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First physiological test for autism proves high accuracy in second trial

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Re: First physiological test for autism proves high accuracy in second trial

#51

Post by [deleted] »

hhh wrote: post #38
TheSpiceIsLife wrote: post #35

Earlier quoted context omitted.

> spectrum is of infinite width and infinite height If this were true, everyone is diagnosable.

It was more for the aesthetic of the sentence, but if you have a spectrum including 'normalcy' that is infinite width and infinite height, with x being ability (a combined measurement of communication ability, sensitivities, etc) and y being level of function, it is possible to include 'normalcy' as it is defined at the farthest top right corner. This could even have more dimensions to it, represented as 0-1 on each.…

[deleted]

Re: First physiological test for autism proves high accuracy in second trial

#52

Post by smt88 »

magic_beans wrote: post #36
smt88 wrote: post #20

Earlier quoted context omitted.

I don't know, but there's preliminary evidence that autism can be reversed by dosing children with oxytocin and by using TMS on adults. Because those approaches are considered to be fairly low-risk, I suspect research will continue in those directions until they hit a wall of some kind.

What does it even mean to “reverse autism”?

Most famous example: https://well.blogs.nytimes.com/2016/03/18/an-experimental-au...

It allows people to read faces and emotional context in a way they couldn't before. Some people find that their decision-making becomes less logical and more emotional. For others, nothing changes.

If you search "tms autism" there are other firsthand accounts that you might find interesting.

Re: First physiological test for autism proves high accuracy in second trial

#53

Post by hosh »

smt88 wrote: post #20
amelius wrote: post #17

Does this also work in reverse? I.e. take supplements/drugs until the test is negative, and then be (temporarily) autism-free?

I don't know, but there's preliminary evidence that autism can be reversed by dosing children with oxytocin and by using TMS on adults. Because those approaches are considered to be fairly low-risk, I suspect research will continue in those directions until they hit a wall of some kind.

I have not heard of using oxytocin for children on the specturm. Are there articles, resources, or papers that talk about this?

Re: First physiological test for autism proves high accuracy in second trial

#54

Post by hosh »

bcatanzaro wrote: post #24

If this test becomes widespread, I'd love to take it. I bet many of us in the tech industry have some sort of autism markers. It is a spectrum, after all.

There is also this recently published work: http://stm.sciencemag.org/content/9/393/eaag2882

This one uses machine learning and brain scans to predict the diagnoses for someone as young as 6 months old. It also predicts the severity.

What's also interesting is how it differentiate between people who are at-risk, but without a diagnoses, and those who are at-risk, and have a diagnoses.

I also wonder if there are more to be studied with the Broad Autism Phenotype (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746421/)

Re: First physiological test for autism proves high accuracy in second trial

#56

Post by throwawaymath »

gowld wrote: post #34
throwawaymath wrote: post #29

Earlier quoted context omitted.

No, "disorder" is explicitly clinical. The words "retarded", "dumb", and "stupid" are pejorative. Calling autism a disorder is an accurate paychiatric description, not a value judgement designed to insult a person's identity. An insult can be targeted at a person's autism, but not simply by describing it according to clinical terminology. I sympathize with people who don't believe autism should be considered a disord…

"retarded" and "dumb" are also clinical terms. They only stopped being clinical terms because people attached connotations. https://en.wiktionary.org/wiki/euphemism_treadmill

Alright, if you'd like me to excessively specify my point: "retarded" and "dumb" are adjectives not used in the DSM 5, which means they are not modern clinical terms. They have also been abolished completely. "Disorder" is still in common use, not only for autism but across the DSM as a common term meaning "atypical and diagnosable." So yes, "disorder" is an appropriate term at the moment. Whether it will continue to be in the future is irrelevant for present conversation.

For what it's worth, if you're arguing that "disorder" should not be used on the basis of precedents like "dumb" and "retarded", the page you cited is an exceptionally poor reference. The quotes appear to be mocking this phenomenon.

Re: First physiological test for autism proves high accuracy in second trial

#57

Post by samatman »

hhh wrote: post #38
TheSpiceIsLife wrote: post #35

Earlier quoted context omitted.

> spectrum is of infinite width and infinite height If this were true, everyone is diagnosable.

It was more for the aesthetic of the sentence, but if you have a spectrum including 'normalcy' that is infinite width and infinite height, with x being ability (a combined measurement of communication ability, sensitivities, etc) and y being level of function, it is possible to include 'normalcy' as it is defined at the farthest top right corner. This could even have more dimensions to it, represented as 0-1 on each.…

This is wrong twice I'm afraid.

First: a graph with two infinite dimensions doesn't have a top right point, it has a top right extent.

Second: when graphing, you don't get to pick what the normal is. That's a property of the graph. It is not the (impossible) property you've described.

Re: First physiological test for autism proves high accuracy in second trial

#58

Post by amelius »

smt88 wrote: post #52
magic_beans wrote: post #36

Earlier quoted context omitted.

What does it even mean to “reverse autism”?

Most famous example: https://well.blogs.nytimes.com/2016/03/18/an-experimental-au... It allows people to read faces and emotional context in a way they couldn't before. Some people find that their decision-making becomes less logical and more emotional. For others, nothing changes. If you search "tms autism" there are other firsthand accounts that you might find interesting.

Have there been any scientific experiments already to validate this method?

Re: First physiological test for autism proves high accuracy in second trial

#59

Post by smt88 »

amelius wrote: post #58
smt88 wrote: post #52

Earlier quoted context omitted.

Most famous example: https://well.blogs.nytimes.com/2016/03/18/an-experimental-au... It allows people to read faces and emotional context in a way they couldn't before. Some people find that their decision-making becomes less logical and more emotional. For others, nothing changes. If you search "tms autism" there are other firsthand accounts that you might find interesting.

Have there been any scientific experiments already to validate this method?

As of 2 years ago, there were more than a dozen clinical trials. Evidence is preliminary -- populations are small, and measuring how autistic someone is is not easy.

https://www.autismspeaks.org/blog/2016/03/25/transcranial-ma...

Re: First physiological test for autism proves high accuracy in second trial

#60

Post by smt88 »

hosh wrote: post #53
smt88 wrote: post #20

Earlier quoted context omitted.

I don't know, but there's preliminary evidence that autism can be reversed by dosing children with oxytocin and by using TMS on adults. Because those approaches are considered to be fairly low-risk, I suspect research will continue in those directions until they hit a wall of some kind.

I have not heard of using oxytocin for children on the specturm. Are there articles, resources, or papers that talk about this?

I'm on my phone, so it's hard to search and link to articles. Here's the result of a quick search:

https://www.spectrumnews.org/news/oxytocin-spray-boosts-soci...

Hopefully that serves as a jumping off point.

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