321–330 of 459 posts
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Are you taking it with food? I think it dissolves in fat, so you might want to take it with some oil for better absorption.
Yup - it's a fat soluble vitamin - this is a very good point to bring up. I made the "taking it with my low fat meal of the day" (breakfast) and made a change to correct that.
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Good question! The scientific method does not include references to "impact factor" :)
I mean, it does. The "fairy tale" that one hears in high school doesn't, but we put aside fairy tales when we became adults. If you are done with the "undergrad level" of Popper and Kuhn it is worth reading Imre Lakatos's work on philosophy of science. It contains a moment where one realizes that research programs live or die by this "impact factor" and that this living or dying is a key part of the overall methodolo…
1. Imre Lakatos and maturity are great, both implying that you should not apply the aforementioned rule of thumb to an individual paper - an individual in the population - whether it was published in Nature or an insignificant contender.
2. Your memetic approach is also good, but incomplete: the objective function in case of these journals is maximizing the impact factor - so we can conclude that "PrevMed is less successful in maximizing the impact factor than some competitors, or it is a younger journal, or ..." Yes, imact factor and quality correlate in the long run, but we are not at undergrad level.
3. "A low impact-factor ... directly says" - Not directly. Also, most of the journals - not to mention conferences - do not even have an impact factor.
4. "...this journal sucks" - Most of the people writing in these kind of journals have given up a lot to contribute something modest. The editor of this journal is probably emailing with reviewers at 1am or so. Just saying...
Anecdotally, I had this discussion with a cardiovascular interventionist specialist about seven or eight years ago when I was managing a team of cardio theatre orderlies in a private hospital. He made the comment, "mark my words, in about five to ten years time there will be a major scare about needing to absorb more vitamin D". His opinion was that the increase in sunscreen usage and the push to avoid skin cancer by…
This article seems to be a low quality review of other research with a clickbatey title (full text here: https://www.jpmph.org/journal/view.php?doi=10.3961/jpmph.16.... ). Pubmed is sort of like arxiv.org and the fact this has an nih.gov base url should not be taken as an endorsement of it by the NIH. That said I do actually believe that more then the recommended amount of vitamin D can be beneficial and the recommen…
As for food products, there aren't that many natural sources of vitamin D. Milk is fortified with vitamin D but doesn't come with it naturally.
Given how few sources of vitamin D there are: http://www.whfoods.com/genpage.php?tname=nutrient&dbid=110 I don't see how our species could have evolved to depend on vitamin D (other than being outdoors).
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That's me. Any idea how well supplements are absorbed? Which are better or worse?
Get a blood test first so you know your Vitamin D level (they're cheap: https://news.ycombinator.com/item?id=15869485 ), maybe you already get enough from your diet. If you do need supplementation, then Vitamin D3 (specifically Cholecalciferol) is vastly better absorbed than Vitamin D2. If you want a specific recommendation, buy this: https://www.amazon.com/gp/product/B07234TTCC and take it twice per week (Sunday & T…
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Vitamin K can be dangerous for a not insignificant part of the population, many of whom don't realize they might be sensitive to it. It is a very strong addition to the body and affects blood clotting and interactions with many medications. If you want to safely increase vitamin K, just eat more dark green vegetables like spinach. There's no need to overdo it with K or it could be a regrettable error.
The best „normal“ dietary source is Gouda cheese, and almost an order of magnitude better, Natto (though that’s hard on the taste buds).
Natto is not "normal". It is an acquired taste. The acquisition of said taste is a difficult, nauseating, and extremely stinky path. Besides that, most of the vitamin K from natto is as MK-7.
Animal-sourced vitamin K is mostly menatetrenone (aka menaquinone MK-4) whereas vitamin K from fermentation bacteria is various lengths of menaquinone, of which only MK-4 and MK-7 have good vitamin K activity in humans, and the MK-4 form is usually nearly absent. Plant-sourced K is as phylloquinone, which has to be converted to menatetrenone in the body.
So also-good sources are egg yolks from free-ranging, pastured laying hens and butter from free-ranging, pastured dairy cows. Basically, you need to eat parts of animals that were raised by traditional, non-battery farming, particularly the livers and adipose tissue. Poultry animals such as geese, chickens, and ducks are good for this. Apparently, the oil from rendered emu fat is also high in vitamin K.
Cheeses have some MK-4 from the milk and some MK-7 from the bacteria, but a lot of their K is in less easily assimilated forms. That's probably good enough unless you have some rare and nigh-undetectable enzymatic deficiency that interferes with conversion of MK-9 to MK-4, or something.
I suppose that if you force-fed some geese a bunch of natto, and then mashed up their livers into a paste, that would be a great vitamin K pate. I think I'd rather just swallow a pill.
I have been taking 5000IU Vitamin D for the past 7 years, with a little more over the winter months. It's stupidly cheap, I get 360 5000IU capsules for $13, so it has cost me less than $100 over that period. Anecdotally, it was a game changer for me personally. I got less sick during the winter, and my overall wellbeing improved greatly. A word of advice, increase Vitamin K intake aswell. Vitamin D helps calcium abso…
Just a counter-point. Vitamin D didn't help me with SAD. SAD seems only addressed for me by a proper full spectrum lamp for 30 minutes a day in the winter.
Anecdotally, I had this discussion with a cardiovascular interventionist specialist about seven or eight years ago when I was managing a team of cardio theatre orderlies in a private hospital. He made the comment, "mark my words, in about five to ten years time there will be a major scare about needing to absorb more vitamin D". His opinion was that the increase in sunscreen usage and the push to avoid skin cancer by…
The NIH guys also did a study that said that even in tropical countries, Vitamin D absorption has fallen dramatically because of lifestyle changes. One of the probable factors is the lust for fair skin. I routinely see people covered from head to toe to help them stay fair skinned, even kids are sent to play covered in full sleeve clothing. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897581/