Live data from Hacker News

Ketamine lifts rodents' mood only if administered by male researchers

nature.com

161–170 of 258 posts

Re: Ketamine lifts rodents' mood only if administered by male researchers

#161
post #57

Earlier quoted context omitted.

Inadequate controls = attempting to measure fine effects (gender normalized animal behavior) using crude methods (rat study).

Accuracy or precision. Pick one?

Well, why should anybody not pick accuracy every time?

Re: Ketamine lifts rodents' mood only if administered by male researchers

#162
post #22

Earlier quoted context omitted.

Were rats as sensitive as mice?

Fwiw I have been assured that Big Pharma will swap out a set of mice (or whatever the test species is) as a way to find the results they're looking for. This was told to me by someone who does research for Big Pharma. Someone who I have no reason not to trust.

But how can we trust you to tell the truth about this?

Re: Ketamine lifts rodents' mood only if administered by male researchers

#163
post #18

It's interesting to think about what this could mean for people. We use these mice because they often are convenient models for humans. Are our moods are just as affected by combinations of lots of little things like these - smells, hormones, chemicals in the cleaners, hair products etc. On the scary side imagine being able to use this for evil. Spray something like this on your product to manipulate people's hormona…

> Are our moods are just as affected by combinations of lots of little things like these - smells, hormones, chemicals in the cleaners, hair products etc.

Is that a question? Isn't this well known?

Re: Ketamine lifts rodents' mood only if administered by male researchers

#164

Earlier quoted context omitted.

Accuracy or precision. Pick one?

Well, why should anybody not pick accuracy every time?

Because, in the extreme, accuracy without precision doesn't tell you a damn thing.

Re: Ketamine lifts rodents' mood only if administered by male researchers

#165
post #59

Earlier quoted context omitted.

You said "haven't been there for years" which means you came from 4chan. So does your behavior, pretending you don't know the word "trap" or purposefully mis-gendering is an insult to transgender people. That bullshit doesn't play here. You still haven't asked any questions worth answering. https://www.glaad.org/reference/transgender >Defamatory Language >Defamatory: "deceptive," "fooling," "pretending," "posing," "t…

>pretending you don't know the word "trap" I'm not pretending to not know the word; it made sense on sight to me as "someone who fools you". Easiest term around. And that is clearly a concept of its own not a synonym for transsexuals , hence my confusion when a poster gets flagged for an affront to them. You have actually been helpful now though, despite thinking you're slamdunking me. Passing is a bad word now too?…

Next you're going explain to me that you're not a "homophobe" because you're not literally "afraid" of homosexuals, you just hate them without fearing them. That's not the way language works, and I've heard all of your arguments before. You have nothing to contribute to the conversation.

Re: Ketamine lifts rodents' mood only if administered by male researchers

#167

Earlier quoted context omitted.

Well, why should anybody not pick accuracy every time?

Because, in the extreme, accuracy without precision doesn't tell you a damn thing.

Just like precision without accuracy, but if you get accuracy you know you have a problem, but with only precision you are hopelessly misled.

If it was a strict trade-off, I would agree that the answer was somewhere on the middle. But it isn't. Most of the things that give you precision will also give you accuracy. The few things that let you exchange one for the other look too much like cheating, and seem to always have much greater impacts on accuracy than on precision.

Re: Ketamine lifts rodents' mood only if administered by male researchers

#168

Earlier quoted context omitted.

In college we used to joke that animal behavior should be called animal misbehavior. We literally had one member of our lab group that could work with the mice and get sensible results. Neither of the guys could get any data that made sense, one of the women owned a cat and none of the results she had made any sense, and the fourth person (a woman) had no problem. I'm not sure if anybody suspected that rats reacted d…

I wonder how practical it would be to automate all the rodent handling/experimenting? Because that seems like it'd be the only way to properly remove such unaccountable influences, like people smelling of cat/giving off different smells and thus influencing the reactions of the animals. Couldn't it also be possible that rodents reacting like that is the result of established practices? I.e.: Rodents get only handled…

Even automation would not solve this issue. If these results are scent related, then it is quite possible that different automation methods would produce different scents, or even the same method, in a different environment / location.

This is a fascinating issue.

Re: Ketamine lifts rodents' mood only if administered by male researchers

#169

Earlier quoted context omitted.

> the actors behind the cartoon are reading a script written by someone... So.. it really doesn't matter who teaches and who listens, because ultimately they're both actors reading from a script. How does that play in favor of your argument? Not to mention the woman he's explaining to is a scientist researcher, and at the end of the video, they have Dr. Azra Raza as a guest (who is also a woman) to further solidify t…

the cartoon depicts an incompetent woman scientist being talked-down to by an arrogant dick! It has the form: woman: " science says X" man : " actually the truth is Y" The jerk also talks-down to us the audience. It's terrible science-education and it's not "humor"

Would it be any better if the genders of the actors were reversed?

"mansplain" is a gender-biased criticism of behavior. It implies that the gender of the participants is the problem, rather than the attitudes or behavior.

But apparently the mice in the study react to the gender, so maybe it's germane...

Re: Ketamine lifts rodents' mood only if administered by male researchers

#170

Earlier quoted context omitted.

You're an ass. Comments like this make me hate people. Why does it even matter what their sexuality is? And why does that group of people need a special name

It's not his first transphobic remark. Not only does he call trans people "traps", but he also objects to using proper pronouns because "I don't like my speech being dictated". It's easy to guess what he's obsessed with and ashamed about, and it's not about his lack of ability to treat people with respect. https://news.ycombinator.com/item?id=15242499 And FYI, in case you're a nice enough person to have missed the re…

Are you actually implying that my making a joke is evidence of some deep dark secret about my sexuality?
Post reply on HN