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Many People Taking Antidepressants Discover They Cannot Quit

nytimes.com

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Re: Many People Taking Antidepressants Discover They Cannot Quit

#231

Post by rotexo »

himom wrote: post #131

I was on 60mg/day Remeron (mirtazapine) for 9 years but discontinued due to decline in its effects. Tried a bunch of the remaining medications, found trintellix which ups anxiety 5x but addresses depression. Taking hydroxyzine as needed for anxiety now. During taper symptoms: - nausea - general anxiety After taper symptoms (continue today): - general anxiety - strong, brief muscle contractions anywhere in my body (my…

I am currently on mirtazapine, and this article is prompting me to look into tapering off the drug. I would much appreciate any advice you would give on the process, and any other considerations you can think of that I should be aware of.

Re: Many People Taking Antidepressants Discover They Cannot Quit

#232

Post by NPMaxwell »

Nomentatus wrote: post #205
NPMaxwell wrote: post #141

Earlier quoted context omitted.

The Cipriani study is a nice meta-analysis: "The random-effects summary SMD for all antidepressants was 0·30" This site explains SMD: http://handbook-5-1.cochrane.org/chapter_9/9_2_3_2_the_stand... . This site shows what 0.3 looks like (actually shows 0.2 and 0.5): http://rpsychologist.com/short-r-script-to-plot-effect-sizes... . Typically, when people are summarizing this line of research saying that there is no eff…

But note that there's no attempt to control for the (extremely strong) anti-histamine effects of these drugs (particularly elavil.) You need to test them against other anti-histamines which can also improve apparent health, a lot.

Fascinating idea!

Re: Many People Taking Antidepressants Discover They Cannot Quit

#233

Post by jonhendry18 »

StanislavPetrov wrote: post #186

>The drugs have helped millions of people ease depression and anxiety, and are widely regarded as milestones in psychiatric treatment. History is littered with harmful, poorly-thought out "psychiatric treatments" that were widely regarded as milestones. Even if there are a tiny minority of people who's mental condition is so bad that scrambling their brain with drugs will lead to an "improvement", the widespread reli…

CCHR is Scientology. You sure you want to believe them?
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