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How exercise in old age prevents the immune system from declining

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51–60 of 68 posts

Re: How exercise in old age prevents the immune system from declining

#51
If you work at a desk all day and are interested in being more active, take a look at Desk Cycle:

https://deskcycle.com/

I got one a few months ago after reading a testimonial in a similar thread here on hacker news. Mine sits permanently under my desk. I have nothing but positive comments to say about it. Fit's nicely under the desk, works wonderfully.

Re: How exercise in old age prevents the immune system from declining

#52
post #31

Earlier quoted context omitted.

Not only a saying: science. As long as you can walk 1.36 m/s (about 5 km/hour), the grim reaper will never catch up with you. 0.82 m/s (about 3km/hour) already makes you mostly safe ( http://www.bmj.com/content/343/bmj.d7679 )

It's nice to see an editor for the BMJ (formerly British Medical Journal) has a sense of humor. I wasn't expecting to see Pratchett T. as the first citation in a (somewhat) serious medical journal article.

The BMJ Christmas issue traditionally is for (somewhat) serious science, presented funnily. https://www.medicalnewstoday.com/articles/320319.php has some examples.

Re: How exercise in old age prevents the immune system from declining

#53

If you work at a desk all day and are interested in being more active, take a look at Desk Cycle: https://deskcycle.com/ I got one a few months ago after reading a testimonial in a similar thread here on hacker news. Mine sits permanently under my desk. I have nothing but positive comments to say about it. Fit's nicely under the desk, works wonderfully.

Looks good for perpetual foot-tappers, too.

Would be good if it could generate power...maybe charge up a device a bit in the process.

Re: How exercise in old age prevents the immune system from declining

#54

Earlier quoted context omitted.

I do a ~24 hour fast weekly, and a LOT of sites go into this "burning off garbage" or "toxin cleaning" rhetoric which always puts me in "bullshit warning" mode. Is there actual science behind these claims?

Fat tissue is a collector of some kinds of toxins (don't remember exactly which now) and some heavy metals (heh). Going into fat burning actually releases these into your system (which should be bad, though)

Are you thinking of https://en.wikipedia.org/wiki/Persistent_organic_pollutant ?

Re: How exercise in old age prevents the immune system from declining

#55

On a 5 hr bike ride your body is going to go into a similar state as intermittent fasting with all your glycogen being burned off. Similar to fasting this frees up energy and allows the garbage in your system to be burned off.

I do a ~24 hour fast weekly, and a LOT of sites go into this "burning off garbage" or "toxin cleaning" rhetoric which always puts me in "bullshit warning" mode. Is there actual science behind these claims?

Years ago I attended a health seminar where the presenter stated that the digestive system uses lots of energy to digest food. He (and other authors I've read) suggested the idea that generally speaking, when your body doesn't have to spend energy digesting it can do other things better. (ie, detox would fit in with this) Though I can't say I understand how or why this would work, it's seems a reasonable assumption.

Re: How exercise in old age prevents the immune system from declining

#56
post #18

I have a concern. A few months ago, a widely publicized study[1] indicated that moderate-to-large amounts of exercise caused a buildup of plaque in the hearts of middle-aged white men. This correlation was not seen in any women, nor was it seen in black men. Unfortunately, this study included no Indian nor Southeast Asian people. I've seen unrelated studies indicating similar health outcomes for white men and Indian…

Not even middle-aged white men should worry about it. It was more "This population had the highest coronary artery calcification, which matches what other studies have found. We should look into it more" rather than "These white dudes gotta slow down or their hearts'll give out".

Re: How exercise in old age prevents the immune system from declining

#57

On a 5 hr bike ride your body is going to go into a similar state as intermittent fasting with all your glycogen being burned off. Similar to fasting this frees up energy and allows the garbage in your system to be burned off.

I do a ~24 hour fast weekly, and a LOT of sites go into this "burning off garbage" or "toxin cleaning" rhetoric which always puts me in "bullshit warning" mode. Is there actual science behind these claims?

These kinds of claims when made about fasting are IME usually talking about autophagy. https://www.niddk.nih.gov/news/archive/2013/working-out-heal... is the least shady synopsis I could find. That mainly talks about exercise - for fasting, people seem to be most interested in the mTOR pathway. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266408/figure/...

I'm not qualified to judge the literature as a whole, and it appears to be an open question whether this can be translated to actionable advice, but we're not in complete bullshit territory here.

Re: How exercise in old age prevents the immune system from declining

#58
post #43

Earlier quoted context omitted.

I do a ~24 hour fast weekly, and a LOT of sites go into this "burning off garbage" or "toxin cleaning" rhetoric which always puts me in "bullshit warning" mode. Is there actual science behind these claims?

The 'detox' side of it is very likely garbage (but a great way to sell); on the other hand, 5-hour bike rides without fuel will deplete your glycogen stores and there'll come a point where the differnce becomes obvious (see 'bonk-training'). A 24-hour fast is different; your body will burn fat at sufficient rate to avoid glycogen depletion (it's pretty simple; the harder you exercise the less energy comes from fat an…

In one of his articles Ray Cronise gave some numbers that even with light jogging or even fast walking for fuel body uses carbohydrates exclusively. So cardio exercises are a bad way to loose weight. They made people hungry. And as people eat all the fat from the food is stored as body fat and may not be burned until the next exercise.

Re: How exercise in old age prevents the immune system from declining

#59

Earlier quoted context omitted.

I do a ~24 hour fast weekly, and a LOT of sites go into this "burning off garbage" or "toxin cleaning" rhetoric which always puts me in "bullshit warning" mode. Is there actual science behind these claims?

Years ago I attended a health seminar where the presenter stated that the digestive system uses lots of energy to digest food. He (and other authors I've read) suggested the idea that generally speaking, when your body doesn't have to spend energy digesting it can do other things better. (ie, detox would fit in with this) Though I can't say I understand how or why this would work, it's seems a reasonable assumption.

I read some Russian articles about research carried out about 40 years ago about the most efficient way to survive on limited food if one gets lost in wild nature. Their conclusion was that one should not ration food. One should just eat normally until one runs out of food and then fast until normal amount of food is available. And fast here means literally zero calories. One should not eat berries, mushrooms etc. Those triggers digestion that spend more energy that will be extracted from snacks.

Re: How exercise in old age prevents the immune system from declining

#60
post #18

I have a concern. A few months ago, a widely publicized study[1] indicated that moderate-to-large amounts of exercise caused a buildup of plaque in the hearts of middle-aged white men. This correlation was not seen in any women, nor was it seen in black men. Unfortunately, this study included no Indian nor Southeast Asian people. I've seen unrelated studies indicating similar health outcomes for white men and Indian…

Not even middle-aged white men should worry about it. It was more "This population had the highest coronary artery calcification, which matches what other studies have found. We should look into it more" rather than "These white dudes gotta slow down or their hearts'll give out".

I appreciate your response. I’m under the impression that the white men who exercised more had more calcification:

> Instead, Laddu and her colleagues found that participants in trajectory group three, or those who exercised the most, were 27 percent more likely than those in trajectory group one to develop CAC by middle age. CAC was measured during the participants’ 25th year in the study using computed tomography, a CT scan, of the chest. At year 25, participants were ages 43 to 55.

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