To me python and perl and two extremes. Perl is almost comical with its use of special characters (which they've embraced even more in Perl 6 with the optional use of unicode symbols in built-in operators) but python went too far the other way IMO. "It looks like pseudocode" sounds nice in theory but people don't typically write huge projects in pseudocode. I don't really like the significant indentation but my main problem is with the awkward scoping rules. I also find that it makes it harder to refactor code (if I copy/paste a snippet at a different level of indentation I can't blindly trust the editor to re-indent it properly).
That being said I agree that these days the tendency across all languages is to go towards fewer special characters, not more. In this context Perl 6's syntax feels a bit anachronistic.
Maybe you'll be able to win a few new user by telling them that in Perl 6 they can use × for *, Ⅻ for 12 and [unicode atom symbol]++ (ironically HN automatically removes the actual symbol when I submit) for atomic incrementation but I expect that many more will recoil in horror. I won't even talk about »=» and the ascii equivalent >>[=]>>.