Why I’m Digging Deep Into Alzheimer’s

Post by goialoq » Mon, Nov 13, 2017, 10:00 PM UTC

beamer1979 wrote: post #102

koolba wrote: post #53

Earlier quoted context omitted.

> ... so long as we stay away from say live telemetry to insurers ... Consumers have demonstrated that they're willing to save $5-20 a month in exchange for sending gym checkins[1], daily steps counts, or digital monitoring of their driving habits[2] uploaded to their insurers. I don't think it'll ever be mandatory but I can see a day where the "discount" for agreeing to continuous monitoring and data upload is so gr…

"I don't think it'll ever be mandatory but I can see a day where the "discount" for agreeing to continuous monitoring and data upload is so great that it'd be cost prohibitive for the average consumer to not be a part of it." I would be looking to my government to ensure such unwanted and unwelcomed intrusions into an individual's private life by private companies aren't required to achieve that. Whether that be thro…

Post by allenz » Mon, Nov 13, 2017, 11:20 PM UTC

Nomentatus wrote: post #124

stdgy wrote: post #121

Earlier quoted context omitted.

Bill addresses this in the piece: I’m making this investment on my own, not through the foundation. The first Alzheimer’s treatments might not come to fruition for another decade or more, and they will be very expensive at first. Once that day comes, our foundation might look at how we can expand access in poor countries. It's intriguing they're able to draw that line, but it makes sense if they want to keep the Gate…

But note that obesity and diabetes (Alzheimer's is sometimes called diabetes 3 and called part of the metabolic syndrome) are now hitting the third world HARD. Something that was highly predictable, and which I feared and mentioned at the time.

Post by ZenoArrow » Mon, Nov 13, 2017, 11:55 PM UTC

Filligree wrote: post #15

ggambetta wrote: post #6

Cynical answer: "because I'm getting old" :) Whatever the reason, this has the potential of being life-changing for a lot of people. Would love to see more billionaires involved with this kind of initiative.

The reason doesn't really matter, this is still incredibly valuable work. Death is terrible, and should be eradicated, but Alzheimer's is a few steps above that. There's nothing worse than seeing a loved one be slowly destroyed by that horrific disease, and I'm so glad there are people willing to work on it.

Post by digikata » Tue, Nov 14, 2017, 12:10 AM UTC

louprado wrote: post #76

The documentary "Under our Skin" details Alan MacDonald's breakthrough research on how Lyme disease causes Alzheimers. The 4 minute trailer is worth a watch[1], but basically Lyme disease is found in 7 or 10 brains of Alzheimers patients (small sample set). The Lyme disease spirochete literally drills countless pathways in the brain and that causes slow dementia. That spirochete also creates a biofilm which makes it…

Post by busterarm » Tue, Nov 14, 2017, 1:29 AM UTC

vimy wrote: post #123

jdpigeon wrote: post #91

Earlier quoted context omitted.

Former Alzheimer's researcher here. I've never heard of this before. Some cursory googling only turns up a sole author publication by Alan MacDonald in Medical Hypotheses and a few news pieces by dodgy organizations like the Spirochaetal Alzheimer's Assocation. Despite what a lot of people learn in undergrad psych classes, the evidence linking amyloid beta and tau to AD is quite good and getting stronger with every n…

Maybe there is no correlation because Lyme disease is severely underreported. A couple years ago, the CDC stated that official numbers were likely underreported by a factor of 10. From 30,000 yearly cases to 300,000 https://www.cdc.gov/media/releases/2013/p0819-lyme-disease.h... There was also the case of actor/songwriter Kris Kristofferson being misdiagnosed with Alzheimer's for years. He had Lyme. This is anecdotal…