51–60 of 71 posts
Usually MDMA has the backlash of lowering the amount of serotonin release in your brain the days after you take it, which makes you feel down. The so-called tuesday blues. So how come these people in these treatments aren't getting more depressed after their few hours of excitement?
A huge thank you to Pine for supporting healing-driven science and noticing that MAPS is doing this particularly difficult work with efficiency and integrity.
If MDMA were to become approved medicine in the US, I see it as an important milestone when it comes to getting rid of misguided classifications of drugs as having no medical value even though there are both research and anecdotal evidence suggesting otherwise. I am certain that a change in the US will have impacts on other countries as well. I donated last summer because I sincerely believe this research will have a…
Thanks for your donation! (that will be matched :) The Phase 2 trials and FDA's breakthrough therapy designation along shows strong medical value of MDMA, especially in a clinical context with psychotherapy sessions and a trained therapist. I hope this starts a renaissance in the use of psychedelics to treat, long term (with short term drug applications), many mental conditions.
Earlier quoted context omitted.
Saving lives, changing lives, moving science forward - all better than 6-10% returns. Kind of the whole point of charities is that the work they do is a better return than the market. Otherwise, every charity would be an endowment and they would just consume the 6-10% annual returns for their work.
A lot of charities do like 5% nonprofit stuff and 95% for profit Despite ideals it makes your rebuttal moot
Which charities do this, and why should we believe they're the most effective?
Usually MDMA has the backlash of lowering the amount of serotonin release in your brain the days after you take it, which makes you feel down. The so-called tuesday blues. So how come these people in these treatments aren't getting more depressed after their few hours of excitement?
Usually MDMA has absolutely no observable backlash (it may still harm your brain though, even if you don't feel it, I don't know if it will or not) if you don't take it more often than once in 3 months (or 1 month if you insist, but absolutely never more often), avoid taking too much of it, take enough piracetam, magnesium and antioxidants (acetyl-l-carnitine, acetyl-l-cysteine, vitamins E and C, lipoic acid, CoQ10, green tea extract, grape seed extract etc) before, during and after the MDMA trip, take L-tryptophan+piracetam after the trip, smoke some weed (but don't do it in advance - this can cause a panic attack and nausea), drink enough water, sleep well and take L-tryptophan+piracetam again when you get up. What will follow is usually going to be a rather pleasant state called "afterglow". Taking emoxypine, piracetam, magnesium and St. John's wort during the days after to actually restore the receptors can also be a good idea. I have also heard eating some psilocybin shrooms can prevent MDMA hangover too but I doubt combining psychedelics is a good idea for everybody.
DISCLAIMER: The above is a piece of theoretical knowledge provided for harm-reduction purposes only and not even proven scientifically (I'd be glad if the researchers could consider checking it). Use it at your own risk. Don't take what is not legal in your country. I don't recommend taking MDMA without a prescription though I do recommend to consider harm-reduction measures if you decide to take it. Anyway, make sure you are not allergic to any of the substances you are going to take, are not taking any drugs that may interact with them and don't have any other contraindications.
Earlier quoted context omitted.
A lot of charities do like 5% nonprofit stuff and 95% for profit Despite ideals it makes your rebuttal moot
If all charities do that, his point is moot. Or if the most effective charities do that, his point is moot. Which charities do this, and why should we believe they're the most effective?
Whoever gave you that idea?
That practice has nothing to do with how the world is changed.
I believe most charities practice this, I saw a presentation on it with a bunch of accredited investors, don't have the source.
You can't will your alternate reality into existence.
One big issue not addressed in this post, how is MAPS differentiating between PTSD and BLAST[1] in this CT? They have identical symptoms, but one is psychological and one is physical. Being unable to differentiate them could cause some SERIOUS error in the results. Have you thought about how you are going to address that? [1]BLAST is a traumatic brain injury similar to CTE. It is caused by shockwaves emanating from e…
One big issue not addressed in this post, how is MAPS differentiating between PTSD and BLAST[1] in this CT? They have identical symptoms, but one is psychological and one is physical. Being unable to differentiate them could cause some SERIOUS error in the results. Have you thought about how you are going to address that? [1]BLAST is a traumatic brain injury similar to CTE. It is caused by shockwaves emanating from e…
One could select for people who were not subject to an actual explosion?
This seems like evidence towards Gwern's theory that pineapple fund is a retired dark net drug dealer...