61–70 of 104 posts
Nothing like a good mental colonic with a brutal dissolution of ego to increase that amygdala response, right?
I can vouch for the antidepressant properties of psilocybin, as well as it's nearly miraculous efficacy at stopping cluster headaches. If any of you are unaware of cluster headaches, they are also called suicide headaches, because the pain is so great that many people just kill themselves. The pain level has few peers, it's been compared to amputation without anaesthetic. For me, the bulk of the sensation is of one o…
I can vouch for the antidepressant properties of psilocybin, as well as it's nearly miraculous efficacy at stopping cluster headaches. If any of you are unaware of cluster headaches, they are also called suicide headaches, because the pain is so great that many people just kill themselves. The pain level has few peers, it's been compared to amputation without anaesthetic. For me, the bulk of the sensation is of one o…
I was not depressed at the time - I might have been a little down - but my mood was better - things that used to annoy me now annoyed me much less, while things that used to make me happy made me even happier.
Since LSD and Psilocybin are so similar in their effects, I would not be surprised if the mechanism turns out to be the same.
Now that I think if of it, I remember a mushroom experience when I was maybe 19 or 20 years old, and, at the time, quite unhappy about my life, quite likely even depressed. I did mushrooms with a friend whose parents were on vacation. The trip itself was very depressing. But when I woke up the next morning, I was happier than I had been in months, and that, too, lasted several weeks.
I can vouch for the antidepressant properties of psilocybin, as well as it's nearly miraculous efficacy at stopping cluster headaches. If any of you are unaware of cluster headaches, they are also called suicide headaches, because the pain is so great that many people just kill themselves. The pain level has few peers, it's been compared to amputation without anaesthetic. For me, the bulk of the sensation is of one o…
I can vouch for the antidepressant properties of psilocybin, as well as it's nearly miraculous efficacy at stopping cluster headaches. If any of you are unaware of cluster headaches, they are also called suicide headaches, because the pain is so great that many people just kill themselves. The pain level has few peers, it's been compared to amputation without anaesthetic. For me, the bulk of the sensation is of one o…
Relevant talk from Horizons:
Nothing like a good mental colonic with a brutal dissolution of ego to increase that amygdala response, right?
This is a reddit quality comment. On what basis do you justify classifying the treatment as brutal? Or that the dose was high enough that the test subjects underwent ego death? Were you just exaggerating for comic effect and didn't really have anything to add?
Earlier quoted context omitted.
To some degree, it absolutely is. At the very least, your reality needs to shift. That's the whole idea of healing depression... there are things in your reality that need shifting. I'm also sure that psilocybin isn't the only molecule involved. And I'm also sure that if someone isn't ready to take active ownership of their mental health into taking psilocybin could be just as moot as any other substance. Healing is…
> To some degree, it absolutely is. At the very least, your reality needs to shift. That's the whole idea of healing depression Hold on now, you're deciding what the mechanism of action is without merit. Consider some of the studies being done for depression with Ketamine. In those studies, they're finding that the psychoactive component isn't the one causing the improvement- just a byproduct of it created during met…
And there are more and more studies about the mechanism of psychedelics such ad psilocybin and LSD coming out, essentially telling the same story.
Joins other studies from NYU investigating psilocybin mitigation of anxiety in advanced stage cancer patients. As well as a comprehensive survey by psychiatrists at Johns Hopkins showing 84% of those who tripped describing the experience as somewhat beneficial: Survey study of challenging experiences after ingesting psilocybin mushrooms http://journals.sagepub.com/doi/full/10.1177/026988111666263... As federal dollar…
Are there any studies on psilocybin mushrooms on schizophrenia-spectrum people?
This is all the more important that there are few medical options for depression: SSRIs are the commonly used ones.
SSRIs are used to treat a different class of depression.
Anecdotally, one-time use of LSD(which acts similarly to psilocybin, primarily through 5-ht2a agonism) set me on a path to self improvement. I had depression for years during my puberty, teens, and early adulthood. I contemplated suicide regularly and had a pessimistic outlook on life. I dropped out of college in my first semester despite taking and passing multiple AP classes in high school because I didn't see the…
Also anecdotally, I took a fairly large amount of magic mushrooms once, and it was an awful episode that left me with anxiety attacks for many months afterwards. I saw no life improvement from this experience, and regret having ever dabbled recreationally.