People were skeptical of Theranos' claims before the WSJ expose from Oct 15, 2015. Here are some examples that predate that article: http://www.businessinsider.com/scientist-skeptical-thranos-b... http://www.businessinsider.com/science-of-elizabeth-holmes-t... This discussion from 2013 talks about Theranos doing full blood draws which they wouldn't need to do if their technology worked: https://forums.studentdoctor.n…
I brought this up in a comment downstream, but it was a Dec. 17, 2014, blog post by the now defunct Pathology Blawg that arguably led to the downfall of Theranos. The Blawg author was contacted by someone feuding with Holmes at the time. The Blawg author eventually contacted the WSJ reporter in secret: http://archive.is/BGtRJ One of the compelling things the Blawg author did was note this passage in the New Yorker st…
Ask HN: Elizabeth Holmes has 200 patents – if tech didn't work, why not noticed?
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Re: Ask HN: Elizabeth Holmes has 200 patents – if tech didn't work, why not noticed?
#72Their philosophy can best be summarized as, "Rubber-stamp 'em all and let the courts sort 'em out." We all get to pay for that.
Re: Ask HN: Elizabeth Holmes has 200 patents – if tech didn't work, why not noticed?
#73Earlier quoted context omitted.
The truth is that in the alternative timeline where Theranos had a male founder they would never gotten their initial founding. Holmes and Theranos rode the perfect wave built by the media being thirsty for a young, smart (blonde) female. It's so obvious when you look at it in hindsight. Hilariously, even after the total collapse this topic is often taboo. I can't help but feel for sorry for the young women out there…
Theranos's first funding was in 2004, it had already raised $90M at $1B valuation in 2010, and started filling its board with defense bigwigs in 2011. What media wave had happened at that point? From what I've seen, serious media coverage appeared in 2013, when they left "stealth mode" with the promise of the droplet testing, almost a decade after the initial investment.
Re: Ask HN: Elizabeth Holmes has 200 patents – if tech didn't work, why not noticed?
#74Earlier quoted context omitted.
There are thousands of patents for perpetual motion machines. An invention must be novel, useful and non-obvious to be patentable, but it doesn't actually have to work. https://patents.google.com/?q="perpetual+motion"
I thought perpetual motion machines claims were automatically denied. I know they were back in the 1970s when my dad worked at the patent office.
Re: Ask HN: Elizabeth Holmes has 200 patents – if tech didn't work, why not noticed?
#75Earlier quoted context omitted.
Holmes figured out a pathway to violate the trust of old man wisdom. Sounds like she just fished the right old men. One of those that that’s incredibly mature in one aspect of life and threw all her effort in that direction naively ignoring the rest of of what “trust” actually facilitates. Poo poo for the men who were fished... don’t s*!t where you eat.
Many of the board members of Theranos were retired military officials, which seems especially interesting in the context of how Theranos was originally planning on selling the technology that we now know to be non-working to the military. I recall that the sale was originally blocked by low-level military regulators. Holmes may not have scammed as many people as we thought - the window is open on the idea that some o…
Re: Ask HN: Elizabeth Holmes has 200 patents – if tech didn't work, why not noticed?
#76You’ve got to consider who has incentives to do the research. This basically breaks down into a few categories: 1) entrenched competitors that want to protect market share. 2) hedge funds that start OTC trading and are shorting. 3) insiders that want to vaporize the company as part of a bizarre money laundering scheme. (Most likely, although very bizarre, option imo.) 4) the rare journalist that does investigative re…
Unless, of course, they are sniffing around looking for funding. Consider for example the current NIH/alcohol kerfuffle.
Re: Ask HN: Elizabeth Holmes has 200 patents – if tech didn't work, why not noticed?
#77Earlier quoted context omitted.
I brought this up in a comment downstream, but it was a Dec. 17, 2014, blog post by the now defunct Pathology Blawg that arguably led to the downfall of Theranos. The Blawg author was contacted by someone feuding with Holmes at the time. The Blawg author eventually contacted the WSJ reporter in secret: http://archive.is/BGtRJ One of the compelling things the Blawg author did was note this passage in the New Yorker st…
Ouch, the quote from Elizabeth Holmes on how the machine worked: > "A chemistry is performed so that a chemical reaction occurs and generates a signal from the chemical interaction with the sample, which is translated into a result, which is then reviewed by certified laboratory personnel."
Re: Ask HN: Elizabeth Holmes has 200 patents – if tech didn't work, why not noticed?
#78The patents don't really tell you whether the Theranos technology actually works. They cover small parts of the overall system - fluid handling, centrifuge configurations, software processes and so on. It's quite common for companies to use a mix of patents and trade secrets to protect their technology. Filing for patent protection is a tradeoff - you gain the exclusive right to use that invention for 20 years, but t…
Holmes figured out a pathway to violate the trust of old man wisdom. Sounds like she just fished the right old men. One of those that that’s incredibly mature in one aspect of life and threw all her effort in that direction naively ignoring the rest of of what “trust” actually facilitates. Poo poo for the men who were fished... don’t s*!t where you eat.
Re: Ask HN: Elizabeth Holmes has 200 patents – if tech didn't work, why not noticed?
#79Earlier quoted context omitted.
She could try, but the patents might be found to be 'non-enabling' and thus invalid. Patents are supposed to teach a reader how to make the invention. In particular, it seems that the microfluidics stuff needs new inventions to make it work in practice. So presumably those aren't described in the patents. Although it wouldn't be the first time that management overlooked solutions provided by their own researchers.
Are patents _required_ to teach a reader how to make the invention? That seems like an interesting requirement that I hadn't heard of before, and I've got a patent with my name on it myself.
Re: Ask HN: Elizabeth Holmes has 200 patents – if tech didn't work, why not noticed?
#80Earlier quoted context omitted.
There are thousands of patents for perpetual motion machines. An invention must be novel, useful and non-obvious to be patentable, but it doesn't actually have to work. https://patents.google.com/?q="perpetual+motion"
I thought perpetual motion machines claims were automatically denied. I know they were back in the 1970s when my dad worked at the patent office.
I think the current policy is they are only patentable if there is a working unit that runs for at least a year when left alone in the patent office.