The enemy within: Gut bacteria drive autoimmune disease
sciencedaily.com
The enemy within: Gut bacteria drive autoimmune disease
1–10 of 87 posts
Re: The enemy within: Gut bacteria drive autoimmune disease
#2Is the suggestion that this particular bacteria is behind all forms of systemic lupus or merely that this bacteria can cause such a response? Thats an important difference.
Re: The enemy within: Gut bacteria drive autoimmune disease
#3Is the suggestion that this particular bacteria is behind all forms of systemic lupus or merely that this bacteria can cause such a response? Thats an important difference.
Similarly, this headline makes it sound like all autoimmune diseases stem from gut bacteria. That sounds unlikely.
Re: The enemy within: Gut bacteria drive autoimmune disease
#4Is the suggestion that this particular bacteria is behind all forms of systemic lupus or merely that this bacteria can cause such a response? Thats an important difference.
Similarly, this headline makes it sound like all autoimmune diseases stem from gut bacteria. That sounds unlikely.
Quote “the research team found that they could suppress autoimmunity in mice with an antibiotic or a vaccine aimed at E. gallinarum.”
The titles vague to the point of clickbait.
On topic, there is much going on with bacteria. My hunch is this could be a large research area for the next couple decades. We’re talking about a system composed of trillions of individuals and an unknown (but large) number of species and all their interactions. I’m sure there will be bacterial “combinations” that in certain situations are helpful and others deadly, for instance.
Re: The enemy within: Gut bacteria drive autoimmune disease
#5Is the suggestion that this particular bacteria is behind all forms of systemic lupus or merely that this bacteria can cause such a response? Thats an important difference.
Similarly, this headline makes it sound like all autoimmune diseases stem from gut bacteria. That sounds unlikely.
Having one autoimmune disease increases the likelihood that you have or will develop another one. They also have cross-reactivity on tests.
For instance, false positives on the TTG/IGA for celiac are 2% for healthy patients, but rise to 20% for subjects with type 1 diabetes.
Celiac patients have a drastically higher rate of Hashimoto’s, autoimmune thyroid disease: https://www.newsmax.com/t/newsmax/article/718160?keywords=ce... and also the liver disease cited in the article: https://www.verywell.com/celiac-disease-and-liver-diseases-5...
Celiac patients also suffer higher rates of MS: https://multiplesclerosisnewstoday.com/2015/05/14/celiac-dis... MS doesn’t seem gut related on the surface, but you can get almost identical neurological symptoms from celiac. I know because this is what drinking beer does to me.
So, the roots of all of these diseases could definitely be related.
Re: The enemy within: Gut bacteria drive autoimmune disease
#6My mom has Hashimoto’s which she's managed successfully for years using a low daily dosage of doxycycline. This suggests a mechanism for why that seems to work for her.
Re: The enemy within: Gut bacteria drive autoimmune disease
#7My mom has Hashimoto’s which she's managed successfully for years using a low daily dosage of doxycycline. This suggests a mechanism for why that seems to work for her.
Did her endocrinologist prescribe her antibiotic?
I'm asking this because I have Hashimoto's myself and none of the endocrinologists I've seen recommended anything else besides levothyroxine.
Re: The enemy within: Gut bacteria drive autoimmune disease
#8My mom has Hashimoto’s which she's managed successfully for years using a low daily dosage of doxycycline. This suggests a mechanism for why that seems to work for her.
Did her endocrinologist prescribe her antibiotic? I'm asking this because I have Hashimoto's myself and none of the endocrinologists I've seen recommended anything else besides levothyroxine.
Depends on the pharma rep in their area.
Re: The enemy within: Gut bacteria drive autoimmune disease
#9See the paper here: https://sci-hub.tw/downloads/2c98/10.1126@science.aar7201.pd...
Re: The enemy within: Gut bacteria drive autoimmune disease
#10My mom has Hashimoto’s which she's managed successfully for years using a low daily dosage of doxycycline. This suggests a mechanism for why that seems to work for her.
Did her endocrinologist prescribe her antibiotic? I'm asking this because I have Hashimoto's myself and none of the endocrinologists I've seen recommended anything else besides levothyroxine.
No, she and my dad just did their own research online and gave it a try. Seems to have worked out really well for her. Her goiter shrank and she had to reduce her thyroid meds.
Low dose doxycycline seems who tolerated, and has an interesting side effect of reducing inflammation to near zero in the body (CRP levels of actually zero). Given the role of inflammation in heart disease, that might be helpful for longevity too.
There's actually a drug, periostat that's prescribed in this way for oral health. It's 20mg doxycycline taken daily long term. There are studies on it available online.