I have been in this exact place before. For the two of them, this day will be just about the worst of their lives. This is ordinarily when hard-core criminals are taken into custody. If their experience was like mine, they had to show up in front of a magistrate with their lawyers, plead not guilty, then go to a dungeon for about 30 minutes while they get handcuffed, fingerprinted, mugshotted, and DNA-swabbed. Then,…
The craziest part of the justice system is how dependent on money it is. I am in a weekly support group for people with the same offense category as me, sometimes crimes not as bad as mine. Most of the members in this group are working class - hourly jobs, no savings, no emergency funds, government lawyers. They mostly had to serve time, had to register as offenders, have strict stipulations. Meanwhile I was able to…
U.S. Files Criminal Charges Against Theranos’s Elizabeth Holmes, Ramesh Balwani
451–460 of 533 posts
Re: U.S. Files Criminal Charges Against Theranos’s Elizabeth Holmes, Ramesh Balwani
#452http://www.paulgraham.com/founders.html 4. Naughtiness Though the most successful founders are usually good people, they tend to have a piratical gleam in their eye. They're not Goody Two-Shoes type good. Morally, they care about getting the big questions right, but not about observing proprieties. That's why I'd use the word naughty rather than evil. They delight in breaking rules, but not rules that matter. This qu…
Re: U.S. Files Criminal Charges Against Theranos’s Elizabeth Holmes, Ramesh Balwani
#453Earlier quoted context omitted.
Are you implying that the bankers should go to jail for the misrepresentations made by the applicant because they didn’t exercise an “appropriate” level of diligence?
No, IIRC from reports years back, there is considerable evidence that this kind of fraud was not often not initiated by applicants but encouraged by lender agents, who were in turn encouraged by lender policies and incentive structure, which was set by lender executives. This isn't lack of diligence, this is setting a policy with reasonably foreseeable consequences.
It's massively unethical and it feels like people should be in jail, but proving actual crime took place during the lead-up to the recession would be a massive undertaking with little satisfaction as payout, and just as many run-of-the-mill home buyers going to jail as lender associates or executives.
Re: U.S. Files Criminal Charges Against Theranos’s Elizabeth Holmes, Ramesh Balwani
#454Re: U.S. Files Criminal Charges Against Theranos’s Elizabeth Holmes, Ramesh Balwani
#455Earlier quoted context omitted.
They had a good idea of what they wanted to do (blood tests using very thin needles) but never successfully figured out how to accomplish that with the level of accuracy required. Most Medical professionals believe that what they wanted to do was simply impossible from a biological perspective due to the natural variations of blood content. It would have been like trying to determine traffic on a freeway by taking a…
Well stated. I'm a retired neurosurgical anesthesiologist who relied on accurate blood test results to manage major intracranial procedures. No way would I accept a finger-stick hemoglobin/hematocrit as the basis on which to decide on the need for blood transfusion. Why? Because as a medical intern I did them routinely, because I had to get a number to present at morning rounds and even our excellent STAT Lab (LAC-US…
Re: U.S. Files Criminal Charges Against Theranos’s Elizabeth Holmes, Ramesh Balwani
#456Earlier quoted context omitted.
I think medical-related crimes are very different. Especially when they directly affect patients. Few people have gotten away with fraud on the cash side in this industry though. Valeant Phamaceuticals. Shkreli
> Few people have gotten away with fraud on the cash side in this industry though. Valeant Phamaceuticals. Shkreli I don't think Shkreli was defrauding regarding his pharmaceutical practices. (though he has security charges). He was using shady practices that were totally legal. Completely different game.
Re: U.S. Files Criminal Charges Against Theranos’s Elizabeth Holmes, Ramesh Balwani
#457"Wire fraud" - it's amazing the litany of things one can do, and ultimately get caught up in this specific basket. Al Capone went down for tax evasion ...
Re: U.S. Files Criminal Charges Against Theranos’s Elizabeth Holmes, Ramesh Balwani
#458>Theranos’s investors, most of whom poured money into the company after its commercial rollout in Walgreens stores in late 2013, have collectively lost nearly $1 billion. They include the Waltons, heirs to Walmart Inc. founder Sam Walton, media mogul Rupert Murdoch, Atlanta’s Cox family and the family of Betsy DeVos, the Secretary of Education. Each invested more than $100 million in Theranos—investments that are now…
Re: U.S. Files Criminal Charges Against Theranos’s Elizabeth Holmes, Ramesh Balwani
#459Earlier quoted context omitted.
And for everyone one of those I can find about a thousand HN comments telling you to push on even if you're unsure about whether you can deliver. Edit: For that reason, most of this "I told you so" sounds like hindsight bias if it comes from someone who would normally take the attitude of "fake it till you make it", "don't wait until you're sure you have a working product".
Look at my comments on the April thread. I was incredibly sceptical about a 19 year old with no experience starting a biotech company. All of my comments had a large number of upvotes (for 2015), while many of the people disagreeing with me were downvoted into the negatives.
The hard part is to do it in a way consistent with the rhetoric about “fake it till you make it”/“it’ll all work out”/“all self doubt is impostor syndrome”.
Re: U.S. Files Criminal Charges Against Theranos’s Elizabeth Holmes, Ramesh Balwani
#460Does anybody know if Theranos got started with at least an idea how to accomplish what they wanted to do? From what I have heard in interviews they started with the thought "Doing xxx would be super useful" but didn't have an approach for accomplishing this but instead took in money and tried to figure it out. It's like me saying "An antimatter drive would revolutionize space exploration" and starting to collect mone…
Holmes and Balwani had some experience with microfluidics (IIRC), which is certainly sufficient chemical background to give them a credible belief that they could do what they wanted to do (run blood tests on smaller sample sizes). The ultimate problem with their goal is that when you do a finger prick, a large fraction of the sample is not blood but interstitial fluid and skin layers, which makes the results noisy a…