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Researchers Find Herpes Viruses in Brains Marked by Alzheimer's Disease

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Re: Researchers Find Herpes Viruses in Brains Marked by Alzheimer's Disease

#41
post #6

Earlier quoted context omitted.

"Reader Mode" is built into Firefox. (Dunno about chrome, I don't use that) There is also https://outline.com

You have no idea how helpful this is to me right now. I am in Chile on the most abominably slow pre-paid cell phone connection. I'm reading this from the mountains as we speak Thank you so much

Put the phone down! :-)

Re: Researchers Find Herpes Viruses in Brains Marked by Alzheimer's Disease

#42
The study referenced in the article says they found HHV-6 in normal brains but there was "increased HHV-6A and HHV-7 in brains of subjects with Alzheimer’s disease" [1]. So I would say that is surprising and worth noting.

[1] https://www.cell.com/neuron/fulltext/S0896-6273(18)30421-5

Re: Researchers Find Herpes Viruses in Brains Marked by Alzheimer's Disease

#43

As someone who gets cold sores this worries me. I know when I am super stressed because a cold sore will begin to appear on my lip. It's always there but stress allows it to replicate, all parts of my immune system are not able to cope during stressful events. I hope this doesn't mean I'm at risk for Alzheimer's disease. At least it's now known when people sleep it clears out beta-amyloid proteins in their brains. No…

Note that these results describe the presence of HHV-6 and HHV-7, which cause roseola. Herpes simplex is HSV-1 and HSV-2, which cause cold sores and genital herpes, respectively.

Ah thanks, good to know.

Re: Researchers Find Herpes Viruses in Brains Marked by Alzheimer's Disease

#44
post #40

Earlier quoted context omitted.

I don't know your situation, but if you don't already, you should get an RX for Valtrex or some other anti-viral. You can usually take it _before_ the cold sore appears if you can tell it's about to (swelling, stress, etc...) – and it can and often entirely suppresses the external appearance for most people.

Dude, that seems insane to me. Maybe you haven’t ever dived into the possible side effects of anti virals. But maybe you should? The risk/reward ratio of such a drug for cold sores is extremely poor.

Are we thinking of the same drug? Because Valtrex is pretty safe as long as your kidneys are normal and you drink enough water every day. I take 500 mg daily to prevent 5 to 10 (at least!) cold sores per year. My quality of life is so much higher with this drug (imagine not being able to be intimate on like half of all your dates...) For people like me who get cold sores at the drop of a hat (or shaving or even a sharp cold breeze), it’s a fine risk, and I’d even be willing to risk more.

Re: Researchers Find Herpes Viruses in Brains Marked by Alzheimer's Disease

#45
Someone noted (vedtopkar) these are "HHV-6 and HHV-7, which cause roseola". Note that it's an incredibly common infection in babies.

There's also another study investigating association between HHV-6 and measles virus serology and brain antibody in autism:

https://www.ncbi.nlm.nih.gov/pubmed/9756729

Reading these studies makes me think an ineffective blood-brain barrier or a brain-specific defence might trigger common viruses to present a wider family of brain-related diseases.

We also know there is literature on encephalitis caused by both HHV-6 and measles. I'm speculating that even in a micro, benign form, this condition is enough the shake brain structure.

We should probably investigate a more complex but more generic model of brain diseases.

Re: Researchers Find Herpes Viruses in Brains Marked by Alzheimer's Disease

#46

Earlier quoted context omitted.

You have no idea how helpful this is to me right now. I am in Chile on the most abominably slow pre-paid cell phone connection. I'm reading this from the mountains as we speak Thank you so much

Put the phone down! :-)

But I need to take photos like this! [1]

We have service here, believe it or not. There's even wifi at 9,000ft in elevation. We're at 13,000 feet right now

https://imgur.com/ZWOC3Bd

Re: Researchers Find Herpes Viruses in Brains Marked by Alzheimer's Disease

#47
post #34

Earlier quoted context omitted.

We've asked you a number of times to please make your comments thoughtful and informative. If you won't, we'll ban the account. https://news.ycombinator.com/newsguidelines.html

Respectfully, which rule is at issue here?

This site is for substantive, intellectually interesting discussion. The guidelines aren't rules (or else that's what they'd be called), they're there to help guide us in that direction. When commenters repeatedly post unsubstantive comments from which we don't stand to learn anything, that's not using the site as intended. If there isn't any insight in your comment, don't post it.

Re: Researchers Find Herpes Viruses in Brains Marked by Alzheimer's Disease

#48

As someone who gets cold sores this worries me. I know when I am super stressed because a cold sore will begin to appear on my lip. It's always there but stress allows it to replicate, all parts of my immune system are not able to cope during stressful events. I hope this doesn't mean I'm at risk for Alzheimer's disease. At least it's now known when people sleep it clears out beta-amyloid proteins in their brains. No…

I don't know your situation, but if you don't already, you should get an RX for Valtrex or some other anti-viral. You can usually take it _before_ the cold sore appears if you can tell it's about to (swelling, stress, etc...) – and it can and often entirely suppresses the external appearance for most people.

Thats's interesting but I'm referring to a cold sore not the genital or other types.

As annoying as it is I can live with it I was just worried it was the type that raised the risk of Alzheimer's disease.

Re: Researchers Find Herpes Viruses in Brains Marked by Alzheimer's Disease

#50

Earlier quoted context omitted.

I don't know your situation, but if you don't already, you should get an RX for Valtrex or some other anti-viral. You can usually take it _before_ the cold sore appears if you can tell it's about to (swelling, stress, etc...) – and it can and often entirely suppresses the external appearance for most people.

Thats's interesting but I'm referring to a cold sore not the genital or other types. As annoying as it is I can live with it I was just worried it was the type that raised the risk of Alzheimer's disease.

Valacyclovir treats a broad range of viruses: "shingles, cold sores, and genital herpes. It can also treat chickenpox..."
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