagnosed at 38, her mother at 50. I wasn't around for the first one, but have been there for most of the latter case (her mother is now 60).
Watching someone you love deteriorate before your eyes and become a different person week by week is one of the most harrowing experiences one can go through.
"You pick up the phone, you talk to your mom, you don’t have to say anything. It’s a mom". My wife had to go through discovering motherhood without that and she still can't adjust to the fact that her mother is not the same person anymore, it's a constant heartbreak.
I'm just glad there's a simple test for this and that both my wife and her one brother tested negative. So I'll never have to go through what Robin did but that possibly was something I had to contemplate for a while and just the thought of it (and those 2 months waiting for the test results) almost broke me
Re: Having Alzheimer’s at 38 (2015)
#39There's a lot of scientific evidence that medical marijuana can remove beta-amyloid build up in the brain. There is also evidence that unknown spirochete diseases can cause Alheimer like symptoms. There is also cause for concern that bio-pesticides that are GMO based are can infect the brain and cause symptoms like this as well. I would definitely never give up if this happened to me. Antibiotics, antiparasite, diet…
> There's a lot of scientific evidence
I would like to see this. Do you have a link to a peer reviewed study?
Re: Having Alzheimer’s at 38 (2015)
#40I have tears. I fear this more than I realized before.
I think I just need to say a few things. So they exist somewhere, because of that fear, anger and sadness brought to me by this story.
I remember the day I woke up, and by that, I mean the difference between being that kid, experiencing, and who I am today.
It happened for me in 2nd grade. End of year, and I realized I could no longer choose to read, it just happened. And I was angry, and excited at the same time.
Was never the same.
That year was the beginning of me, and while I remember a lot from my very early years, those memories aren't like the ones I have later on.
I would fear going to sleep. Would I be the same again, or someone new, or would I forget those realizations I had at the end of that second school year?
The idea of "me" being a fragile state, a pattern that tends to endure, provoked a sense of guardianship. I am in charge of me, nobody else.
That caused me considerable grief growing up. Others, wanting to help, were dofficult to let in. How can I tell that, the human teasing out of who we are becoming, from manipulation rooted in self-serving, toxic ends, not mine, me?
Took years to resolve, and with it came a joy in knowing me, seeing me happen, grow. And others. People of all kinds. It is fun to meet them, see who they are.
That should explain the fear. I am very aware of me, that identity I felt congeal into a thing made aware, to grasp, and guard lest it fase, shift, be lost.
To have it just degrade, fade away despite ehat I know must be a painful struggle...
We need to do the work on this thing. It could be any of us, and ours facing this quiet horror.
Jo is a lucky person. He has someone who knows his story, who can take him back, connect.