161–170 of 406 posts
Small study, probably not preregistered (didn't find anything about it in the description). Likely Publication Bias or p-hacking. I'm starting to get interested when it's been independently replicated.
At least a practice to include that in the abstract
Earlier quoted context omitted.
Black pepper increases bioavailability of everything by inhibiting your cytochrome p450 enzymes, which increases your vulnerability to toxins.
There’s a difference between bioavailability and half life. Metabolic enzyme inhibition increases half life due to decreased hepatic metabolism of certain drugs. Bioavailability is how much of a drug your body absorbs from the initial dose. Also, black pepper inhibits CYP3A4, not 450.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2574793/
And p450 exists in the brain, which may relate to the OP suggestion that turmeric boosts memory, but doesn't give me confidence that it boosts it in a way that is absent of tradeoffs.
Anti-inflammatories are in the news lots now. Low-dose aspirin, intermittent fasting, turmeric. Why are we chronically inflamed?
Low-dose aspirin is not recommended for people without (potential) heart disease issues as it can be otherwise harmful. And this turmeric study was done on older people as well. So again not really saying much about the wider population.
Earlier quoted context omitted.
Curry is delicious, but it'd get pretty boring to eat it EVERY day.
I wasn't achieving my weight goals like I hoped so I threw my arms up and said "FUCK IT chicken and sweet potatoes for lunch from now on." I've been eating curry-powdered baked chicken for maybe 3 months straight for lunch nearly every day and somehow it's fine. Mostly I'm craving the massive amount of protein it gives me so maybe my body is overriding any "boredom" of the food?
Not really that hard. Tastes great and honestly if you mind too much how the food taste your goals are somewhere else and/or have depleted your mouse buds. Even steel cut outs taste great with only little added salt.
Earlier quoted context omitted.
I am a neurologist. this is actually the exact opposite of what you should care about, which is "does it work to treat ___" In this trial, and 99% of other trials, there is no mechanism provided by the study, only a measurement of causality (which is the same thing as effectiveness). The authors may think they know based on other, prior, basic science research (as they are postulating here), but it does not affect th…
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC300808/
Indians will die of heart attacks and cancer before they become old enough to get alzheimers or other mental issues. Before you downvote me to oblivion, many indian and non-indian dr.s friends have told me this.
>Because curcumin's anti-inflammatory properties may protect the brain from neurodegeneration My very first question was: Please provide a possible physiological pathway for this. I'm so glad it was answered in the very first sentence. So many of these "Superfood does X" studies are just trials with 10 people over a month, with no explanation as to __how__ it could possibly happen. It significantly increases the skep…
I am a neurologist. this is actually the exact opposite of what you should care about, which is "does it work to treat ___" In this trial, and 99% of other trials, there is no mechanism provided by the study, only a measurement of causality (which is the same thing as effectiveness). The authors may think they know based on other, prior, basic science research (as they are postulating here), but it does not affect th…