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Choosy Eggs May Pick Sperm for Their Genes, Defying Mendel’s Law

quantamagazine.org

31–40 of 62 posts

Re: Choosy Eggs May Pick Sperm for Their Genes, Defying Mendel’s Law

#31

Earlier quoted context omitted.

Just met an airbnb host with the exact same story. Tried for years then broke up - both had kids right away with their new partners

And a miscarriage is the egg doing a "Oops. Got that one wrong"?

You cannot throw this kind of jokes around given how this subject can be hard to read for people to which it happened. HN is a community with people of lot of different backgrounds so it's important to be careful.

Re: Choosy Eggs May Pick Sperm for Their Genes, Defying Mendel’s Law

#32
post #31

Earlier quoted context omitted.

And a miscarriage is the egg doing a "Oops. Got that one wrong"?

You cannot throw this kind of jokes around given how this subject can be hard to read for people to which it happened. HN is a community with people of lot of different backgrounds so it's important to be careful.

Please don't speak for other people we don't need your protection.

Edit: miscarriages are incredibly common. This will/has affected people of almost all backgrounds. The culture of silence on the topic leaves you totally unprepared for it as a reality.

Re: Choosy Eggs May Pick Sperm for Their Genes, Defying Mendel’s Law

#33

Earlier quoted context omitted.

Just met an airbnb host with the exact same story. Tried for years then broke up - both had kids right away with their new partners

And a miscarriage is the egg doing a "Oops. Got that one wrong"?

We had this in biology in high school, don't remember the exact details but essentially some gene combinations just "don't work", and in mammals that manifests as a miscarriage.

Re: Choosy Eggs May Pick Sperm for Their Genes, Defying Mendel’s Law

#34

Does this (read: could this) help explain why some couples have problems conceiving? Perhaps, at least in some cases, the egg is saying, "no way buddy."

Unlikely. As a selective mechanism its effect would be very subtle, and there are other, well-known, much stronger mechanisms that prevent conception. Age of the mother was mentioned. More generally, it’s defects in the oocyte’s ability to perform chromosome segregation or to nest in the uterine lining.

Re: Choosy Eggs May Pick Sperm for Their Genes, Defying Mendel’s Law

#36

Earlier quoted context omitted.

> Perhaps, at least in some cases, the egg is saying, "no way buddy." Assuming this is true, it would be happening in less than 1% of cases (given the prevalence of male-factor infertility and the prevalence of its known causes). So if such an ability exists, it doesn't seem to be getting used very often. Which, given the evolutionary complexity that would be required to evolve such a system, seems surprising. So my…

I thought that partner incompatibility was extremely common?

Just incompatibility, without the partner. Fluids pH problems are much more common than you'd think, and it has nothing to do with the partner (besides being treatable). And it's just one of the many problems that may occur, but none of them is like a partner issue because your bodies don't "match".

Re: Choosy Eggs May Pick Sperm for Their Genes, Defying Mendel’s Law

#38

This probably answers a question I have about genetics - that there just isn't enough variety if reproduction was random. Genetic differences that have no bearing on survivability, like skin patterns or colors or whatever, should be widespread through every species, but they're not.

That's really interesting to think about. Somewhat related, I asked a geneticist once why there was so much diversity in humans vs pigeons which all looked the same to me.

He said, "We're tuned to notice differences between people, not pigeons. Perhaps we all look the same to them!"

Perhaps there is precisely this sort of random variation in the differences we don't notice, because by being oblivious to them they are not sexually selected for or against?

Re: Choosy Eggs May Pick Sperm for Their Genes, Defying Mendel’s Law

#39
post #31

Earlier quoted context omitted.

And a miscarriage is the egg doing a "Oops. Got that one wrong"?

You cannot throw this kind of jokes around given how this subject can be hard to read for people to which it happened. HN is a community with people of lot of different backgrounds so it's important to be careful.

I don't think there was any joke intended. Often times someone will try to understand a murky topic by creating a (often personified) metaphor.

Re: Choosy Eggs May Pick Sperm for Their Genes, Defying Mendel’s Law

#40
post #31

Earlier quoted context omitted.

You cannot throw this kind of jokes around given how this subject can be hard to read for people to which it happened. HN is a community with people of lot of different backgrounds so it's important to be careful.

Please don't speak for other people we don't need your protection. Edit: miscarriages are incredibly common. This will/has affected people of almost all backgrounds. The culture of silence on the topic leaves you totally unprepared for it as a reality.

The problem is that 'miscarriage' covers everything from what seems like just a late period to something really quite awful.

I agree that silence doesn't help and on HN is most likely unnecessary. But in general conversation it is reasonable to be a bit more circumspect.

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