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Caffeine dosing strategies to optimize alertness during sleep loss

onlinelibrary.wiley.com

11–20 of 229 posts

Re: Caffeine dosing strategies to optimize alertness during sleep loss

#11

Surely there’s a better drug than coffee for staying awake for a long time.

There is though maybe not legally, for example the wide range of amphetamines. There has been a lot of research into this for fighter pilots[1].

[1] https://en.wikipedia.org/wiki/No-go_pill

Re: Caffeine dosing strategies to optimize alertness during sleep loss

#13
post #9

Is there the TLDR version of this paper?

The summary on the first page?

I think he/she is asking for a more actionable summary. E.g. consume 10mg of caffeine every 4 hours from 6am till 2pm etc.

Re: Caffeine dosing strategies to optimize alertness during sleep loss

#17
post #4
post #2

> Caffeine, if safely administrated, is an effective countermeasure to mitigate impairment of alertness caused by sleep loss. This has been demonstrated in multiple laboratory and field studies for different sleep–wake schedules. However, to maximize its effectiveness, caffeine should be consumed at the right time and amount. Here, we developed an optimization algorithm to determine when and how much caffeine to cons…

They built their own tabu search algorithm (section 2.3)

How large is the search space?

Re: Caffeine dosing strategies to optimize alertness during sleep loss

#18
post #14

Surely there’s a better drug than coffee for staying awake for a long time.

Modafinil - https://en.wikipedia.org/wiki/Modafinil

I took some of that once for an overnight deployment at work. It's good stuff. No headaches like I would have got if I'd been drinking coffee all night.

Re: Caffeine dosing strategies to optimize alertness during sleep loss

#19
Club mate is the drink of choice in the start up community in Berlin. I've made the mistake of drinking that in the evening a couple of times and regretted that at 4am by being wide awake and unproductive the next day. If you are not familiar, mate tea which this is based on contains a form of caffeine that is particularly potent. It's like drinking multiple espresso shots. Don't drink this if you have blood pressure issues.

In general, I've learned to moderate my caffeine intake and restrict myself to mornings only. The more you consume, the more you need of it to work at all, and the more likely you are to have side effects like feeling tired, having poor sleep rythm, headaches, etc.

When used in moderation it's a great tool for getting yourself productive after a lazy weekend on a monday morning. However, if you feel tired all the time, stop drinking coffee and get a few nights of good sleep in.

Re: Caffeine dosing strategies to optimize alertness during sleep loss

#20

Surely there’s a better drug than coffee for staying awake for a long time.

The Germans used metamphetamine during World War 2. They gave it nicknames Panzerschokolade ("tank chocolate"), Stuka-Tabletten ("Stuka tablets"), Herman-Göring-Pillen, or Flieger-Marzipan ("pilot's marzipan"). It was freely available under the brand name "Pervitin" until 1941. From then on, you needed a prescription in order to purchase it.
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