Nanopore MinION – $1k solid-state DNA sequencers
nanoporetech.com
Nanopore MinION – $1k solid-state DNA sequencers
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Re: Nanopore MinION – $1k solid-state DNA sequencers
#2Wow. Can I do whole-genome sequencing with this?
Is this a similar product/result as buying whole genome sequencing from an established company for the $500 to $800 they charge these days?
Re: Nanopore MinION – $1k solid-state DNA sequencers
#3So what’s a whole human genome sequence cost? That’s the usual metric machines are listed by.
Re: Nanopore MinION – $1k solid-state DNA sequencers
#4I need one of these to identify the neighbor that lets their dog fertilize my lawn.
At least .. I hope it's a dog.
Re: Nanopore MinION – $1k solid-state DNA sequencers
#5How much are the flow cells?
Re: Nanopore MinION – $1k solid-state DNA sequencers
#6How much are the flow cells?
Ah. ~$500 - $1000 each. That seems like an expensive consumable, but I have no basis for comparison. Is this a lot?
Re: Nanopore MinION – $1k solid-state DNA sequencers
#7For an interesting contrast, here's a look inside two DNA sequencers from the last decade, costing two orders of magnitude more (and also roughly two orders of magnitude larger in volume and weight):
https://www.youtube.com/watch?v=XaumUp4GpCw
https://www.youtube.com/watch?v=3K9whMm7vvc
It's almost like Moore's law.
Re: Nanopore MinION – $1k solid-state DNA sequencers
#8I just ran a couple of flowcells last week. I've ran 8 total so far now. My impression is that it can be very inconsistent depending on the quality of the flowcell that they send you and your DNA prep. Great for smallish genomes (bacteria), not enough throughput/quality for large eukaryotic genomes (1gb+) unless you got money to burn.
Re: Nanopore MinION – $1k solid-state DNA sequencers
#9I remember looking into this device before, but as I recall it was intended for small bacterial genomes. A quick Google turns up that a paper using the device to sequence a human genome has only just been published [0] hence the update to the website. I'm not at all familiar with the technology, but doesn't the fact that experts have only just now been able to sequence human DNA mean it would be pretty unlikely the device could be used as-is for "production" usage?
Re: Nanopore MinION – $1k solid-state DNA sequencers
#10How much are the flow cells?
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