My impression is that it is not only about topics, but also perceived intentions (and if you step, however unintentionally, on a trigger (of a landmine)). I wrote Dating for Nerds: Gender differences ( http://p.migdal.pl/2017/09/30/dating-for-nerds-gender-differ... ) and got no backlash (much to my surprise, though). From my experience nerds (and aspies in particular) talk mostly to exchange information (learn, share…
The problem is that there's a very slippery slope between stating a difference, ascribing causality (the difference is due to biology, for instance), and justifying it as a moral imperative (we should treat men and women differently).
It's dangerous because if differences between groups are easy to pinpoint, they're much harder to explain. Even if you can get to a plausible causal mechanism, it doesn't say anything about how things should be anyway.