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Pineapple Fund Offers $4M Matching Grant to MAPS for MDMA Research

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31–40 of 71 posts

Re: Pineapple Fund Offers $4M Matching Grant to MAPS for MDMA Research

#31
i for one welcome our new crypto-currency funded drug research clinical trials. Please try to be as ethical and scrupulous when doing your research as possible: it's important that we have high quality scientific results, regardless of whether they support our hypotheses, so that people trust the outcomes.

Re: Pineapple Fund Offers $4M Matching Grant to MAPS for MDMA Research

#32

If MDMA were to become approved medicine in the US, I see it as an important milestone when it comes to getting rid of misguided classifications of drugs as having no medical value even though there are both research and anecdotal evidence suggesting otherwise. I am certain that a change in the US will have impacts on other countries as well. I donated last summer because I sincerely believe this research will have a…

Thanks for your donation! (that will be matched :) The Phase 2 trials and FDA's breakthrough therapy designation along shows strong medical value of MDMA, especially in a clinical context with psychotherapy sessions and a trained therapist. I hope this starts a renaissance in the use of psychedelics to treat, long term (with short term drug applications), many mental conditions.

Any chance I can get you on my show, anonymously? I have so many questions. This is Chris DeRose.

Re: Pineapple Fund Offers $4M Matching Grant to MAPS for MDMA Research

#34
post #20

Earlier quoted context omitted.

It honestly feels like this is what has happened. I have to talk on the phone all day at my job and was not suited to it at all, and I won't pretend I suddenly enjoy it, but now I find it way easier to get thru than I did before. I'll probably do it again. I just wish there were more studies so I could know how often is safe and optimal to take it.

On the very safe side: Not more often than every 6 weeks. Ideally not more than 15 doses in lifetime (that's what MAPS guidelines say). Stop once you are sad beyond the 'blue Tuesday' (not everyone has a blue Tuesday, but after repeated use it usually starts to happen and gets worse). There is quite some literature, sadly not nicely structured and concentrated in one place as far as I know.

I belive what you're saying isn't true and neither can I find a direct link to a MAPS guideline saying anything about the 15 doses in a lifetime.

In my experience I had blue mondays way worse on my first 3 times, and then I've got to the point where I am no longer blue on the days after. That would be my 6 times over a 5 year period.

Re: Pineapple Fund Offers $4M Matching Grant to MAPS for MDMA Research

#37
post #30

This is fantastic. I recently helped a few of the NGOs selected by Pineapple get their tech together to accept the funds. It gave me a chance to learn more (as much is public) about the fund and love hearing about bolder moves like this to make such an impact. Being close to the NGOs that did receive the funds, I can say first hand just how much of a difference this macro-funding is making for real orgs that care so…

Thanks Jim! Let me know if there's anything I can do to make things easier for the NGOs!

Some days, I still wake up and I'm a little bit astonished about the impact that my bitcoins can have. I certainly would've never predicted this when I first got into bitcoin.

Re: Pineapple Fund Offers $4M Matching Grant to MAPS for MDMA Research

#38
post #6

Earlier quoted context omitted.

I can anecdotally confirm this. I took MDMA under pretty normal party circumstances and honestly it was life changing. I've found it easier to be friendly, talkative, relaxed, and positive, even weeks later. I'm interested to see how long these effects last. My intrusive thoughts have been lowered and my overall outlook is more positive. I don't have PTSD, but I do have depression, anxiety, and unofficially, I probab…

Have plenty of friends that have overcome social anxiety they've had their entire lives with just one night of MDMA.

I just also want to note that there are also people who have experienced negative reactions with just one night of MDMA. All drugs have side effects.

While I think MDMA-assisted psychotherapy is extremely promising, MDMA itself is definitely not risk free (especially when obtained from unregulated and adulterated sources); and various complications can and do occur.

Re: Pineapple Fund Offers $4M Matching Grant to MAPS for MDMA Research

#40
One big issue not addressed in this post, how is MAPS differentiating between PTSD and BLAST[1] in this CT? They have identical symptoms, but one is psychological and one is physical. Being unable to differentiate them could cause some SERIOUS error in the results. Have you thought about how you are going to address that?

[1]BLAST is a traumatic brain injury similar to CTE. It is caused by shockwaves emanating from explosives. Symptoms are near identical to PTSD.

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