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Goldman Sachs questions whether curing patients is a sustainable business model

arstechnica.com

141–150 of 376 posts

Re: Goldman Sachs questions whether curing patients is a sustainable business model

#141
post #2

Thats why "we the people" need to have large part in developing new drugs and the care of people, this is nothing that can be left to the "market" in some hope that it will "work out".

You dont seem to be aware that public universities are already heavily involved in drug development. Looking at the facts is helpful before building a narrative.

Re: Goldman Sachs questions whether curing patients is a sustainable business model

#142
post #87

Earlier quoted context omitted.

> Creating a public institution with no pressure to make profit is a disaster waiting to happen. This is the model many rich country healthcare runs on, and provides measurably better outcomes for less expenditure than the US.

I may be ignorant on this, but don't many of those countries benefit by the r&d funding happening in the US?

Some of the extra money does go to R&D (though that's somewhat misleading: a lot of "R&D" spending is unnecessary duplication of safety trials because the FDA doesn't recognise any foreign medical safety standards, not even e.g. the EU). But a substantial chunk of it is wasteful inefficiencies due to multiple layers of middlemen (there are typically 5 layers between the insurance company that's paying and the company that makes the drug/device) with opaque pricing structures (there are hidden rebates in both directions at every one of those layers). National healthcare systems still have bureaucratic inefficiencies but they do avoid having intermediaries with a direct incentive to bamboozle each other.

Re: Goldman Sachs questions whether curing patients is a sustainable business model

#143

The industry is being defined too narrow. The full industry includes insurers. Insurers have every reason to cure patients. Cured patients live longer. The longer you live the more years you pay premiums. The more premiums the higher your profits. So insurance is incenivized to put the money in the hands of those who cure rather than those who require insurance to fork up a fixed amount on an ongoing basis.

Do insurance companies really have this incentive? You can (and probably will) shop around and find a new insurer within a few years.

Re: Goldman Sachs questions whether curing patients is a sustainable business model

#144

The 'ideal' drug from a business point of view not only not cures the patient long term, it offer a short term mitigation while increasing the risk on relapse and thus future recurring consumption of the treatment. At the same time it can be IP protected to block alternatives and has an insured third party collective payment coverage to guard against the treated running out of funds to afford the perpetual dependency…

This is wishful thinking because you never know ahead of time what is going to work and certainly not the pharmacodynamics of your drug. Plus your reasonning is false, even with current chronic conditions like RA many companies are exploring different dosages of bio treatments to drive remission instead of lifetime treatment.

Re: Goldman Sachs questions whether curing patients is a sustainable business model

#145
post #54

The 'ideal' drug from a business point of view not only not cures the patient long term, it offer a short term mitigation while increasing the risk on relapse and thus future recurring consumption of the treatment. At the same time it can be IP protected to block alternatives and has an insured third party collective payment coverage to guard against the treated running out of funds to afford the perpetual dependency…

So we agree medicine cannot be managed as a business, right? It's ok if healthcare losses money, in fact it should be ok for all public sevices to operate and not being profitable.

Why is that ok if a private actor can do it better and cheaper? Most cases for public services are not really based on any good justification. On the contrary accepting that they lose money from the get go will drive soviet style inflation of resources and bankruptcy in the long run. Its been tried.

Re: Goldman Sachs questions whether curing patients is a sustainable business model

#146
post #126

Earlier quoted context omitted.

"Creating a public institution with no pressure to make profit is a disaster waiting to happen." Why? Schools are not for-profit institutions (well, not everywhere). Police don't make a profit. Nor does the fire brigade. Or the military, for that matter. Are all of these disasters waiting to happen?

You have never heard of private military companies? They are extensively used byvthe US mostly for non combat situations. They are very effective, for profit, and much less costly than the regular army.

That a private company works better at some locations does not imply logically that a public institution is a disaster waiting to happen, which was the original claim.

Let's make it a bit more ridiculous and extreme. Would it be a good idea to privatize US nukes? What would profit incentive provide there?

Remember, we are discussing the claim "creating public institutions without a profit incentive is a disaster waiting to happen".

Re: Goldman Sachs questions whether curing patients is a sustainable business model

#147
post #54

Earlier quoted context omitted.

So we agree medicine cannot be managed as a business, right? It's ok if healthcare losses money, in fact it should be ok for all public sevices to operate and not being profitable.

Why is that ok if a private actor can do it better and cheaper? Most cases for public services are not really based on any good justification. On the contrary accepting that they lose money from the get go will drive soviet style inflation of resources and bankruptcy in the long run. Its been tried.

That hasn't happened in the United Kingdom with the NHS

Re: Goldman Sachs questions whether curing patients is a sustainable business model

#148

Earlier quoted context omitted.

You are jumping from one extreme to the other. Creating a public institution with no pressure to make profit is a disaster waiting to happen. You can certainly keep a 'competitive' environment which is regulated with incentives. And I do agree healthcare needs this, and shouldn't live purely by the free market.

> Creating a public institution with no pressure to make profit is a disaster waiting to happen. This is the model many rich country healthcare runs on, and provides measurably better outcomes for less expenditure than the US.

lol you are acting like the rest of the world is developing medecines. The US market is the driving force for 95 percent of drugs developed worldwide, by a very, very wide margin. This is not random.

Re: Goldman Sachs questions whether curing patients is a sustainable business model

#149
post #117
post #87

Earlier quoted context omitted.

I may be ignorant on this, but don't many of those countries benefit by the r&d funding happening in the US?

It's all multinational these days. Only 4/10 of the big players are in the US https://www.tharawat-magazine.com/facts/10-largest-pharmaceu... and that's quite logic if you remember that the European market is pretty much harmonized and twice as populated as the US.

The EU market is far from being harmonized medecines regulation wise. it always takes longer to get approval across all EU countries vs one approval in the US. Pricing of drugs is not harmonized at the EU level either and thats a hard block for any launch.

Re: Goldman Sachs questions whether curing patients is a sustainable business model

#150

The health industry has no reason to cure patients. On the contrary, they have reasons to create new patients. And it's across the board. I tell myself exactly that when I look at my toothbrush. A toothbrush lasts about ~3 weeks before needing replacing. I'm sure someone in the industry will tell me that it's because it's made of unobtainium unicorn hair specially designed to make my teeth whiter and all that. I also…

This is where traditional Chinese medicine got it right : they have a culture of trying to keep people healthy. You are supposed to go to the doctor to not become sick. It's maintenance. Not that I think it's better, but economically, you suddenly have the same goal as your clients. And that more sane.

Too bad the medicine part of TCM is junk science
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