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Protein that destroys HIV discovered

loyolamedicine.org

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Re: Protein that destroys HIV discovered

#51

Post by mhb »

Ardit20 wrote: post #32
mhb wrote: post #26

Earlier quoted context omitted.

I'm sure the vast majority of the readers of this article have also not heard of a $10K, $100K or $700K microscope either which is why it's incongruous to have the price in the first sentence of the article without any context. Here are many other microscopes the prices of which you may not have heard. Is it enlightening? http://www.technicalsalessolutions.com/

There are only seven microscopes there which are more expensive. This is journalism of course, but there is no need to discredit everything simply because you can word it in such a way as to make it sound stupid. Personally, once the sum for the microscope was mentioned I was able to judge that the research is quite serious, has the latest technology and advantages of the latest technology and thus give me more confi…

The point is that there are a range of microscope prices. The one they used falls somewhere in the spectrum of prices of lab microscopes I'd expect scientists to be using routinely. Mentioning it in the lead sentence of the article makes it seem notable for some reason. Maybe it is, but it's impossible to know without any context.

Aside from its price, does it have some unusual capability that enabled them to make this discovery? That is the kind of fact which would make the article more informative. When it's possible to image molecules with a device you can build for under $100, knowing the cost of the equipment someone used isn't very useful. It's analogous to an argument from authority.

Re: Protein that destroys HIV discovered

#52

Post by Ardit20 »

mhb wrote: post #51
Ardit20 wrote: post #32

Earlier quoted context omitted.

There are only seven microscopes there which are more expensive. This is journalism of course, but there is no need to discredit everything simply because you can word it in such a way as to make it sound stupid. Personally, once the sum for the microscope was mentioned I was able to judge that the research is quite serious, has the latest technology and advantages of the latest technology and thus give me more confi…

The point is that there are a range of microscope prices. The one they used falls somewhere in the spectrum of prices of lab microscopes I'd expect scientists to be using routinely. Mentioning it in the lead sentence of the article makes it seem notable for some reason. Maybe it is, but it's impossible to know without any context. Aside from its price, does it have some unusual capability that enabled them to make th…

I understand finely why your criticism might be a valid point, however, when all comments take the same shade that your criticism does, we start looking for the trees and miss the forest.

If you can build something for $100, yet the same thing they used costed $250,000 to build, ok let us even say for good measure it costed $25,000 and the rest was inflated, compared to $100 it must be a well awesome product, way superior than what you could build, ten times, 25 times, and if we are to trust the actual figure, 250 times better than what you could built.

The point of the article is most probably that it is the latest technology anyway. I mean, it is fine to look out for these flaws, but something much grater happened there, they actually discovered something. If all we get from comments is flaws flaws and the opposite down voted, then this community simply is not working.

Re: Protein that destroys HIV discovered

#53

Post by mhb »

Ardit20 wrote: post #52
mhb wrote: post #51

Earlier quoted context omitted.

The point is that there are a range of microscope prices. The one they used falls somewhere in the spectrum of prices of lab microscopes I'd expect scientists to be using routinely. Mentioning it in the lead sentence of the article makes it seem notable for some reason. Maybe it is, but it's impossible to know without any context. Aside from its price, does it have some unusual capability that enabled them to make th…

I understand finely why your criticism might be a valid point, however, when all comments take the same shade that your criticism does, we start looking for the trees and miss the forest. If you can build something for $100, yet the same thing they used costed $250,000 to build, ok let us even say for good measure it costed $25,000 and the rest was inflated, compared to $100 it must be a well awesome product, way sup…

Readers of a peer-reviewed article are, I think, willing to stipulate that the authors of the article are using adequate equipment. Probably most of the researchers of submitted articles which the reviewers criticize or reject use the same equipment.

The price of the equipment is not a factor in the credibility of the work. It does not make it more or less credible or flawed in any way. It is unusual to see the price of the lab equipment mentioned - that's all.

Re: Protein that destroys HIV discovered

#54

Post by sprout »

Ardit20 wrote: post #50
sprout wrote: post #46

Earlier quoted context omitted.

I went to a ~3000 student private liberal arts college and we subscribed to a handful. 90% of what I needed was out of reach. I suspect there are some economies of scale, but those economies are completely artificial; there's no reason the per-student rate should be different for a small college than a large one. Well, I suppose there is one: most of the cost is administrative overhead in actually collecting the bill…

What you needed, not the students.

I was a student (now graduated). And I was not alone in lacking needed resources. I had numerous friends in other departments who complained of lacking needed journal articles.

Re: Protein that destroys HIV discovered

#55

Post by Ardit20 »

mhb wrote: post #53
Ardit20 wrote: post #52

Earlier quoted context omitted.

I understand finely why your criticism might be a valid point, however, when all comments take the same shade that your criticism does, we start looking for the trees and miss the forest. If you can build something for $100, yet the same thing they used costed $250,000 to build, ok let us even say for good measure it costed $25,000 and the rest was inflated, compared to $100 it must be a well awesome product, way sup…

Readers of a peer-reviewed article are, I think, willing to stipulate that the authors of the article are using adequate equipment. Probably most of the researchers of submitted articles which the reviewers criticize or reject use the same equipment. The price of the equipment is not a factor in the credibility of the work. It does not make it more or less credible or flawed in any way. It is unusual to see the price…

We were not reading a peer reviewed article.

Re: Protein that destroys HIV discovered

#56

Post by b-man »

Ardit20 wrote: post #38
jonknee wrote: post #35

Earlier quoted context omitted.

> Why should there be grant money set aside to cover peer review? Just ask yourself honestly and try to be unbiased, is that not a very selfish proposition? Why should there be grant money set aside to cover research? I don't think I'm alone in finding that it's frustrating to have tax payer funded research be hidden behind paywalls that other tax payer funded institutions can access but the general public cannot. We…

Those who are interested in the goods however, subsidise those goods. You, or the tax paying public is not interested in those goods, but only the results. Just bare in mind this is only one article. There are thousands of other articles which you personally, let alone the tax paying public cares nothing of. Knowledge is useful only to those who know how to make use of it. But my opinion is not wanted, thus, you have…

because perhaps I should say if you had such understanding then you would have the liberty to suggest a better system.

Ask, and Ye Shall Receive

http://mitworld.mit.edu/video/534

Re: Protein that destroys HIV discovered

#57

Post by Devilboy »

Ardit20 wrote: post #48
Ardit20 wrote: post #17

Earlier quoted context omitted.

Ohh right cool, geeks feeling awkward when sex is compared to pleasure? Dude, sex is pleasure, indeed it is one of the highest pleasure! It is not just poor African orphans who get aids. In fact the reason why so much effort is put into it is because it is not just poor African orphans in a far away land. It is you and me and anyone else who could potentially get aids in a drunken night in a club, or park, or maybe e…

Ok, this is a reply to mquander on this thread http://news.ycombinator.com/item?id=1628106 (unfortunately I do not know how to link directly to the post and the reason why I am not replyin there is because I can not. I would not like to see this community as a place where I can validate or discredit the thoughts I already hold. I am only 22 and wish much to grow. In those areas where I might not provisionally want to…

This is completely off topic

Re: Protein that destroys HIV discovered

#58

Post by Ardit20 »

sprout wrote: post #54
Ardit20 wrote: post #50

Earlier quoted context omitted.

What you needed, not the students.

I was a student (now graduated). And I was not alone in lacking needed resources. I had numerous friends in other departments who complained of lacking needed journal articles.

Desirable and necessary resources are different. The entirety of the night in regards to hacker news however has been quite revealing.

This place is no less a waste of time than telly. Your insistence simply proves so. Anyone who has been in a university just knows that they had access to the journals they needed, but perhaps not some they might have wanted to.

Yet regardless, neither helps us in our endeavour. Whether the person publishes all the journal articles, I care little. This is no longer a community. No longer are etiquettes and the culture of the site enforced, it is a play ground instead where populism wins.

That is fine, that is how things have been working. You go there first and leave when so it becomes. Yet I thought naively perhaps that this time it would be different.

It is not. Only in the physical world is it different, only in the physical world do we have the freedom, for in that sphere, nature has had the advantage of many years.

Not even the best and brightest can come even close to it. Though maybe I am just naive to suggest that PG is either of those in regards to the internet. He is of a different generation, of a different age too, in his 40s or 50s, chasing money or whatever he chases.

This is our net to make. Ours to learn the mistakes and implement their solutions.

Long Live Youth perhaps I should have said.

Re: Protein that destroys HIV discovered

#59

Post by aphyr »

tocomment wrote: post #28
freesciencenow wrote: post #11

Paywalls for scientific research are evil. http://209.20.67.195/misc/sastri-identification.pdf (I intend to do this regularly; see bio.)

If you really want to free research you should do this: Investigate whether there is an inverse correlation between the freeness of the journal a paper is published in and its popularity (number of citations?). You should control for the reputation of the journal since that could throw off the results. If you find such a correlation and get it publicized, perhaps that would encourage more researchers to submit to fre…

Impact factor (# of citations per article in journal) tends to be lower for free journals, since a.) the threshold for publication tends to be lower, and b.) the established journals still have prestige, which largely remains the currency on which scientific reputations and tenure are built. Because most of the big journals don't allow you to retain publication rights after publishing with them, anyone who does big-impact research worthy of publication in those journals faces an exclusive choice between prestige, exposure, and selectivity, or opening their work to the public at the cost of "devaluing" their work. It's a real dilemma--one which publishers are trying to exploit for all they can.

The picture is changing (look at the amazing success of the Arxiv), but I think for-profit, paywalled journals are going to be alive and kicking for quite a while.

Re: Protein that destroys HIV discovered

#60

Post by sprout »

Ardit20 wrote: post #49
sprout wrote: post #42

Earlier quoted context omitted.

>On your first point. I was a student and during that time I had access to all the papers I needed, sufficent papers to get the top grades. Where did you go to school? From my experience yours is most atypical. I don't sell applications. I configure and make slight modifications to free applications, or applications my employer pays for (and in my experience the ones that charge have negative value from my perspectiv…

"But yes, reason has little purchase in this place. The community has very strong biases and refuses to give time to opposition." What exactly do you mean?

You're being downvoted purely because people disagree with you. HN is supposed to be above that.
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