Earlier quoted context omitted.
For my entire career (I'm a lifelong Londoner) I've been bemused by newcomers to the city who essentially refuse to even consider living beyond zone 2. I grew up on the border of Z3/4 and now live in Z6, but have worked either in zone 1 or beyond it (in travel terms) since late 1996. My gut feeling is that the horrific prices in the centre are very much tied to what seems to be a perception that the outskirts suck.
I knew a woman in her 50s in London that was commuting daily 6 hours from one of the outskirts to another outskirt on the opposite side for a low-paying SWEng job. Frankly, why do people even bother moving to London/UK? Unless you are a finance person, a money-laudering crook from abroad or a top-school PhD in a hot field, your prospects are slim.
Luckily there's a lot of tech work is in or close to the East (Shoreditch, City), so I can live in the South East.
If I had to commute to west, I'd probably look to move to the outskirts on the west.