Autism's social deficits in animal model are reversed by an anti-cancer drug
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Re: Autism's social deficits in animal model are reversed by an anti-cancer drug
#2Another HDAC inhibitor that works against autism and is easy to obtain by eating broccoli sprouts is sulforaphane: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672987/
Re: Autism's social deficits in animal model are reversed by an anti-cancer drug
#3An obvious question is whether this could also be used as a nootropic by non-autistic individuals, and what effect (if any) it would have.
Re: Autism's social deficits in animal model are reversed by an anti-cancer drug
#4An obvious question is whether this could also be used as a nootropic by non-autistic individuals, and what effect (if any) it would have.
> what effect (if any) it would have
super charisma
Re: Autism's social deficits in animal model are reversed by an anti-cancer drug
#5Another HDAC inhibitor that works against autism and is easy to obtain by eating broccoli sprouts is sulforaphane: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672987/
Wow this is really interesting. Any sources on possible mechanisms of action?
Re: Autism's social deficits in animal model are reversed by an anti-cancer drug
#6Another HDAC inhibitor that works against autism and is easy to obtain by eating broccoli sprouts is sulforaphane: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672987/
But note that according to [1], sulforaphane inhibits HDAC6, whereas the article speaks of HDAC2.
Re: Autism's social deficits in animal model are reversed by an anti-cancer drug
#7Another HDAC inhibitor that works against autism and is easy to obtain by eating broccoli sprouts is sulforaphane: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672987/
So little research is done on Autism from the perspective of adults living on the spectrum - almost all the funding and research seems to go towards childhood and to give parents coping mechanisms.
IMO we need clear clinical definitions of different parts of the spectrum so we can have more intelligent conversations about it - is a study cohort involving 10 year olds ones who cannot clothe themselves or participate in regular school activities, or ones which have some social reading deficits but can still participate? Its always very difficult to tell.
Re: Autism's social deficits in animal model are reversed by an anti-cancer drug
#8An obvious question is whether this could also be used as a nootropic by non-autistic individuals, and what effect (if any) it would have.
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Re: Autism's social deficits in animal model are reversed by an anti-cancer drug
#9Another HDAC inhibitor that works against autism and is easy to obtain by eating broccoli sprouts is sulforaphane: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672987/
So little research is done on Autism from the perspective of adults living on the spectrum - almost all the funding and research seems to go towards childhood and to give parents coping mechanisms. IMO we need clear clinical definitions of different parts of the spectrum so we can have more intelligent conversations about it - is a study cohort involving 10 year olds ones who cannot clothe themselves or participate i…
[deleted]
Re: Autism's social deficits in animal model are reversed by an anti-cancer drug
#10An obvious question is whether this could also be used as a nootropic by non-autistic individuals, and what effect (if any) it would have.
> what effect (if any) it would have super charisma
Eh, maybe… but I am reminded of the observation that if a single tweak could significantly enhance mental abilities, evolution would have probably given it to us already. I think Eliezer Yudkowsky has a longish piece to this effect (please forgive me if I am mis-remembering).